Fight Aging! Newsletter, August 14th 2017

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents A Novel View of Lysosomal Dysfunction in Neurodegenerative Disease Cardiotrophin 1 Spurs Greater Regeneration Following Heart Injury Cellular Senescence as a Cause of Aging: from Wishful Thinking to Case Closed Towards Effective Sabotage of the Bacteria that Cause Tooth Decay A Perhaps Surprisingly Large Degree of Age-Related Frailty is Self-Inflicted Calorie Restriction Enhances Learning Distinctly From Effects on Health and Longevity Why and How are We Living Longer? Reprogramming Skin Cells in situ as an ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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ConclusionsFindings are discussed in the context of the broader research literature, weaknesses in the field are noted, and numerous meaningful directions for future research are presented.
Source: Journal of Adolescence - Category: Child Development Source Type: research
This study investigated the stability, survival rate, colony release and pH/sugar content of free and microencapsulated probiotic cells in orange juice. Seven types of herbal-based hydrogels (alginate-Persian Gum (PG)) were mixed with various prebiotic (fructooligosaccharides (FOS), and inulin) concentrations and then were used for microencapsulation of Lactococcus lactis ABRIINW-N19 by extrusion method. All formulations showed high encapsulation efficiency (≥98.4%) and acceptable viability of probiotic cells in simulated digestive conditions (≥61%) compared to free cells. All gel formulations showed high stability o...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
This study aimed to investigate the factors affecting the printability and post-processing capacity of cookie dough in extrusion-based 3D printing by modifying the recipe without the addition of gums or stabilizers. Cookie dough formulations with different types of fat (butter and shortening), flour (wheat, rice, and tapioca), the amount of non-fat milk (32.5 or 65 g/100 g flour), and the sugar level (37.5 or 55 g/100 g flour) were investigated for their printability and post-processing capacity. Rheological properties, microstructure, and printability of printing inks were monitored while the moisture loss and dim...
Source: Innovative Food Science and Emerging Technologies - Category: Food Science Source Type: research
This study, from the perspective of “whole food”, aimed to investigate the composition of TFE and further explore its possible health-promoting effects on cyclophosphamide-induced mice. It was found that TFE was mainly composed of carbohydrates (34.02 ± 1.42%), phenolic compounds (11.57 ± 0.14%), crude proteins (27.72 ± 3.07%) and saponins (2.81 ± 0.00%). Supplementation of TFE at 200 mg/kg·BW/d regulated intestinal homeostasis by improving the intestinal barrier, alleviating dysbacteriosis (reverse 44 of 68 disordered genera), stim...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 20 February 2020Source: Food Research InternationalAuthor(s): Zhan Ye, Chen Cao, Qiu Li, Yong-jiang Xu, Yuanfa LiuAbstractPalm oil (PO), leaf lard oil (LO), rapeseed oil (RO), sunflower oil (SO), and linseed oil (LINO) are the five of the most typical dietary lipids, while few studies have explored and compared their influences on the serum lipid profiles, colonic short chain fatty acids (SCFAs) composition and colon health of Sprague Dawley (SD) rats. Results from the present work showed that PO and LO groups showed significantly higher serum TG and TC level compared with Ctrl group, whe...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 18 February 2020Source: Food HydrocolloidsAuthor(s): Xiaqing Wu, Guowen Zhang, Mingming Hu, Junhui Pan, Ang Li, Ying ZhangAbstractAs one of the most reactive dicarbonyl compounds, methylglyoxal (MGO) can react with protein to form advanced glycation end products (AGEs), then promoting the development of diabetic complications. Hence, it is significant for preventing protein glycation mediated by MGO. Here, the anti-glycation potential and mechanism of gallocatechin gallate (GCG) as an active ingredient of green tea were investigated. It was found that GCG exhibit good scavenging activitie...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
In conclusion, unlike traditional alheiras which often contain pathogenic agents, no harmful organisms nor chemical hazards were found in these new products, even though produced by the same companies.
Source: Food Control - Category: Food Science Source Type: research
Conclusions: The study results emphasize the relevance of attachment orientation to caregiving relations in health-related contexts and call for awareness of the effect that level of depression combined with attachment orientation can have during hospitalization.Clinical implications: Assessing attachment orientation and depression in hospitalized elders might be useful for identifying older adults at risk for insufficient informal support during hospitalization. PMID: 32066347 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
Conclusion: Decidual vasculopathy at term contains the same CD56 positive extravillous endovascular trophoblasts seen with spiral artery remodeling in early pregnancy. CD56 may serve as a possible marker for decidual vasculopathy in the later stages of pregnancy. PMID: 32068473 [PubMed - as supplied by publisher]
Source: Fetal and Pediatric Pathology - Category: Pathology Tags: Fetal Pediatr Pathol Source Type: research
This study aimed to evaluate the effects on lamb meat quality of replacing the soybean meal and corn diet with peanut meal and crude glycerin. A total of 40 lambs, with an initial body weight of 17.15 ± 1.56 kg, were divided into four biodiesel by-product treatment groups: a no-treatment control, peanut meal, crude glycerin, and peanut meal + crude glycerin. The roughage-to-concentrate ratio was 40:60 in all diets. Peanut meal, crude glycerin, and their combination had no effect on the physicochemical characteristics of the meat, except the fatty acid profile. The meat from animals...
Source: Small Ruminant Research - Category: Zoology Source Type: research
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