Researchers Generate Thyroid Organoids Capable of Restoring Function in Mice
When building functional organ tissue from the starting point of pluripotent stem cells, a different recipe is required for each different tissue type. Good progress is being made in establishing these recipes, and over the past decade the research community has steadily expanded the number of organs for which tissue engineered organoids can be constructed. An organoid is a millimeter-scale segment of functional organ tissue, only lacking the blood vessel network needed to support larger structures. Organoids are very useful in research, but in many cases can also be used to restore lost organ function when transplanted in...
Source: Fight Aging! - March 22, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What ’ s with low free T3 thyroid hormone levels?
The post What’s with low free T3 thyroid hormone levels? appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - March 6, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle free t3 low t3 Thyroid undoctored Source Type: blogs
Iodine deficiency: The forgotten public health crisis
The post Iodine deficiency: The forgotten public health crisis appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - February 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle Thyroid undoctored Weight Loss Source Type: blogs
The Art of Prescribing (Or Not)
By HANS DUVEFELT
I have learned a few things about prescribing medications during my 42 years as a physician. Some are old lessons, and some are more recent. I thought I’d share some random examples.
First: I don’t like to have to use medications, but when they seem necessary, I choose, present and prescribe them with great care.
CHOOSING MEDICATIONS
Medications are like people. They have personalities. With so many choices for any given diagnosis or symptom, I consider their mechanism of action, possible beneficial additional effects and their risk of unwanted side effects when selecting which one to presc...
Source: The Health Care Blog - February 1, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Hans Duvefelt Source Type: blogs
February 2021: Clinical Presentation Provides Clue to Toxicity
A 43-year-old man with a history of bipolar disorder, hypertension, and asthma presented with altered mental status and a tremor. He reported increasing fatigue and hand tremors for one day. He said he and his family recently had food poisoning with vomiting and diarrhea for several days. Those symptoms had resolved. He continued to take all of his prescribed medications, which included lithium carbonate (Lithobid) 800 mg BID and amlodipine 10 mg daily.His initial vital signs were a heart rate of 104 bpm, a blood pressure of 136/82 mm Hg, a respiratory rate of 16 bpm, an oxygen saturation of 99% on room air, and a temperat...
Source: The Tox Cave - January 29, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Sarah ’ s Wheat Belly health and life transformation
Sarah’s story reminds us how the simple matter of diet can shape our lives for decades, affecting energy, body weight, emotional health–just about every aspect of our physical and social lives before we finally stumble on the right answers. After many years of struggling with poor health, relying on prescription medications that never addressed underlying causes, it therefore came as a surprise to Sarah that she could indeed achieve magnificent health without the drugs by simply following the diet programmed into human genetic code and supplementing nutrients that are deficient in modern life.
...
Source: Wheat Belly Blog - January 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free Inflammation joint pain wheat belly Source Type: blogs
CBD and other medications: Proceed with caution
Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.
Doubling up on side effects
While generally considered safe...
Source: Harvard Health Blog - January 11, 2021 Category: Consumer Health News Authors: Katsiaryna Bykov, PharmD, ScD Tags: Drugs and Supplements Marijuana Medical Research Safety Source Type: blogs
Fight Aging! Newsletter, December 14th 2020
In conclusion, aging alters the cerebral vasculature to impair mitochondrial function and mitophagy and increase IL-6 levels. These alterations may impair BBB integrity and potentially reduce cerebrovascular health with aging.
Senescent Cells Fail to Maintain Proteostasis
https://www.fightaging.org/archives/2020/12/senescent-cells-fail-to-maintain-proteostasis/
Given the newfound consensus in the research community regarding the importance of senescent cells to degenerative aging, it isn't surprising to see a great deal more fundamental research into the biochemistry of cellular senescence now taking pl...
Source: Fight Aging! - December 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Connected Age-Related Atrophy of Thymus and Pineal Gland
Decades ago, the pineal gland was the focus of a great deal of ignorant hype regarding research into aging and the prospects for treating aging. The paper here is an interesting overview of what is known about possible connections between the thymus and the pineal gland, both of which atrophy with age, and both of which have sweeping effects on the immune system. It is perhaps of greatest interest as a catalog of things yet to be discovered - roads leading into the dark forest from the starting point of lists of molecules secreted by thymus and pineal gland, added to what is known of what goes on inside these two organs, a...
