Management of renal angiomyolipomas in TSC
mTOR inhibition is likely to transform management of tuberous sclerosis complex and the results of landmark trials are being studied to see if the encouraging reductions in tumour size translate into improved outcomes for patients in the long term (Source: Pharmacy Europe)
Source: Pharmacy Europe - October 16, 2015 Category: Drugs & Pharmacology Authors: ebercott Tags: Featured Articles Source Type: news
For children with rare genetic disorder, more extensive epilepsy surgery yields better seizure control
Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 15, 2015 Category: Science Source Type: news
[RS Housden] Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi
Combining targeted CRISPR-mediated gene editing with an RNAi-mediated screen identifies candidate drug targets. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 9, 2015 Category: Science Authors: Benjamin E. Housden, Alexander J. Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie E. Mohr, Brendan D. Manning, Norbert Perrimon Source Type: news
Topical timolol reduces facial angiofibromas in tuberous sclerosis
Topical beta-blockers could be an alternative to rapamycin for the treatment of angiofibromas after traditional destructive procedures such as ablative laser resurfacing, according to a case study published in the Aug. 24 edition of Pediatrics.
A 26-year-old woman with tuberous sclerosis complex... (Source: Skin and Allergy News)
Source: Skin and Allergy News - August 24, 2015 Category: Dermatology Source Type: news
Jim Carrey Apologizes For Tweeting Photo Of Boy With Autism In Anti-Vaccine Rant
Jim Carrey spent Tuesday evening and Wednesday morning tweeting about his anti-vaccination views, and on Thursday night he apologized for including a photo of a young boy without permission. The actor had sent out an image of the boy, who has autism, as part of a series of tweets challenging a new California law that eliminates personal-belief exemptions for childhood immunizations. The mother of Alex Echols asked Carrey to remove the photo of her son, noting that he had not been given permission to use it. @JimCarrey Please remove this photo of my son. You do not have permission to use his image.— Karen Echols (@k...
Source: Healthy Living - The Huffington Post - July 3, 2015 Category: Consumer Health News Source Type: news
Jim Carrey Apologizes For Tweeting Photo Of Boy With Autism In Anti-Vaccine Rant
Jim Carrey spent Tuesday evening and Wednesday morning tweeting about his anti-vaccination views, and on Thursday night he apologized for including a photo of a young boy without permission.
The actor had sent out an image of the boy, who has autism, as part of a series of tweets challenging a new California law that eliminates personal-belief exemptions for childhood immunizations.
The mother of Alex Echols asked Carrey to remove the photo of her son, noting that he had not been given permission to use it.
@JimCarrey Please remove this photo of my son. You do not have permission to use his image.— Karen Echols (@k...
Source: Healthy Living - The Huffington Post - July 3, 2015 Category: Consumer Health News Source Type: news
Jim Carrey Apologizes For Tweeting Photo Of Boy With Autism In Anti-Vaccine Rant
Jim Carrey spent Tuesday evening and Wednesday morning tweeting about his anti-vaccination views, and on Thursday night he apologized for including a photo of a young boy without permission. The actor had sent out an image of the boy, who has autism, as part of a series of tweets challenging a new California law that eliminates personal-belief exemptions for childhood immunizations. The mother of Alex Echols asked Carrey to remove the photo of her son, noting that he had not been given permission to use it. @JimCarrey Please remove this photo of my son. You do not have permission to use his image.— Karen Echols (@k...
Source: Science - The Huffington Post - July 3, 2015 Category: Science Source Type: news
May highlights: Overcoming brain hemorrhage, brachial plexus + more
Catch up on what you may have missed on Thriving last month. Our staff takes a look back at a few of this month’s favorite posts.
A sister’s words: The athlete who couldn’t be tamed by a brain hemorrhage
Carly is a superstar athlete, running a 5:32 mile at the young age of 14. Her heroes include Tom Brady, Malcolm Butler and Boston Children’s neurosurgeon Dr. Ed Smith. After emergency surgery to repair a brain hemorrhage Carly’s career aspirations have shifted, and the Cape Cod track star is now pondering the world of neurosurgery. Read A sister’s words: The athlete who couldn’t be ta...
