Mini Bioethics Academy at University of Minnesota ’s Center for Bioethics
Join me for the Mini Bioethics Academy at the University of Minnesota’s Center for Bioethics. (Source: blog.bioethics.net)
Source: blog.bioethics.net - April 15, 2019 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

Who Decides? Perspectives from Key Stakeholders in Adolescent Advance Care Planning
On April 19, 2019, Jennifer Needle, MD, MPH (Assistant Professor, Center for Bioethics, University of Minnesota) will give an Ethics Grand Rounds talk on "Who Decides? Perspectives from Key Stakeholders in Adolescent Advance Care Planning." Advance ca... (Source: blog.bioethics.net)
Source: blog.bioethics.net - March 28, 2019 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

2019 Health Law Professors Conference
Conclusion (Source: blog.bioethics.net)
Source: blog.bioethics.net - March 27, 2019 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

Decision-Making in the ICU - The Problem Is Us
byDrew Rosielle (@drosielle)Annals of Internal Medicine has published a fascinating trial of a web-based surrogate decision-making tool aimed at improving decisions for patients receiving prolonged mechanical ventilation in an ICU.It ' s one of the most fascinating trials I ' ve read in a long time, and also somewhat of a monster (in size/scope of data presented) - there are 4, lengthy online supplements attached to it (!), which is daunting, and so I ' m mostly just going to write here about what I find most interesting about it.Which is that I think this may be the trial which should convince us all that what ' s ' wrong...
Source: Pallimed: A Hospice and Palliative Medicine Blog - March 10, 2019 Category: Palliative Care Tags: advance care planning annals of internal medicine communication hospital icu journal article prognosis rosielle The profession Source Type: blogs

Postdoc: suppressive soil microbiomes, Univ Minnesota
Post-doctoral researcher position:  Two, three-year post-doctoral positions are available in the Kinkel laboratory at the University of Minnesota.  We are seeking post-doctoral scientists to work on two new project studying the factors the mediate the composition and functional capacities of soil microbiomes to support plant productivity.  One project utilizes a unique, long-term, 5-species crop monoculture experiment to test predictions of a mechanistic model for the development of disease-suppressive microbiomes.  The second project explores variation in the coevolutionary dynamics of soil microbiomes in response...
Source: Fungal Genomes and Comparative Genomics - February 19, 2019 Category: Genetics & Stem Cells Authors: Jason Stajich Tags: microbiome postdoc suppressive soils minnesota postdco Source Type: blogs

Goodbye to Compounded Analgesic Creams
This study is one of the largest and best-designed study I ' m aware of of these creams, and the findings are pretty clear: such creams benefit patients via placebo mechanisms, aka they don ' t work.Note that there is a separate body of research on some other topicals which should not be confused with this study. Eg, the 5% lidocaine patch for post-herpetic neuralgia, topical capsaicin for a variety of neuropathies, and at least some topical NSAIDs for osteoarthritis, and topical opioids. I ' m not broadly endorsing those either - it ' s complicated - however they weren ' t tested here and the take home point is we should ...
Source: Pallimed: A Hospice and Palliative Medicine Blog - February 11, 2019 Category: Palliative Care Source Type: blogs

YAMMMM: Yet Another Mostly Male Microbiome Meeting - Gut Microbiota for Health World Summit 2019
Uggh. In the middle of a faculty retreat and saw a Tweetabout this meetingand could not help looking at their speaker list. And am not impressed. Too many male speakers.Gut Microbiota for Health World Summit 2019A Meeting to HearMen (81%) NotWomen (19%) Discussing Microbiota*, **YAMMMM: Yet Another MostlyMale Microbiome MeetingGail A. Hecht, MD, MS, Loyola University Medical Center (U.S.)Jack A. Gilbert, PhD, University of Chicago (U.S.)Session Moderator:Giovanni Barbara, MD, University of Bologna (Italy)Suzanne Devkota, PhD, Cedars-Sinai Medical Center (U.S.)Magnus Simren, MD, PhD, AGAF, University of Gothenburg...
Source: The Tree of Life - November 29, 2018 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs

10th Anniversary of Dr. Smith's ECG Blog: First Post was November 7, 2008
This was the first post 10 years ago today:ST depression: is it ischemia? No, hypokalemia.A bit of history:K. Wang formerly sent out a paper ECG through interoffice mail called " The EKG of the Week. "  When he left Hennepin to go to the University of Minnesota, I decided to start sending out the " EKG of the Week " by email to any residents and faculty in our department who wanted it.  Scott Joing, the founder of our department educational sitewww.hqmeded.com suggested that it would be easier just to blog it and send out the link to the blog. It sounded like a good idea.  He set it up and called i...
Source: Dr. Smith's ECG Blog - November 7, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

Nope. We STILL Shouldn't Claim Prolonged Survival in Hospice and Palliative Care
by Drew Rosielle (@drosielle)A group of investigators from Tulanerecently published a meta-analysis in Annals of Behavioral Medicine indicating that outpatient palliative care improves survival and quality of life in advanced cancer patients (free full-text available here, although I ' m not sure if that ' s permanent).Perhaps you ' ll remember inJune of this year when I pleaded with our community to stop claiming that palliative care prolongs survival (my littleTwitter rant about this starts here).My basic plea was this:Hospice and palliative care community, I ' m calling for a moratorium on all blanket, unqualified claim...
Source: Pallimed: A Hospice and Palliative Medicine Blog - November 2, 2018 Category: Palliative Care Tags: journal article outpatient pallimed writing group research research issues rosielle The profession Source Type: blogs

Antipsychotics Don't Help ICU delirium
by Drew Rosielle (@drosielle)It just gets worse and worse for the idea that antipsychotics have efficacy for delirium.Last year Iposted about the RCT of haloperidol, risperidone, or placebo for delirium symptoms in ' palliative ' patients. I ' m pretty sure I called for more controlled, ' high quality, ' trials, and we are lucky enough to have another.This one is arandomized, double-blinded, registered, controlled trial of haloperidol, ziprasidone, or placebo for ICU delirium, just published in NEJM.The trial took place in a geographically diverse group of US-based intensive care units. They enrolled adult patients in medi...
Source: Pallimed: A Hospice and Palliative Medicine Blog - October 25, 2018 Category: Palliative Care Tags: delirium icu journal article rosielle Source Type: blogs

Screening of Documentary Film THE EXPERIMENTS that Exposed Most Spectacular Human Research Scandals
Come to the University of Minnesota for this film and discussion on October 29, 2018. Bosse Lindquist’s documentary trilogy The Experiments exposed one of the most spectacular human research scandals of the modern era. (Source: blog.bioethics.net)
Source: blog.bioethics.net - October 22, 2018 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

Fight Aging! Newsletter, October 15th 2018
This study suggests that exocrine glands can be induced from pluripotent stem cells for organ replacement regenerative therapy. Replacement of Aged Microglia Partially Reverses Cognitive Decline in Mice https://www.fightaging.org/archives/2018/10/replacement-of-aged-microglia-partially-reverses-cognitive-decline-in-mice/ Researchers here report on a compelling demonstration that shows the degree to which dysfunctional microglia contribute to age-related neurodegeneration. The scientists use a pharmacological approach to greatly deplete the microglial population and then allow it to recover naturally. Th...
Source: Fight Aging! - October 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs