Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Surgical intervention for cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: a systematic review
CONCLUSIONS: Surgery in CAA-related ICH is safe with no substantial IOH, POH, and early recurrent hemorrhage risk. Outcome appears to be poor, however, especially in older patients, although good quality of evidence is lacking. Patients with CAA should not be excluded from ongoing surgery RCTs in ICH to enable future subgroup analysis of this specific patient population.PMID:38579346 | DOI:10.3171/2024.1.JNS231852 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Ole F de Bruin Sabine Voigt Jan W Schoones Wouter A Moojen Ellis S van Etten Marieke J H Wermer Source Type: research

Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Surgical intervention for cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: a systematic review
CONCLUSIONS: Surgery in CAA-related ICH is safe with no substantial IOH, POH, and early recurrent hemorrhage risk. Outcome appears to be poor, however, especially in older patients, although good quality of evidence is lacking. Patients with CAA should not be excluded from ongoing surgery RCTs in ICH to enable future subgroup analysis of this specific patient population.PMID:38579346 | DOI:10.3171/2024.1.JNS231852 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Ole F de Bruin Sabine Voigt Jan W Schoones Wouter A Moojen Ellis S van Etten Marieke J H Wermer Source Type: research

Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Surgical intervention for cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: a systematic review
CONCLUSIONS: Surgery in CAA-related ICH is safe with no substantial IOH, POH, and early recurrent hemorrhage risk. Outcome appears to be poor, however, especially in older patients, although good quality of evidence is lacking. Patients with CAA should not be excluded from ongoing surgery RCTs in ICH to enable future subgroup analysis of this specific patient population.PMID:38579346 | DOI:10.3171/2024.1.JNS231852 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Ole F de Bruin Sabine Voigt Jan W Schoones Wouter A Moojen Ellis S van Etten Marieke J H Wermer Source Type: research

Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Surgical intervention for cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: a systematic review
CONCLUSIONS: Surgery in CAA-related ICH is safe with no substantial IOH, POH, and early recurrent hemorrhage risk. Outcome appears to be poor, however, especially in older patients, although good quality of evidence is lacking. Patients with CAA should not be excluded from ongoing surgery RCTs in ICH to enable future subgroup analysis of this specific patient population.PMID:38579346 | DOI:10.3171/2024.1.JNS231852 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Ole F de Bruin Sabine Voigt Jan W Schoones Wouter A Moojen Ellis S van Etten Marieke J H Wermer Source Type: research

Rates of operative intervention and in-hospital mortality following subarachnoid hemorrhage in patients with COVID-19
CONCLUSIONS: COVID-19 had significant impacts on patients with nontraumatic SAH. Specifically, patients with COVID-19 were significantly less likely to undergo surgery and had higher in-hospital mortality rates; however, for patients who did undergo procedural intervention, there was no significant difference in the type of intervention. Multiple factors, from medical acuity to healthcare system limitations, may contribute to these findings. Further retrospective research is needed to identify both specific causes of lower intervention rates and other potential nonaneurysmal causes of SAH in patients with COVID-19.PMID:385...
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Jonathan Dallas Benjamin Fixman Li Ding Michelle Lin Vincent N Nguyen Frank J Attenello William J Mack Source Type: research

Surgical intervention for cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: a systematic review
CONCLUSIONS: Surgery in CAA-related ICH is safe with no substantial IOH, POH, and early recurrent hemorrhage risk. Outcome appears to be poor, however, especially in older patients, although good quality of evidence is lacking. Patients with CAA should not be excluded from ongoing surgery RCTs in ICH to enable future subgroup analysis of this specific patient population.PMID:38579346 | DOI:10.3171/2024.1.JNS231852 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 5, 2024 Category: Neurosurgery Authors: Ole F de Bruin Sabine Voigt Jan W Schoones Wouter A Moojen Ellis S van Etten Marieke J H Wermer Source Type: research

Clinical characteristics of aneurysmal subarachnoid haemorrhage complicated by Takotsubo cardiomyopathy resulting in good neurological outcome
. (Source: British Journal of Neurosurgery)
Source: British Journal of Neurosurgery - April 4, 2024 Category: Neurosurgery Authors: Takafumi KawasakiTaishi NakamuraMakoto OhtakeTaisuke AkimotoHiroshi ManakaKoichi HamadaKatsumi SakataMasayuki IwashitaIchiro TakeuchiTetsuya Yamamotoa Department of Emergency and Critical Care, Yokohama City University Medical Center, Yokohama, Japanb Dep Source Type: research

Correction to: ’Roles of Prokineticin 2 in Subarachnoid Hemorrhage-Induced Early Brain Injury via Regulation of Phenotype Polarization in Astrocytes’
(Source: Molecular Neurobiology)
Source: Molecular Neurobiology - April 4, 2024 Category: Neurology Source Type: research

Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage
CONCLUSION: Neuritin alleviated EBI by restoring impaired autophagic flux after SAH through the regulation of the cGAS-STING pathway.PMID:38570154 | DOI:10.1016/j.brainres.2024.148909 (Source: Brain Research)
Source: Brain Research - April 3, 2024 Category: Neurology Authors: Hao Zhang Kunhao Ren Youjie Hu Bin Liu Yaowen He Hui Xu Ketao Ma Weidong Tian Linzhi Dai Dong Zhao Source Type: research

Neuritin promotes autophagic flux by inhibiting the cGAS-STING pathway to alleviate brain injury after subarachnoid haemorrhage
CONCLUSION: Neuritin alleviated EBI by restoring impaired autophagic flux after SAH through the regulation of the cGAS-STING pathway.PMID:38570154 | DOI:10.1016/j.brainres.2024.148909 (Source: Brain Research)
Source: Brain Research - April 3, 2024 Category: Neurology Authors: Hao Zhang Kunhao Ren Youjie Hu Bin Liu Yaowen He Hui Xu Ketao Ma Weidong Tian Linzhi Dai Dong Zhao Source Type: research