TWiV 768: Can nanobody stop these variants?
TWiV describes how human behavior, not increased transmissibility, led to increased spread of a SARS-CoV-2 variant throughout Europe in summer 2020, and nanobodies from camelid mice and llamas that efficiently neutralize variants of concern. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV Vaccine Town Hall Spread of SARS-CoV-2 variant in summer 2020 (Nature) Nanobodies neutralize SARS-CoV-2 variants (Nature) Letters read on TWiV 768 Timestamps by Jolene. Thanks! Weekly Picks Dickson...
Source: This Week in Virology - MP3 Edition - June 13, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 765: Potpourri of COVID-19
TWiV reviews the new nomenclature for SARS-CoV-2 variants, effectiveness of Pfizer/BioNTech vaccine against variants, modified Moderna vaccine against variants, impact of COVID-19 interventions on influenza in China and the US, and binding of RaTG13 spike protein to ACE2 of multiple species. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Updated nomenclature of SARS-CoV-2 variants (WHO) Pfizer-BioNTech vaccine effective against alpha variants (Lancet) Novavax vaccine effec...
Source: This Week in Virology - MP3 Edition - June 6, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: Uncertainty and the COVID 'lab-leak' theory
Since the beginning of the pandemic, there have been allegations that SARS-CoV-2 could have originated in a Chinese lab. A phase one WHO investigation concluded that a 'lab-leak' was "extremely unlikely" and yet, the theory has seen a resurgence in recent weeks with several scientists wading into the debate.In this episode of Coronapod, we delve into what scientists have been saying and ask how and why the 'lab-leak' hypothesis has gained so much traction. We ask if the way we communicate complex and nuanced science could be fuelling division, and what the fallout could be for international collaboration on ending the pand...
Source: Nature Podcast - June 4, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: Uncertainty and the COVID'lab-leak' theory
Since the beginning of the pandemic, there have been allegations that SARS-CoV-2 could have originated in a Chinese lab. A phase one WHO investigation concluded that a 'lab-leak' was "extremely unlikely" and yet, the theory has seen a resurgence in recent weeks with several scientists wading into the debate.In this episode of Coronapod, we delve into what scientists have been saying and ask how and why the 'lab-leak' hypothesis has gained so much traction. We ask if the way we communicate complex and nuanced science could be fuelling division, and what the fallout could be for international collaboration on ending the pand...
Source: Nature Podcast - June 4, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 762: SARS-CoV-2 origins with Robert Garry
Robert Garry joins TWiV to explain how the molecular biology of SARS-CoV-2 shows that it came from Nature and not a lab, including the receptor binding domain, the furin cleavage site, and the two lineages circulating in Wuhan wildlife markets. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Robert Garry Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode The proximal origin of SARS-CoV-2 (Nature) Two early genome lineages in Wuhan markets (virological.org) Insights from spike proteins of bat sarbecoviruses (virologic...
Source: This Week in Virology - MP3 Edition - May 30, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 762: SARS-CoV-2 origins with Robert Garry
Robert Garry joins TWiV to explain how the molecular biology of SARS-CoV-2 shows that it came from Nature and not a lab, including the receptor binding domain, the furin cleavage site, and the two lineages circulating in Wuhan wildlife markets. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Robert Garry Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode The proximal origin of SARS-CoV-2 (Nature) Two early genome lineages in Wuhan markets (virological.org) Insights from spike proteins of bat sarbecoviruses (virologic...
Source: This Week in Virology - MP3 Edition - May 30, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea K ølsen Fischer, Marion Koopmans
Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans, members of the WHO team investigating the origins of SARS-CoV-2 join TWiV to explain the work done by the committee during phase one, their conclusions, and the extent of work that remains to be done in phase two. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Peter on TWiV 615, 623 Thea on TWiV 576 Marion on TWiV 413, 548 WHO report on origins of SARS-CoV-2 Timestamps by Jolene. Than...
Source: This Week in Virology - MP3 Edition - May 27, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea K ølsen Fischer, Marion Koopmans
Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans, members of the WHO team investigating the origins of SARS-CoV-2 join TWiV to explain the work done by the committee during phase one, their conclusions, and the extent of work that remains to be done in phase two. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Peter on TWiV 615, 623 Thea on TWiV 576 Marion on TWiV 413, 548 WHO report on origins of SARS-CoV-2 Timestamps by Jolene. Thanks! Weekly...
Source: This Week in Virology - MP3 Edition - May 27, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea K ølsen Fischer, Marion Koopmans
Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans, members of the WHO team investigating the origins of SARS-CoV-2 join TWiV to explain the work done by the committee during phase one, their conclusions, and the extent of work that remains to be done in phase two. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Peter Daszak, Thea Kølsen Fischer, and Marion Koopmans Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Peter on TWiV 615, 623 Thea on TWiV 576 Marion on TWiV 413, 548 WHO report on origins of SARS-CoV-2 Timestamps by Jolene. Than...
Source: This Week in Virology - MP3 Edition - May 27, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Hypertonic Saline for TBI, Alpha-Blockers vs Stimulants for Preschool Children With ADHD, Maternal SARS-CoV-2 and Neonatal Outcomes, and more
Editor's Summary by Kristin Walter, MD, JAMA Fishbein Fellow, for the May 25, 2021 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - May 25, 2021 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 758: COVID-19 clinical update #63 with Dr. Daniel Griffin
In COVID-19 clinical update #63, Daniel Griffin reviews cases at child care facilities, estimates of mRNA vaccine effectiveness, risk of reinfection in university students, enhanced antibody generation with extended interval of mRNA vaccination, no benefit of convalescent plasma in hospitalized patients, and risk of clinical sequelae after acute infection. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 in child care facilities (MMWR) mRNA vaccine effectiveness (MMWR) Excelsior pass (NYS) Risk of SARS-CoV-2 r...
Source: This Week in Virology - MP3 Edition - May 22, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 757: Supershedders and super vaccines
TWiV reveals that 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in a college campus, and a nanoparticle vaccine that induces cross-reactive immunity against multiple pandemic and pre-emergent coronaviruses. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV vaccine town halls 2% of SARS-CoV-2 positives carry most viral RNA (PNAS) Pan-coronavirus nanoparticle vaccine (Nature) Why HIV-1 particles have few spikes (PLoS Path) Letters read on TWiV 757 Timestamps b...
Source: This Week in Virology - MP3 Edition - May 20, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts