Cardiac tumours
Cardiac tumours are most often secondaries from malignancies of breast, lung or malignant melanoma. Primary tumours of the heart are most often benign, of which about half are myxomas. Malignant primary tumours of the heart contribute to about a quarter of the primary cardiac tumours. The commonest primary malignant tumour of the heart would be a sarcoma [1]. Cardiac tumours may present with cardiovascular or constitutional symptoms. Sometimes they are incidentally detected on echocardiography or other imaging modalities.
Left atrial myxoma on echocardiogram
Computed tomography and magnetic resonance imaging can give addi...
Source: Cardiophile MD - August 25, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Fight Aging! Newsletter, December 2nd 2019
In conclusion, T2D impairs vascular function by dysregulated autophagy. Therefore, autophagy could be a potential target for overcoming diabetic microvascular complications.
To What Degree Does Loss of Skeletal Muscle with Age Contribute to Immunosenescence?
https://www.fightaging.org/archives/2019/11/to-what-degree-does-loss-of-skeletal-muscle-with-age-contribute-to-immunosenescence/
Sarcopenia, the progressive loss of muscle mass and strength, is characteristic of aging. A perhaps surprisingly large fraction of the losses can be averted by strength training, but there are nonetheless inexorable proces...
Source: Fight Aging! - December 1, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Topical Rapamycin Evaluated as a Treatment for Skin Aging
This study demonstrates a clear impact of rapamycin treatment on both the molecular signature associated with senescence and the clinical signs of aging in the skin. These data support the idea that a reduction in the burden of senescent cells underlies these improvements. The results could reflect a modification of the senescent cells present in the skin or a reduction in the number of senescent cells. Although rapamycin has been shown to reduce pro-inflammatory secretions produced by senescent cells, the fact that p16INK4A is reduced suggests that the absolute number of senescent cells in the epidermis is reduced. This i...
Source: Fight Aging! - November 26, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Tuberous Sclerosis : Case Report
DiscussionTuberous sclerosis is an autosomal dominant neurocutaneous syndrome characterized by various abnormalities, including multisystemic hamartomas. Also known as Bourneville disease, named after D ésiré-Magloire Bourneville, the French physician who discovered the potato like appearance of cortical lesions in the brains of patients with this condition.Tuberous sclerosis is the second most common phakomatosis behind neurofibromatosis type 1. It has a prevalence estimated to be 1 in 6000. App roximately one third of cases of tuberous sclerosis are familial the other two thirds of cases are sporadic and due to spontan...
Source: Sumer's Radiology Site - July 12, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Funtabulously Frivolous Friday Five 222
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 222.
Question 1
What was the Great Singapore Penis Panic of 1967 all about?
+ Reveal the Funtabulous Answer
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The false belief one’s male appendage was shrinki...
Source: Life in the Fast Lane - January 19, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five barbie burbulance great singapore penis panic haemorrhoids hypoparathyroidism angiomas Intracranial calcification koro Midge pregnancy ring of fire tuberous sclerosis Source Type: blogs
Why does hair turn gray?
Follow me on Twitter @RobShmerling
If you look at photos of President Obama taken before he ran for president and since he left office, you’ll notice a distinct difference: where there used to be only dark brown hair, there is now far more gray than brown. It seems that the stress of running a country would turn any person’s hair gray. But is stress really to blame? And why does hair turn gray, even for those of us who don’t have jobs quite as stressful as President of the United States?
Stress doesn’t actually turn hair gray. In fact, hair doesn’t actually “turn” gray. Once a hair follicle produces hair, the...
Source: Harvard Health Blog - September 18, 2017 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Healthy Aging Skin and Hair Care Source Type: blogs
Obstruction of Magendie's Foramen :MRI
Case Report : A 33-year-old woman presented with visual disturbance and balance difficulty on MRI brain shows dilatation of lateral, III and IV ventricles along with periventricular T2/FLAIR hyperintensity. Temporal horns are dilated. Fourth ventricle appears dilated out of propotion along with prominent CSF flow void in the IV ventricle and some enhancement in ependymal surface of IV ventricle. Contour abnormality in the foramen of magendie. These findings are indicative of IV ventricular outflow tract obstruction possibly post infective sequele/arachnoiditis in foramen of magendieTeaching Points:Memb...