Source: Thrive, Children's Hospital Boston - June 1, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Our patients’ stories brachial plexus brain hemorrhage melanoma tuberous sclerosis Source Type: news
Tuberous sclerosis: Clinical trial may be what halted Charlotte’s seizures
Charlotte with Jurriaan Peters, MD, in the Clinical and Translational Study Unit.
When Charlotte D’Amario was about 4½ months old, she began making odd, forward-lurching movements. At first, her pediatrician thought it was reflux—that she was trying to spit up. “It was getting worse and worse, and no one had a clue as to what it was,” says Allyson, her mother.
Her parents started to videotape her while she made these odd motions. They occurred in clusters of as many as 50 at a time, several times a day. Seeing videos of Charlotte at 8½ months, her pediatrician sent her to a neurologist. An electroencephalogram (E...
Source: Thrive, Children's Hospital Boston - May 15, 2015 Category: Pediatrics Authors: Nancy Fliesler Tags: All posts Diseases & conditions Our patients’ stories Research Tests & treatment epilepsy seizures TSC tuberous sclerosis complex Source Type: news
Poirot's David Suchet reveals fight for NHS drugs to help grandson
The TV star has criticised 'disorganisation' in the NHS for slowing down the process for better treatment for his grandson, Todd, who has the rare condition Tuberous Sclerosis Complex. (Source: the Mail online | Health)
Source: the Mail online | Health - April 2, 2015 Category: Consumer Health News Source Type: news
133 Organizations Ask Congress to Close the Innovation Deficit
Dear Member of Congress:
The 133 undersigned national business, higher education, scientific, patient, and other organizations write to strongly urge you to pass an omnibus FY2015 appropriations bill this year that includes increased investments in scientific research and higher education needed to help close our nation's innovation deficit.
Members of the Senate and House from both political parties have highlighted the need to address the innovation deficit. Congress has already taken some preliminary steps in this direction. In most instances, individual appropriations bills considered by the House and Senate Appropri...
Source: ActionBioscience - November 12, 2014 Category: Biology Authors: Julie Palakovich Carr Source Type: news
133 Organizations Ask Congress to Close the Innovation Deficit
Dear Member of Congress:
The 133 undersigned national business, higher education, scientific, patient, and other organizations write to strongly urge you to pass an omnibus FY2015 appropriations bill this year that includes increased investments in scientific research and higher education needed to help close our nation's innovation deficit.
Members of the Senate and House from both political parties have highlighted the need to address the innovation deficit. Congress has already taken some preliminary steps in this direction. In most instances, individual appropriations bills considered by the House and Senate Appropri...
Source: ActionBioscience - November 12, 2014 Category: Science Authors: Julie Palakovich Carr Source Type: news
133 Organizations Ask Congress to Close the Innovation Deficit
Dear Member of Congress:
The 133 undersigned national business, higher education, scientific, patient, and other organizations write to strongly urge you to pass an omnibus FY2015 appropriations bill this year that includes increased investments in scientific research and higher education needed to help close our nation's innovation deficit.
Members of the Senate and House from both political parties have highlighted the need to address the innovation deficit. Congress has already taken some preliminary steps in this direction. In most instances, individual appropriations bills considered by the House and Senate Appropri...
Source: ActionBioscience - November 11, 2014 Category: Biology Authors: Julie Palakovich Carr Source Type: news
Self-injury and aggression in tuberous sclerosis complex: cross syndrome comparison and associated risk markers - Eden KE, de Vries PJ, Moss J, Richards C, Oliver C.
BACKGROUND: Research reporting prevalence rates of self-injurious and aggressive behaviour in people with tuberous sclerosis complex (TSC) is limited. No studies have compared rates of these behaviours in TSC with those in other syndrome groups matched for... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 17, 2014 Category: Global & Universal Tags: Age: Adolescents Source Type: news
Sunlight exposure may cause skin tumour development in TSC
UV rays in sunlight cause DNA damage and sun exposure is a major risk factor in most skin cancers. A recent study from Harvard suggests that sun exposure may also worsen the number and severity of skin lesions found in tuberous sclerosis patients (Tyburczy et al., 2013)12/23/2013 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - December 23, 2013 Category: Cancer & Oncology Source Type: news