Source: Fight Aging! - December 9, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Amiodarone – class IIIa
Amiodarone is designated as class IIIa antiarrhythmic agent in the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. This is the group of voltage dependent K+ channel blockers. It is a nonselective K+ channel blocker. Another drug in class IIIa is dronedarone, which is a related drug free of iodine atoms and hence the thyroid related adverse effects of amiodarone.
Amiodarone is useful in wide range of atrial and ventricular arrhythmias and it is a so called broad spectrum antiarrhythmic agent and widely used.
Amiodarone prolongs QTc, but torsades des pointes is rare, possibly due to its effects on other cha...
Source: Cardiophile MD - October 15, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: ECG / Electrophysiology Polysorbate and hypotension with amiodarone Source Type: blogs
Treating mild hypothyroidism: Benefits still uncertain
Your thyroid, a tiny, butterfly-shaped gland located in front of your windpipe (trachea) and below your voice box (larynx) can have a profound impact on your health and well-being. Throughout life, your thyroid is constantly producing hormones that influence your metabolism. These hormones affect your mood, energy, body temperature, weight, heart, and more.
A brief overview of hypothyroidism
Your thyroid produces two kinds of thyroid hormones: T4, or thyroxine, and T3, or triiodothyronine. These hormones influence every cell, tissue, and organ in your body, from your muscles, bones, and skin to your digestive tract, brain,...
Source: Harvard Health Blog - September 28, 2020 Category: Consumer Health News Authors: Jeffrey Garber, MD, FACP, MACE Tags: Drugs and Supplements Heart Health Thyroid Disorders Source Type: blogs
Post #52 Overkill: When Modern Medicine Goes Too Far by Paul Offit M.D.
Overkill: When Modern Medicine Goes Too Far by Paul Offit M.D.I am admittedly a huge fanboy of Paul Offit, an infectious disease guru at Children ' s Hospital of Philadelphia, one of the preeminent pediatric hospitals in the world. His latest bookOverall: When Modern Medicine Goes Too Far, is a collection of medical facts that are already known to the well-read individual, but fly in the face of wrongly-held, out-dated, commonly-believed medical concepts. The majority of the incorrect information was previously considered the standard of care, but newer and better science and studies have clearly demonstrate...
Source: A Pediatrician's Blog - September 23, 2020 Category: Pediatrics Source Type: blogs
Cough and cold season is arriving: Choose medicines safely
With the summer winding down and fall moving in, colder weather will arrive soon — along with cold and flu season. Millions of Americans get the common cold each year, often more than once. To counter coughs and runny noses, many will turn to over-the-counter (OTC) medications available for relief without a prescription.
Heading to the pharmacy for some relief? Read this first
While OTC medicines do not cure or shorten the common cold or flu, they can ease some symptoms. Finding a product that fits your needs, however, may not be so straightforward. A recent study evaluated brand-name OTC medications marketed as cold, al...
Source: Harvard Health Blog - September 22, 2020 Category: Consumer Health News Authors: Katsiaryna Bykov, PharmD, ScD Tags: Cold and Flu Drugs and Supplements Health Infectious diseases Source Type: blogs
EchoNous KOSMOS 3-in-1 Ultrasound, Electronic Stethoscope, and ECG Helps with COVID-19
EchoNous, a developer of novel ultrasounds, has found a way to leverage multiple critical clinical technologies within a single device. The result is KOSMOS, a handheld 3-in-1 device consisting of an ultrasound, electronic stethoscope, and an ECG, all linked via artificial technology.
When COVID-19 was hitting NYC earlier this year, EchoNous was able to use KOSMOS to help diagnose COVID patients and to inform on treatment strategies. We had a lovely chat with Dr. Richard Hoppmann, a key member of EchoNous, Clinical Professor of Internal Medicine at the University of South Carolina, and the Director of the Ultrasound I...
Source: Medgadget - September 21, 2020 Category: Medical Devices Authors: Alice Ferng Tags: Cardiology Critical Care Diagnostics Exclusive Informatics Medicine Public Health Source Type: blogs
Thyroid acropachy: an unusual complication of Graves disease
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - August 12, 2020 Category: Internal Medicine Tags: allergy and immunology dermatology endocrinology Source Type: blogs