Source: Sumer's Radiology Site - September 7, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Neuropathology History: D ésiré Magloire Bourneville (1840-1909)
D ésiré Magloire Bourneville (1840-1909)Born in Garenci éres, France. From 1905 until his death, Bourneville headed the Foundation Vallée for the Study of Feebleminded Children. " Was recognized as the leading continental authority on all aspects of mental abnormality of children. Most of his neuropathologic work was onidiocy. His description of tuberous sclerosis, since known as Bourneville ' s disease, appeared in 1880. "Source: Haymaker, Webb (Army Institute of Pathology). Guide to the exhibit on the history of neuropathology. Presented at the annual meetings of the American Psychiatric Association (Washington...
Source: neuropathology blog - December 7, 2016 Category: Radiology Tags: history Source Type: blogs
A doctor turns to social media for organ donation
A guest column by the American College of Physicians, exclusive to KevinMD.com.
A couple of months ago I received a Facebook invitation to “like” a page. That was not unusual, and usually the pages are on silly or obscure topics, but this page was different. The name of the page was New Kidney for Stu.
Stuart Himmelstein, MD, FACP, is one of my Facebook friends. Stu is a solo internist in private practice in Delray Beach, Florida. He is also a past Governor of the Florida Chapter of the American College of Physicians (ACP), which is how I met and got to know him. His ACP service is just one of his many contributions to...
Source: Kevin, M.D. - Medical Weblog - July 29, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/yul-ejnes" rel="tag" > Yul Ejnes, MD < /a > Tags: Physician Nephrology Source Type: blogs
Better Understanding the Role of p53 in Cancer
The gene p53 is an important tumor suppressor. A loss of function in p53 is involved in many cancers, permitting uncontrolled replication of cells. Here researchers make progress in understanding how this works under the hood, finding links that may help to provide a detail view of how rapamycin and a few other drugs act to reduce cancer risk.
The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function. New research describes how mutations and or loss of function of t...
Source: Fight Aging! - December 15, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Relationship between Hamartoma and Cancer
In June, 2014, my book, entitled Rare Diseases and Orphan Drugs: Keys to Understanding and Treating the Common Diseases was published by Elsevier. The book builds the argument that our best chance of curing the common diseases will come from studying and curing the rare diseases. The book has an extensive glossary, that explains the meaning and relevance of medical terms appearing throughout the chapters. The glossary can be read as a stand-along document. Here is an example of one term, "hamartoma", excerpted from the glossary.Hamartoma - Hamartomas are benign tumors that occupy a peculiar zone lying between neoplasi...
Source: Specified Life - July 15, 2014 Category: Pathologists Tags: cancer types carcinogenesis common cancers disease genes genetic disease hyperplasia orphan disease orphan drugs rare cancers rare disease tissue overgrowth tumor biology tumor types Source Type: blogs
What Rare Diseases Teach Us About the Cellular Basis of Aging
In June, 2014, my book, entitled Rare Diseases and Orphan Drugs: Keys to Understanding and Treating the Common Diseases was published by Elsevier. The book builds the argument that our best chance of curing the common diseases will come from studying and curing the rare diseases. Chapter 4 explains that much what we think we know about the aging process comes from studying rare diseases of premature aging, such as Hutchinson–Gilford progeria syndrome, Bloom syndrome, Werner syndrome, Cockayne syndrome, dyskeratosis congenita, Fanconi anemia, Wolfram syndrome, and xeroderma pigmentosum. Lessons learned from these rare...
Source: Specified Life - July 4, 2014 Category: Pathologists Tags: ageing aging biology of aging cancer cause of aging cell renewal common disease genetic disease orphan disease orphan drugs rare disease Source Type: blogs
Selecting Straightforward Products For multiple sclerosis
* Corrects ѕkeletal misalignments – relieves back pain, sciatica, and TϺJ syndrome. A ρrognosis of multiple sclerosis survival rate is about 35 years. Ӏ am going to go all zen on you and juѕt tell yοu “it is what it is”. Tuberous sclerosis, or tuberous ѕclerosis complex (TSC) is a rare, multіsystem genetiс disease that [...] (Source: Carin' For Karen)
Source: Carin' For Karen - December 24, 2013 Category: Cancer Authors: KelvinCezbgu Tags: Life in general Source Type: blogs
USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics.
Feature
Disease
45, X chromosome
Turner’s syndrome
5-HIAA increased in urine
Carcinoid syndrome
Aganglionic rectum
Hirschsrpung’s disease
Apple-core sign on barium enema
Colon cancer
Arched back (opisthotonos)
Tetanus
Argyll-Robertson pupil
Syphilis
Ash leaf on forehead
Tuberous sclerosis
Auer rods
Acute myelogenous leukemia
Austin Flint murmur
Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs
