Fight Aging! Newsletter, August 14th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - August 13, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Skin Grafts for Gene Therapy Could Treat Type II Diabetes and Obesity
Scientists at the University of Chicago genetically modified skin cells to produce glucagon-like peptide 1 (GLP1) protein that is beneficial in diabetes and reduces appetite, and these investigators grew the cells in a dish to form a skin graft. The grafts could potentially be used to treat diabetes and obesity, and could provide a new way to perform gene therapy for a variety of diseases.
When normal and gene-altered mice ate the high-fat diet — along with varying levels of doxycycline to induce GLP1 release — mice expressing GLP1 (left) gained less weight gain while normal mice (right) grew fat. Credit: Wu L...
Source: Medgadget - August 4, 2017 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine News Source Type: blogs
A Cellular Approach to a Biomarker of Aging
Researchers here discuss a new cellular approach to building a biomarker of aging, a way to assess the biological age of an individual. In the SENS view of aging as accumulated molecular damage and its secondary consequences, such a biomarker must reflect the current load of damage present in an individual: people with more damage are older and suffer greater degeneration. The true value of a good biomarker of biological age is that it can be used to significantly speed up research and development, in that it will allow potential rejuvenation therapies to be assessed for their ability to turn back aging far more rapidly, c...
Source: Fight Aging! - July 13, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 22nd 2017
In this study, researchers analysed data of millions of British patients between 1995 and 2015 to see if this claim held true. They tracked people who were obese at the start of the study, defined as people with a body mass index (BMI) of 30 or more, who had no evidence of heart disease, high blood pressure, high cholesterol or diabetes at this point. They found these people who were obese but "metabolically healthy" were at higher risk of developing heart disease, strokes and heart failure than people of normal weight.
No such thing as 'fat but fit', major study finds
Several studies in the past have sug...
Source: Fight Aging! - May 21, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Female Cosmetic Genital Surgery: Concepts, Classification and Techniques
Dr. Hamori ' s book is now available from Thieme Medical Publishers and amazon.comFemale Cosmetic Genital Surgery:Concepts, classification and techniques (by Christine A. Hamori, Paul E. Banwell and Red Alinsod) provides a comprehensive guidance for surgeons who perform genital cosmetic treatments for their female patients. It is an invaluable resource with 350 color photos and surgical illustrations, videos and more, with the objective of achieving the best possible outcomes.From the Preface, Dr. Hamori writes …" During the late 1990s, when I was fresh out of my plastic surgery residency, I met a young woman who request...
Source: What's New In Plastic Surgery? - April 11, 2017 Category: Cosmetic Surgery Tags: book boston christine hamori female cosmetic genital surgery labiaplasty Source Type: blogs
Progress in Bioprinting of Vascular Networks
Perhaps the greatest challenge in tissue engineering, and this has been true for a decade now, is creating the necessary networks of blood vessels to support large sections of tissue. The approaches to the problem are no big secret: either print the blood vessels into the tissue structure as it is assembled, or somehow guide cells into doing that job for you. Unfortunately both paths have proven to be far more difficult than anticipated, which is one of the reasons why decellularization of donor organs has received so much attention. In that case, natural vascular network structures already exist and will be recreated much...
Source: Fight Aging! - March 3, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
SkinGun Investigational Therapy for Burns Uses Patients ’ Own Stem Cells for Healing
RenovaCare, a company based in New York City, is seeking FDA approval for the SkinGun, a device to treat burns using a patient’s own stem cells. Significant portions of skin can be destroyed in burn injuries, meaning that regenerative therapy is required to restore or replace the injured tissue. Current treatments for burns involve skin grafting, where healthy skin is removed from the patient and then cultured in a laboratory, sometimes for several weeks, to grow larger sheets of cells. This delay in treatment can sometimes mean that the patient dies or develops complications such as infections.
The SkinGun has been dev...
