TWiV 978: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the Omicron variant and severe disease, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe dis...
Source: This Week in Virology - MP3 Edition - January 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Talk Evidence - excess deaths, the ONS, and the healthcare crisis
In this week's episode, we're focusing on covid and the ongoing crisis in the NHS.
Helen Macdonald, Juan Franco and Joseph Ross cast their evidence seeking eyes over research into outcomes as well as the workload of doctors.
Firstly, Joe tells us about a new big data study into longer term outcomes after mild covid-19, how those ongoing symptoms relate to long covid, and how often they resolve themselves.
Juan looks back to his homeland to see what Argentina which was very early to offer children vaccinations against covid-19. He tells us how a new study design can help understand how effective different combinations of...
Source: The BMJ Podcast - January 27, 2023 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Talk Evidence - excess deaths, the ONS, and the healthcare crisis
In this week's episode, we're focusing on covid and the ongoing crisis in the NHS.
Helen Macdonald, Juan Franco and Joseph Ross cast their evidence seeking eyes over research into outcomes as well as the workload of doctors.
Firstly, Joe tells us about a new big data study into longer term outcomes after mild covid-19, how those ongoing symptoms relate to long covid, and how often they resolve themselves.
Juan looks back to his homeland to see what Argentina which was very early to offer children vaccinations against covid-19. He tells us how a new study design can help understand how effective different combinations of...
Source: The BMJ Podcast - January 27, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts
TWiV 977: Ageing is infectious
TWiV covers a study of SARS-CoV-2 persistence at multiple sites in the human body, and the role of endogenous retroviruses in ageing and senescence. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Persistence of SARS-CoV-2 (Nature) •Endogenous retroviruses and senescence (Cell) •Timestamps by Jolene. Thanks! Weekly Picks Dickson – Baritone Saxoph...
Source: This Week in Virology - MP3 Edition - January 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 976: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently inves...
Source: This Week in Virology - MP3 Edition - January 21, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 975: Crossing the Ts with Daniela Weiskopf
Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Daniela Weiskopf Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •Cross reactive T cells to SARS-CoV-2 (Science) •SARS-CoV-2 exposure history and T cell response (Cell Rep Med) •Spike T cells cross- recognize Omicron (Natur...
Source: This Week in Virology - MP3 Edition - January 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 974: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses poliovirus returns to New York wastewater, COVID-19 is more widespread in animals than we thought, increasing ventilation reduces SARS-CoV-2 airborne transmission in schools, the use of carbon dioxide monitoring to assess ventilation at a national infectious diseases conference, effectiveness of the bivalent mRNA vaccine in preventing severe COVID-19 outcomes, 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection, and long COVID outcomes at one year after mild SARS-CoV-2 infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS...
Source: This Week in Virology - MP3 Edition - January 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 972: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans, time to negative PCR conversion among high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated by Sotrovimab or Nirmatrelvir, COVID drug Paxlovid was hailed as a game-changer,...
Source: This Week in Virology - MP3 Edition - January 7, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 970: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roommate-to-roommate transmission of severe SARS-CoV-2, clinical validation of a novel T-Cell receptor sequencing assay for identification of recent or prior SARS-CoV-2 infection, antibody-dependent cellular cytotoxicity against SARS-...
Source: This Week in Virology - MP3 Edition - December 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 967: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses how immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection, prevalence of SARS-CoV-2 and influenza coinfection and clinical characteristics among children and adolescents aged (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - December 24, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 965: Asking Esper Kallas for some I.D.
Brazilian infectious diseases physician Esper Kallas returns to TWiV to discuss the state of viral diseases in his country, including those cause by Zika, dengue, and yellow fever viruses, MPOX, and SARS-CoV-2. Hosts: Vincent Racaniello and Alan Dove Guest: Esper Kallas Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) with promo code MicrobeTV International Scientific Coordinator Position (agajewski at icsnicaragua.org for more info) Viral kinetics in sylvatic yellow fever (J Inf Dis) Safety an...
Source: This Week in Virology - MP3 Edition - December 18, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 964: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster, efficacy of antiviral agents against omicron subvariants BQ.1.1 and XBB, incide...
Source: This Week in Virology - MP3 Edition - December 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 963: Feline coronavirus with Gary Whittaker
Vincent travels to Cornell University to speak with Gary Whittaker about regulation by proteolytic processing of the fusion activity of the spike protein of SARS-CoV-2, and feline coronavirus transmission, replication and disease. Hosts: Vincent Racaniello Guest: Gary Whittaker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode SARS-CoV-2 spike and its furin cleavage site (Lancet Microbe) TMPRSS2 inhibitor blocks SARS-CoV-2 reproduction (Nature) Distinct spike proteins of feline coronaviruses (Viruses) Feline coronavirus and feline infectious peritonitis (J...
Source: This Week in Virology - MP3 Edition - December 14, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 961: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals, sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody for breakthrough infections during the epidemic of the Omicron variants, effect of wearing glasses on risk...
Source: This Week in Virology - MP3 Edition - December 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 959: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preterm birth is affected by the timing of symptomatic SARS-CoV-2 infection during pregnancy, medical masks versus N95 respirators for...
Source: This Week in Virology - MP3 Edition - December 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
