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Infectious Disease: Endemics

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Total 16431 results found since Jan 2013.

Seseli bocconei Guss. and S. tortuosum subsp. maritimum Guss. essential oils inhibit colon cancer cell viability
In this study, the chemical compositions of two essential oils (EOs) obtained from different parts (flowers, leaves, stems, and roots) of Seseli bocconei Guss. and of Seseli tortuosum subsp. maritimum Guss., wild endemic species of Sicily, were investigated. The main classes of metabolites for the essential oils of S. bocconei were, respectively, monoterpenes hydrocarbons for flowers, sesquiterpenes hydrocarbons for leaves, and a breakdown between the two previously mentioned classes for stems. In the case of S. tortuosum subsp. maritimum, on the other hand, the main metabolite class for all the vegetative parts analyzed (...
Source: Fitoterapia - September 14, 2023 Category: Biochemistry Authors: Alessandro Vaglica Antonella Maggio Natale Badalamenti Maurizio Bruno Marianna Lauricella Antonella D'Anneo Source Type: research

Structure of glyceraldehyde-3-phosphate dehydrogenase from Paracoccidioides lutzii in complex with an aldonic sugar acid
Biochimie. 2023 Sep 12:S0300-9084(23)00240-7. doi: 10.1016/j.biochi.2023.09.013. Online ahead of print.ABSTRACTThe pathogen Paracoccidioides lutzii (Pb01) is found in South America countries Colombia, Ecuador, Venezuela and Brazil, especially in the central, west, and north regions of the latter. It belongs to the Ajellomycetaceae family, Onygenales order, and is typically thermodimorphic, presenting yeast cells when it grows in animal tissues, but mycelia when in the environment, where it produces the infectious propagule. Moreover, this fungus is one of the etiologic agents of Paracoccidioidomycosis (PCM), the most impor...
Source: Biochimie - September 14, 2023 Category: Biochemistry Authors: Jonathan Heiler Hern ández-Prieto Viviane Paula Martini Jorge Iulek Source Type: research

Seseli bocconei Guss. and S. tortuosum subsp. maritimum Guss. essential oils inhibit colon cancer cell viability
In this study, the chemical compositions of two essential oils (EOs) obtained from different parts (flowers, leaves, stems, and roots) of Seseli bocconei Guss. and of Seseli tortuosum subsp. maritimum Guss., wild endemic species of Sicily, were investigated. The main classes of metabolites for the essential oils of S. bocconei were, respectively, monoterpenes hydrocarbons for flowers, sesquiterpenes hydrocarbons for leaves, and a breakdown between the two previously mentioned classes for stems. In the case of S. tortuosum subsp. maritimum, on the other hand, the main metabolite class for all the vegetative parts analyzed (...
Source: Fitoterapia - September 14, 2023 Category: Biochemistry Authors: Alessandro Vaglica Antonella Maggio Natale Badalamenti Maurizio Bruno Marianna Lauricella Antonella D'Anneo Source Type: research

Congenital Mpox Syndrome (Clade I) in Stillborn Fetus after Placental Infection and Intrauterine Transmission, Democratic Republic of the Congo, 2008
We report the autopsy pathology findings of a 21-week stillborn fetus with congenital mpox syndrome that occurred in the Democratic Republic of the Congo in 2008. The fetus acquired mpox from the mother after intrauterine transplacental monkeypox virus transmission. We confirmed monkeypox virus infection in the mother, fetus, and placenta by using a monkeypox virus-specific quantitative PCR. Subtyping of the virus was not performed, but the mother and fetus were almost certainly infected with the clade I variant that was endemic in the Democratic Republic of the Congo at the time. Risk for intrauterine infection appears to...
Source: Emerging Infectious Diseases - September 13, 2023 Category: Infectious Diseases Authors: David A Schwartz Placide Mbala-Kingebeni Kerry Patterson John W Huggins Phillip R Pittman Source Type: research

Prevalence of Strongyloides in Southeast Asia: a systematic review and meta-analysis with implications for public health and sustainable control strategies
ConclusionsA high prevalence of strongyloidiasis in Southeast Asia was revealed, highlighting the importance of the region ’s ongoing research, surveillance, and control efforts. Factors contributing to the strongyloidiasis transmission include the role of animal hosts, the impact of global connectivity, and the significance of the co-endemicity of otherStrongyloides species. Based on these findings, a multi-pronged One-Health approach is essential for sustainable intervention and control.
Source: Infectious Diseases of Poverty - September 13, 2023 Category: Infectious Diseases Source Type: research

microRNA silencing in a whole worm cestode model provides insight into miR-71 function
This study provides new knowledge on gene expression regulation in cestodes and suggests that miRNAs could be evaluated as new selective therapeutic targets for treating Neglected Tropical Diseases prioritised by the World Health Organization.PMID:37699506 | DOI:10.1016/j.ijpara.2023.08.002
Source: International Journal for Parasitology - September 12, 2023 Category: Parasitology Authors: Andr és Grecco Natalia Macchiaroli Mat ías Pérez Adriano Casulli Marcela Cucher Mara Cecilia Rosenzvit Source Type: research

Effects of fluoride on oxidative DNA damage, nitric oxide level, lipid peroxidation and cholinesterase enzyme activity in a rotenone-induced experimental Parkinson's model
CONCLUSIONS: Findings suggest that NaF and ROT may interact synergistically leading to oxidative damage and neuronal cell loss. As a result, we believe that exposure to pesticides in combination with NaF is one of the environmental factors that should not be ignored in the etiology of neurological diseases such as PD in populations in areas with endemic fluorosis.PMID:37699078 | DOI:10.1080/01616412.2023.2257452
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Yilmaz Kocak Gokhan Oto Zubeyir Huyut Hamit Hakan Alp Fikret Turkan Ezgi Onay Source Type: research

Evaluation of the Potential Therapeutic Properties of Liquidambar orientalis Oil
In conclusion, the oil from the Sigla tree offers promising therapeutic potential and warrants further exploration.PMID:37699128 | DOI:10.1002/cbdv.202300291
Source: Chemistry and Biodiversity - September 12, 2023 Category: Biochemistry Authors: Mehmet Cengiz Baloglu Lutfiye Yildiz Ozer Buket Pirci Gokhan Zengin Abdullahi Ibrahim Uba Yasemin Celik Altunoglu Source Type: research

microRNA silencing in a whole worm cestode model provides insight into miR-71 function
This study provides new knowledge on gene expression regulation in cestodes and suggests that miRNAs could be evaluated as new selective therapeutic targets for treating Neglected Tropical Diseases prioritised by the World Health Organization.PMID:37699506 | DOI:10.1016/j.ijpara.2023.08.002
Source: International Journal for Parasitology - September 12, 2023 Category: Parasitology Authors: Andr és Grecco Natalia Macchiaroli Mat ías Pérez Adriano Casulli Marcela Cucher Mara Cecilia Rosenzvit Source Type: research