Swine Flu (H1N1) Vaccine Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

VISN: virus instance segmentation network for TEM images using deep attention transformer
Brief Bioinform. 2023 Sep 22;24(6):bbad373. doi: 10.1093/bib/bbad373.ABSTRACTThe identification of viruses from negative staining transmission electron microscopy (TEM) images has mainly depended on experienced experts. Recent advances in artificial intelligence have enabled virus recognition using deep learning techniques. However, most of the existing methods only perform virus classification or semantic segmentation, and few studies have addressed the challenge of virus instance segmentation in TEM images. In this paper, we focus on the instance segmentation of severe acute respiratory syndrome coronavirus type 2 (SARS-...
Source: Briefings in Bioinformatics - October 30, 2023 Category: Bioinformatics Authors: Chi Xiao Jun Wang Shenrong Yang Minxin Heng Junyi Su Hao Xiao Jingdong Song Weifu Li Source Type: research

Quadrivalent neuraminidase RNA particle vaccine protects pigs against homologous and heterologous strains of swine influenza virus infection
This study evaluated the immunogenicity and efficacy of an adjuvanted, quadrivalent RNA Particle vaccine (Sequivity NA), currently licensed as Sequivity® IAV-S NA. This vaccine was formulated based on four NA antigens representing the major NA clades of IAV subtypes H1N1, H1N2 and H3N2 circulating in swine herds in the United States. In a series of trials, pigs were vaccinated twice, at three days and three weeks of age (WOA), followed by challenge with either homologous or heterologous IAV strains at 8 or 15 WOA. The Sequivity NA vaccine induced robust serum NA inhibition (NI) antibody and protected against IAV-S strains...
Source: Vaccine - October 26, 2023 Category: Allergy & Immunology Authors: Pravina Kitikoon Susan M Knetter Mark A Mogler Chandra L Morgan Allison Hoehn Supraja Puttamreddy Erin L Strait Ruud P A M Segers Source Type: research

Safety and Benefits of COVID-19 Vaccination in Pregnancy —Implications for the Maternal Vaccination Platform
The development of safe and effective vaccines against the novel SARS-CoV-2 virus, the cause of COVID-19 pandemic, was justifiably hailed as a major advance in protecting the population against severe and fatal infection. The vaccine rollout was targeted toward recognized communities at risk, including older adults, those with comorbidities, and those who were immunosuppressed. Pregnant women, and by extension, their infants, were included in these high-risk groups for vaccination. The prioritization of pregnant women was justified from historical observations of disproportionate mortality and morbidity during previous inf...
Source: JAMA Pediatrics - October 23, 2023 Category: Pediatrics Source Type: research

Introducing seasonal influenza vaccine in Bhutan: Country experience and achievements
Vaccine. 2023 Oct 20:S0264-410X(23)01255-0. doi: 10.1016/j.vaccine.2023.10.053. Online ahead of print.ABSTRACTBhutan successfully introduced multiple vaccines since the establishment of the Vaccine Preventable Disease Program in 1979. Surveillance and subsequent introduction of influenza vaccination became a public health priority for the Ministry of Health following the influenza A(H1N1)pdm09 pandemic. Sentinel surveillance for influenza in Bhutan began in 2008, and a study of severe acute respiratory infection was conducted in 2017, which found the highest influenza burden in children aged <5 years and adults ≥50 ye...
Source: Vaccine - October 22, 2023 Category: Allergy & Immunology Authors: Sonam Wangchuk Aslesh O Prabhakaran Guru Prasad Dhakal Cheten Zangmo Radhika Gharpure Tashi Dawa Sangay Phuntsho Britni Burkhardsmeier Siddhartha Saha Dechen Wangmo Kathryn E Lafond Source Type: research

Heterologous prime-boost H1N1 vaccination exacerbates disease following challenge with a mismatched H1N2 influenza virus in the swine model
Influenza A viruses (IAVs) pose a significant threat to both human and animal health. Developing IAV vaccine strategies able to elicit broad heterologous protection against antigenically diverse IAV strains is pivotal in effectively controlling the disease. The goal of this study was to examine the immunogenicity and protective efficacy of diverse H1N1 influenza vaccine strategies including monovalent, bivalent, and heterologous prime-boost vaccination regimens, against a mismatched H1N2 swine influenza virus. Five groups were homologous prime-boost vaccinated with either an oil-adjuvanted whole-inactivated virus (WIV) mon...
Source: Frontiers in Immunology - October 20, 2023 Category: Allergy & Immunology Source Type: research

Viruses, Vol. 15, Pages 2035: Clinical Features and Outcomes of the Association of Co-Infections in Children with Laboratory-Confirmed Influenza during the 2022 & ndash;2023 Season: A Romanian Perspective
In conclusion, co-infections with respiratory viruses increase the disease severity of the pediatric population to influenza, especially among young children who are more vulnerable to developing a serious illness. We recommend that all people above the age of six months should receive vaccinations against influenza to prevent the illness and its severe complications. (Source: Viruses)
Source: Viruses - September 30, 2023 Category: Virology Authors: M ădălina-Maria Merișescu Monica Lumini ța Luminos Carmen Pavelescu Gheorghi ţă Jugulete Tags: Article Source Type: research

Viruses, Vol. 15, Pages 2030: Sequence-Based Antigenic Analyses of H1 Swine Influenza A Viruses from Colombia (2008 & ndash;2021) Reveals Temporal and Geographical Antigenic Variations
This study provides information about FLUAV variability in pigs under natural conditions in the absence of vaccination and emphasizes the need for surveillance of its phylogenetic and antigenic characteristics. (Source: Viruses)
Source: Viruses - September 30, 2023 Category: Virology Authors: Andres F. Ospina-Jimenez Arlen P. Gomez Maria A. Rincon-Monroy Lucia Ortiz Daniel R. Perez Mario Pe ña Gloria Ramirez-Nieto Tags: Article Source Type: research

Association of vaccine-specific regulatory T cells with reduced antibody response to repeated influenza vaccination
This article is protected by copyright. All rights reserved.PMID:37713727 | DOI:10.1002/eji.202350525 (Source: European Journal of Immunology)
Source: European Journal of Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Pin-Hung Lin Po-Ju Hsiao Ching-Fu Pan Ming-Tsan Liu Jann-Tay Wang Chi Ching Fang-Yi Wu Yi-Hsuan Lin Yu-Chan Yang Le-Yin Hsu Hung-Chih Yang Un-In Wu Source Type: research

Association of vaccine-specific regulatory T cells with reduced antibody response to repeated influenza vaccination
This article is protected by copyright. All rights reserved.PMID:37713727 | DOI:10.1002/eji.202350525 (Source: Cancer Control)
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Pin-Hung Lin Po-Ju Hsiao Ching-Fu Pan Ming-Tsan Liu Jann-Tay Wang Chi Ching Fang-Yi Wu Yi-Hsuan Lin Yu-Chan Yang Le-Yin Hsu Hung-Chih Yang Un-In Wu Source Type: research