Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
Prevalence of APC and PTEN Alterations in Urachal Cancer
Pathol Oncol Res. 2020 Oct;26(4):2773-2781. doi: 10.1007/s12253-020-00872-6. Epub 2020 Aug 4.ABSTRACTUrachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC). Adenomatous polyposis coli (APC) is the most frequently affected gene in CRC, but the prevalence and significance of its alterations in UrC is poorly understood. In addition, loss of phosphatase and tensin homologue (PTEN) was shown to be associated with therapy resistance in CRC. Our primary aim was to assess specific genetic alterations including APC and PTEN in a large series of UrC samples in order...
Source: Pathology Oncology Research - August 6, 2020 Category: Pathology Authors: Nikolett Nagy Henning Reis Boris Hadaschik Christian Niedworok Orsolya M ódos Attila Szendr ői Krisztina B író Thomas Hager Thomas Herold Jason Ablat Peter C Black Krzysztof Okon Yuri Tolkach Anita Csizmarik Csilla Ol áh David Keresztes Felix Bremmer Source Type: research
