Self-collected SARS-CoV-2 Nasal Swabs in Children and Adolescents, HIV Infection and Cardiovascular Pathology, USPSTF Recommendation on Screening for Prediabetes and Type 2 Diabetes in Children, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the September 13, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - September 13, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 934: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and environmental factors, antibody persistence and safety through 6 months after heterologous orally aerosolized Ad5-nCoV in individuals...
Source: This Week in Virology - MP3 Edition - September 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 933: Island-hopping bats
TWiV discusses a new henipavirus from fruit bats in Madagascar, and attenuation of SARS-CoV-2 Omicron disease in mice caused by genome mutations outside of the spike protein coding region. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Beijerinck virology prize (KNAW) Nipah virus vaccine (TWiV 618) Novel henipavirus from Madagascar (J Viral) Spike-independent Omicron attenuation in mice (Cell Rep) Letters read on TWiV 933 Timestamps...
Source: This Week in Virology - MP3 Edition - September 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 932: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses vaccine effectiveness against influenza illness in children, clinical manifestations of infection with poliovirus, spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice, concordance of SARS-CoV-2 results in self-collected nasal swabs vs swabs collected by health care workers in children and adolescents, probable animal-to-human transmission of SARS-CoV-2 causing a pet shop-related outbreak, laboratory-confirmed COVID-19–associated hospitalizations among adults during BA.2 variant, SARS-CoV-2 specific T-cells and antibodies, Nirmatr...
Source: This Week in Virology - MP3 Edition - September 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 930: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses antibody response against nonpoliovirus enteroviruses, clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain, object and surface contamination with monkeypox virus, monkeypox virus infection in humans across 16 countries, clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection, compassionate use of Tecovirimat for the treatment of monkeypox infection, monitoring of Pfizer-BioNTech vaccine among children, Pfizer and BioNTech announce updated vaccine data supporting efficacy in children, d...
Source: This Week in Virology - MP3 Edition - August 27, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 929: Empathyology with Andy Slavitt
Andy Slavitt joins TWiV to discuss his book, Preventable and how failures in leadership, politics, and selfishness doomed the U.S. response to SARS-CoV-2. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Guest: Andy Slavitt Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode In the Bubble podcast Preventable (Amazon) Letters read on TWiV 929 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Best big band #5: 1. Glenn Miller’s Orchestra -1940-1944: Signature song: In The Mood. Signature album: An Album Of Outstanding A...
Source: This Week in Virology - MP3 Edition - August 21, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 928: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the public health response to a polio case in a unvaccinated NY state resident, human to dog transmission of monkeypox virus, Tecovirimat and the treatment of monkeypox, detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium, what to do if you are exposed to SARS-CoV-2 and isolation and precautions for people with COVID-19, risk of SARS-CoV-2 infection in health care workers, effectiveness of HEPA filters at removing infectious SARS-CoV-2 from the air, Pfizer reports additional data on Paxlovid, hospitalization encou...
Source: This Week in Virology - MP3 Edition - August 20, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 925: First kisses and second doses
TWiV discusses monkeypox virus, poliovirus in NY, Marburg virus in Ghana, ancient herpes simplex virus type 1 genomes, and immunogenicity of different combinations of SARS-CoV-2 vaccines. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode How monkeypox virus spreads (CDC) Vaccination against monkeypox virus (CDC) Monkeypox case trends (CDC) Polio in New York State (NY Dept of Health) Poliovirus in NY wastewater (NBC New York) Marburg disease in Ghana (WHO) Ancient herpesvi...
Source: This Week in Virology - MP3 Edition - August 7, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Long COVID: The US Federal Response
On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022. Related Content: Addressing the Long-term Effects of COVID-19 Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalizat...
Source: JAMA Author Interviews - August 3, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 922: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses monkeypox infection in humans across 16 countries, pregnancy outcomes after SARS-CoV-2 infection by trimester, vaccination intent and belief, antiviral drug treatment for non-severe disease, the association of smoking with infected hospitalized patients, the association of Paxlovid on negative conversion rates among high-risk patients with COVID-19, safety and efficacy of Molnupiravir, usage of enoxaparin for primary thromboprophylaxis, statin and aspirin as therapy in infected patients, post-COVID-19 conditions among children 90 days after SARS-CoV-2 Infection, and sympt...
Source: This Week in Virology - MP3 Edition - July 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 920: Science will break your heart
From ASV 2022 in Madison, Wisconsin, TWiV speaks with Pamela Bjorkman and Andy Mehle about their careers and their research on influenza virus, HIV-1, SARS-CoV-2, and influenza virus. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guests: Pamela Bjorkman and Andy Mehle Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bjorkman laboratory Mehle laboratory Finding the groove (Nat Immunol) Structure of HLA-A2 (Nat Immunol) Mosaic RBD nanoparticles (Science) Influenza virus PB2 627 (J Virol) ANP32B or not to be (eLife) Influenza vir...
Source: This Week in Virology - MP3 Edition - July 24, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: detecting COVID variants in sewage
Since early in the pandemic, scientists have searched for signals of SARS-CoV-2 transmission by sampling wastewater. This surveillance method has provided vital information to inform public health responses. But the approach has never been particularly specific - pointing to broad trends rather than granular information such as which variants are spreading where. But now a team from the University of California have created two new tools to sample waste water in much greater detail - and spot variants and their relative concentrations up to two weeks faster than testing-based surveillance methods. In this episode of C...
Source: Nature Podcast - July 8, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 913: Twinkle twinkle little SARS
TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Poliovirus in UK sewage (ProMedMail and Science) Poliovirus eradication effort (Science) Long COVID after Delta and Omicron (Lancet) How common is long COVID? (Nature) Immune enhancers as ...
Source: This Week in Virology - MP3 Edition - June 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin
In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Reinfection outcomes (Research Square) CDC recommends v...
Source: This Week in Virology - MP3 Edition - June 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 907: When the cats and mice are away, the viruses play
TWiV discusses the situation with monkeypox, risk factors for SARS-CoV-2 infections of cats and dogs, and a lineage-tracing mouse model for studying papillomavirus infections. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox update (CDC) SARS-CoV-2 infection of cats and dogs (Emerg Inf Dis) Mouse papillomavirus identification (Vet Patrol) Mouse model for papillomavirus infection (eLife) Vincent interviews Harald zur Hausen (virology blog) Letters read on TWiV 907 Timestamps by Jolene. Th...
Source: This Week in Virology - MP3 Edition - June 12, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts