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Infectious Disease: Endemics

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Total 16431 results found since Jan 2013.

Preferences of Patients and Providers in High-Burden Malaria Settings for Long-Acting Malaria Chemoprevention
Am J Trop Med Hyg. 2023 Aug 21:tpmd230245. doi: 10.4269/ajtmh.23-0245. Online ahead of print.ABSTRACTAntimalarial medications are recommended for chemoprevention as part of malaria control programs to decrease the morbidity and mortality related to more than 200 million infections each year. We sought to evaluate patient and provider acceptability of malaria chemoprevention in a long-acting formulation. We administered questionnaires to patients and providers in malaria endemic districts in Kenya and Zambia. Questions explored preferences and concerns around long-acting antimalarial formulations compared with oral formulat...
Source: Am J Trop Med Hyg - August 21, 2023 Category: Infectious Diseases Authors: Kimberly K Scarsi Harlan Sayles Kelvin Kapungu Peter Sifuna Matthew M Ippolito Renae Furl Matthew J Anderson Joelle Dountio Ofimboudem Gershom Chongwe Jack Hutter Steven P Rannard Andrew Owen Susan Swindells Source Type: research

Clinical Presentation of American Tegumentary Leishmaniasis in a Leishmania (Viannia) braziliensis Endemic Hotspot: A 35-Year History
Am J Trop Med Hyg. 2023 Aug 21:tpmd230234. doi: 10.4269/ajtmh.23-0234. Online ahead of print.ABSTRACTAmerican tegumentary leishmaniasis (ATL) is a neglected tropical disease affecting the skin and mucosa. American tegumentary leishmaniasis due to Leishmania (Viannia) braziliensis is endemic in Argentina, where the Department of Oran is a hyperendemic focus. All cases of ATL with laboratory confirmation evaluated at a referral center in Oran city between 1985 and 2019 were analyzed retrospectively. Information from cases included clinical form, lesion size and number, time of evolution, and anatomical location; sex, age, an...
Source: Am J Trop Med Hyg - August 21, 2023 Category: Infectious Diseases Authors: Mar ía Cristina Almazán Silvana Pamela Cajal Melisa D íaz-Fernández Marisa Ju árez Marcelo Quipildor Guillermo Portal Valeria Tejerina Carlos Vargas Griselda Noem í Copa Jos é Fernando Gil Rub én Oscar Cimino Alejandro Javier Krolewiecki Source Type: research

Preferences of Patients and Providers in High-Burden Malaria Settings for Long-Acting Malaria Chemoprevention
Am J Trop Med Hyg. 2023 Aug 21:tpmd230245. doi: 10.4269/ajtmh.23-0245. Online ahead of print.ABSTRACTAntimalarial medications are recommended for chemoprevention as part of malaria control programs to decrease the morbidity and mortality related to more than 200 million infections each year. We sought to evaluate patient and provider acceptability of malaria chemoprevention in a long-acting formulation. We administered questionnaires to patients and providers in malaria endemic districts in Kenya and Zambia. Questions explored preferences and concerns around long-acting antimalarial formulations compared with oral formulat...
Source: The American Journal of Tropical Medicine and Hygiene - August 21, 2023 Category: Tropical Medicine Authors: Kimberly K Scarsi Harlan Sayles Kelvin Kapungu Peter Sifuna Matthew M Ippolito Renae Furl Matthew J Anderson Joelle Dountio Ofimboudem Gershom Chongwe Jack Hutter Steven P Rannard Andrew Owen Susan Swindells Source Type: research

