Validation of prognostic stroke scores —comments on “Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort”: Author’s response
(Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 2, 2024 Category: Neurosurgery Source Type: research

Effect of Statin Treatment in Patients with Aneurysmal Subarachnoid Hemorrhage: A Network Meta-Analysis
ConclusionsSimvastatin 80 mg might be the most effective intervention in reducing DCI. Additionally, short-term therapy might provide more benefits. Further research with longer follow-up is warranted to validate the current findings in patients with aSAH who are at high risk of DCI. (Source: Neurocritical Care)
Source: Neurocritical Care - April 2, 2024 Category: Neurology Source Type: research

Validation of prognostic stroke scores —comments on “Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort”: Author’s response
(Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 2, 2024 Category: Neurosurgery Source Type: research

Development of a 3D Brain Model to Study Sex-Specific Neuroinflammation After Hemorrhagic Stroke
Transl Stroke Res. 2024 Apr 1. doi: 10.1007/s12975-024-01243-y. Online ahead of print.ABSTRACTSubarachnoid hemorrhage (SAH) accounts for 5% of stroke, with women having a decreased inflammatory response compared to men; however, this mechanism has yet to be identified. One hurdle in SAH research is the lack of human brain models. Studies in murine models are helpful, but human models should be used in conjunction for improved translatability. These observations lead us to develop a 3D system to study the sex-specific microglial and neuroglial function in a novel in vitro human SAH model and compare it to our validated in v...
Source: Cell Research - April 1, 2024 Category: Cytology Authors: Rezwanul Islam Hadi Hasan Choudhary Hritik Mehta Feng Zhang Tudor G Jovin Khalid A Hanafy Source Type: research

Pathogenesis and management of low-pressure hydrocephalus: A narrative review
Patients diagnosed with low-pressure hydrocephalus typically present with enlarged ventricles and unusually low intracranial pressure, often measuring below 5 cmH2O or even below atmospheric pressure. This atypical presentation often leads to low recognition and diagnostic rates. The development of low-pressure hydrocephalus is believed to be associated with a decrease in the viscoelasticity of brain tissue or separation between the ventricular and subarachnoid spaces. Risk factors for low-pressure hydrocephalus include subarachnoid hemorrhage, aqueduct stenosis, prior cranial radiotherapy , ventricular shunting, and cer...
Source: Journal of the Neurological Sciences - April 1, 2024 Category: Neurology Authors: Shanshan Duan, Jin Hu Tags: Review Article Source Type: research

Pressure for change: can we continue to ignore the lack of evidence for blood pressure augmentation to treat delayed neurological deficit following subarachnoid haemorrhage?
(Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 1, 2024 Category: Intensive Care Authors: Ronan O ’Leary, Jonathan P. Coles and Lara Prisco Tags: Editorial Notes Source Type: research

Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease
CONCLUSION: This investigation has pinpointed particular strains of gut microbiota that play protective or detrimental roles in cerebrovascular disease pathogenesis. These findings offer valuable insights that could be pivotal for the clinical management, prevention, and treatment of cerebrovascular diseases.PMID:38551043 | DOI:10.2174/0115672026299307240321090030 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 29, 2024 Category: Neurology Authors: Shihang Luo Rui Mao Yi Li Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease
CONCLUSION: This investigation has pinpointed particular strains of gut microbiota that play protective or detrimental roles in cerebrovascular disease pathogenesis. These findings offer valuable insights that could be pivotal for the clinical management, prevention, and treatment of cerebrovascular diseases.PMID:38551043 | DOI:10.2174/0115672026299307240321090030 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 29, 2024 Category: Neurology Authors: Shihang Luo Rui Mao Yi Li Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease
CONCLUSION: This investigation has pinpointed particular strains of gut microbiota that play protective or detrimental roles in cerebrovascular disease pathogenesis. These findings offer valuable insights that could be pivotal for the clinical management, prevention, and treatment of cerebrovascular diseases.PMID:38551043 | DOI:10.2174/0115672026299307240321090030 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 29, 2024 Category: Neurology Authors: Shihang Luo Rui Mao Yi Li Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease
CONCLUSION: This investigation has pinpointed particular strains of gut microbiota that play protective or detrimental roles in cerebrovascular disease pathogenesis. These findings offer valuable insights that could be pivotal for the clinical management, prevention, and treatment of cerebrovascular diseases.PMID:38551043 | DOI:10.2174/0115672026299307240321090030 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - March 29, 2024 Category: Neurology Authors: Shihang Luo Rui Mao Yi Li Source Type: research

Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research

NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - March 28, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research