Source: Medgadget - February 2, 2017 Category: Medical Equipment Authors: Conn Hastings Tags: Genetics Plastic Surgery Source Type: blogs
Bioprinting Human Skin Cuts the Time Needed from Weeks to Minutes
Skin is one of the easier starting points for 3D bioprinting, the application of rapid prototyping technologies to the construction of living tissue. Since skin is a thin tissue, the challenging issue of producing the intricate blood vessel networks needed to supply inner cells with oxygen and nutrients can be skipped. Thin tissue sections can be supported in a suitable nutrient bath, and after transplant, patient blood vessels will grow into the new skin. Further, there is a fairly large and long-established research and development industry involved in various forms of skin regeneration. Numerous forms of prototype skin-...
Source: Fight Aging! - January 25, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Birthing New Skin with Umbilical Cord Stem Cells
Dr. Phan Toan Thang sees “magic” in cord tissue stem cells. The chief scientist’s passion for healing wounds led him to discover a way to create skin cells quickly and in large quantities by using the lining from umbilical cords.
Instead of using the limited amount of skin on a patient’s body to help heal burns, which is a painful and expensive process, the cells from the cord tissue lining provides cells to create new skin, bone, and even other body parts, such as the cornea in the eye. This method of skin growing can heal wounds from burns or diseases such as diabetes.
“Non-healing wounds are a big medi...
Source: Cord Blood News - November 21, 2016 Category: Perinatology & Neonatology Authors: Maze Cord Blood Tags: Cord Tissue medical research stem cells clinical trial mesenchymal stem cells Source Type: blogs
Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!
CONCLUSION:The variables that interplay in cases of severe aortic stenosis are what cause these patients to be so difficult to manage, and specific therapies targeted to fix one issue often worsen the effects of another issue. If someone is in respiratory distress, their airway and breathing needs to be secured, either through non-invasive or invasive means. Next, the patient ’s blood pressure needs to be stabilized. Oftentimes the most appropriate agent will be a positive inotrope, with consideration of a vasoactive agent in persistent hypotension. Once a patient is stabilized, determining the extent of damage to their ...
Source: Dr. Smith's ECG Blog - November 18, 2016 Category: Cardiology Authors: Steve Smith Source Type: blogs
Doctor, take that patient ’s call
As rheumatologists, we pride ourselves on spending time with our patients, listening to their problems and their family’s problems, and answering all of their questions. Whenever my husband and I run into a patient of mine on the street, they always tell him that I am the best doctor ever. In spite of these accolades, I realized recently I was guilty of doing something with a handful of my patients that made me feel somewhat ashamed. It took my recent stint as a patient to make me realize how important such a small thing can be. That small thing being the call from the patient.
A few weeks ago I was diagnosed with sclero...
Source: Kevin, M.D. - Medical Weblog - September 25, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/madelaine-feldman" rel="tag" > Madelaine Feldman, MD < /a > Tags: Physician Cancer Source Type: blogs
Practical and Helpful Tips: Printing
The Future of Printing Technology is 3D Printing
How far do you think can technology evolve? It seems that it can go as far as one can imagine it to be. Today’s technological advances let many of us to relish the convenience and relief it brings. Each year, a new scientific concept is presented to the public where one of them enables the realization of one’s dreams, all because of a 3D printer machine.
Define 3D Printing
3D Printing is the method of printing a thing that can be used by another individual. The process begins simple. You can generate whatever photo you want in a computer software, and once you...
Source: All Kidney News - August 18, 2016 Category: Urology & Nephrology Authors: admin Tags: Relationships Source Type: blogs
Fight Aging! Newsletter, August 1st 2016
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - July 31, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Further Investigation of P21 and SDF-1 Shows that Cxcr4 Inhibitors can Promote Scarless Healing in Mammals
Mice lacking p21 can regenerate small wounds without scarring, something that is not normally possible in adult mammals. Separately, SDF-1 has been identified as a signal to recruit and activate stem cells, and efforts are underway build regenerative therapies on this basis. Here, scientists dig further into the intersection of these two lines of research to find - as in other studies - that immune system involvement seems to be key to the process. They show that an existing class of drug can induce healing of minor injuries without scars in mice by blocking some of the immune cell activities that normally take place in ma...
Source: Fight Aging! - July 25, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