Clinical Presentation of American Tegumentary Leishmaniasis in a Leishmania (Viannia) braziliensis Endemic Hotspot: A 35-Year History
Am J Trop Med Hyg. 2023 Aug 21:tpmd230234. doi: 10.4269/ajtmh.23-0234. Online ahead of print.ABSTRACTAmerican tegumentary leishmaniasis (ATL) is a neglected tropical disease affecting the skin and mucosa. American tegumentary leishmaniasis due to Leishmania (Viannia) braziliensis is endemic in Argentina, where the Department of Oran is a hyperendemic focus. All cases of ATL with laboratory confirmation evaluated at a referral center in Oran city between 1985 and 2019 were analyzed retrospectively. Information from cases included clinical form, lesion size and number, time of evolution, and anatomical location; sex, age, an...
Source: The American Journal of Tropical Medicine and Hygiene - August 21, 2023 Category: Tropical Medicine Authors: Mar ía Cristina Almazán Silvana Pamela Cajal Melisa D íaz-Fernández Marisa Ju árez Marcelo Quipildor Guillermo Portal Valeria Tejerina Carlos Vargas Griselda Noem í Copa Jos é Fernando Gil Rub én Oscar Cimino Alejandro Javier Krolewiecki Source Type: research

Screening of the phytochemical constituents of Teucrium polium extract and evaluation of their prophylactic role against the oxidative damage and cytotoxicity of Aflatoxin B < sub > 1 < /sub > in rats
This study aimed to determine the bioactive components of Teucrium polium methanolic extract (TPE) and to evaluate their protective role against AFB1-induced oxidative damage, cytotoxicity, and genotoxicity in rats. Six groups of male albino rats were treated orally for 4 weeks including the control group, the ِAFB1-treated group (80 μg/kg b.w.), the groups treated with low (LD) or high (HD) dose TPE (50 or 100 mg/kg b.w.), and the groups treated with AFB1 plus TEP (LD) or TPE (HD). Blood and serum samples were collected for different assays. The GC-MS identified 34 compounds, the major compounds were pinene, germacrene ...
Source: Toxicon - August 19, 2023 Category: Toxicology Authors: Zineddine Boutefaha Kawthar A Diab Sara Gheraibia Aziza A El-Nekeety Noureddine Belattar Marwa E Hassan Sekena H Abdel-Aziem Nabila S Hassan Mosaad A Abdel-Wahhab Source Type: research

Clinical features and diagnostic challenges of mpox (monkeypox) outbreak in Malta: a retrospective cohort study
CONCLUSION: The results shed light on unique challenges faced by the local sexual health clinic and call for more resources in response to the global emerging of infectious diseases.PMID:37592818 | DOI:10.1111/ijd.16811
Source: Herpes - August 18, 2023 Category: Infectious Diseases Authors: Matthew Valentino Katya Muscat Alexandra Gauci Donia Gamoudi Valeska Padovese Source Type: research

Phytochemical profiling by UPLC-ESI-QTOF-MS of Kalaharia uncinata (Schinz) Moldenke, widely used in traditional medicine in DR Congo
This study aimed to perform a phytochemical characterization of K. uncinata and to discuss the potential bioactivity of the identified phytochemical constituents based on documented data. Ultra-performance liquid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOF-MS) was used for profiling and identification of the main phytochemical constituents from leaf extracts (MeOH 90%, dichloromethane, EtOAc, n-BuOH, n-hexane and residue) of K.uncinata. Twenty-four constituents, representing mainly flavonoids (14), followed by phenylethanoid glycosides (7), phenolic acids (2), and ...
Source: Chemistry and Biodiversity - August 18, 2023 Category: Biochemistry Authors: Pathy Kibungu Kembelo Emmy Tuenter Tuenter Wouter Vanhove Honor é Belesi Katula Patrick Van Damme Luc Pieters Source Type: research

Retrospective analysis of clinico-laboratory parameters, outcome and predictors of scrub typhus co- infection in covid-19 affected children
The objective of this study was to describe clinico-laboratory parameters, outcome and predictors of scrub typhus co- infection in COVID-19 affected children. Ours was a retrospective analysis done in a tertiary care pediatric COVID facility. COVID-19 positive children in the age group of 1 month to 12 years who were tested for scrub typhus co-infection between May to August 2020 were included in the study. In all positive cases, clinical, laboratory, treatment and outcome data were analyzed. Relevant data were compared between scrub typhus confirmed, and suspected but negative patients. All six patients with co-infection ...
Source: Tropical Doctor - August 17, 2023 Category: Tropical Medicine Authors: Mihir Sarkar Aniket Roy Subhajit Bhakta Satyabrata Roy Chowdhoury Rakesh Kumar Mandal Source Type: research