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Infectious Disease: Endemics
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Analysis of google trends and search results for ophthalmic symptoms of monkeypox
ConclusionSearch interest in monkeypox ophthalmic symptoms corresponds with geographic and temporal trends, i.e., timing and location of the first reported non-endemic cases and WHO announcement. Although ophthalmic symptoms are not as widely searched currently, inclusion in public health messaging is key for diagnosis, appropriate management, and reduction of further transmission.
Source: International Ophthalmology - April 18, 2023 Category: Opthalmology Source Type: research
Real-time estimation of disease activity in emerging outbreaks using internet search information
by Emily L. Aiken, Sarah F. McGough, Maimuna S. Majumder, Gal Wachtel, Andre T. Nguyen, Cecile Viboud, Mauricio Santillana
Understanding the behavior of emerging disease outbreaks in, or ahead of, real-time could help healthcare officials better design interventions to mitigate impacts on affected populations. Most healthcare-based disease surveillance systems, however, have significant inherent reporting delays due t o data collection, aggregation, and distribution processes. Recent work has shown that machine learning methods leveraging a combination of traditionally collected epidemiological information and novel Inter...
Source: PLoS Computational Biology - August 16, 2020 Category: Biology Authors: Emily L. Aiken Source Type: research
Parasitological and molecular search for leishmania natural infection in phlebotomine sand flies in peri-urban sites of an argentinean area endemic for tegumentary leishmaniasis
Acta Trop. 2021 Jul 21:106064. doi: 10.1016/j.actatropica.2021.106064. Online ahead of print.ABSTRACTLeishmaniases are neglected tropical diseases caused by Leishmania spp. parasites transmitted by the bite of phlebotomine sand flies. In Argentina, the most endemic area of American Tegumentary leishmaniasis (ATL) has been Orán department, Province of Salta, where Leishmania (Viannia) braziliensis prevails and Nyssomyia neivai is considered as its vector, although there is no accurate and sufficient information in this regard. The aim of this work was to search for natural infection by Leishmania spp. in sand flies from pe...
Source: Acta Tropica - July 24, 2021 Category: Infectious Diseases Authors: Mar ía Cristina Almazán Griselda Noem í Copa Jos é Fernando Gil In és López Quiroga Melisa Evangelina D íaz Fernández Alejandro Uncos Carlos Lorenzo Hoyos Julio Rub én Nasser Paola Andrea Barroso Jorge Diego Marco Source Type: research
Parasitological and molecular search for leishmania natural infection in phlebotomine sand flies in peri-urban sites of an argentinean area endemic for tegumentary leishmaniasis
Acta Trop. 2021 Jul 21:106064. doi: 10.1016/j.actatropica.2021.106064. Online ahead of print.ABSTRACTLeishmaniases are neglected tropical diseases caused by Leishmania spp. parasites transmitted by the bite of phlebotomine sand flies. In Argentina, the most endemic area of American Tegumentary leishmaniasis (ATL) has been Orán department, Province of Salta, where Leishmania (Viannia) braziliensis prevails and Nyssomyia neivai is considered as its vector, although there is no accurate and sufficient information in this regard. The aim of this work was to search for natural infection by Leishmania spp. in sand flies from pe...
Source: Acta Tropica - July 24, 2021 Category: Infectious Diseases Authors: Mar ía Cristina Almazán Griselda Noem í Copa Jos é Fernando Gil In és López Quiroga Melisa Evangelina D íaz Fernández Alejandro Uncos Carlos Lorenzo Hoyos Julio Rub én Nasser Paola Andrea Barroso Jorge Diego Marco Source Type: research
“Chagas Express XXI”: A new ArtScience social technology for health and science education—A case study in Brazilian endemic areas of Chagas disease with an active search of chronic cases
ConclusionsCE21 is a social technology potentially useful for health and science education and active search of asymptomatic CD chronic cases. Moreover, this technology may be adapted to understand and to cooperate in other potentially epidemic situations, especially NTDs related.
Source: PLoS Neglected Tropical Diseases - July 21, 2021 Category: Tropical Medicine Authors: Tania C. Araujo-Jorge Source Type: research
Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology
Malaria is an endemic disease that affected 229 million people and caused 409 thousand deaths, in 2019. Disease control is based on early diagnosis and specific treatment with antimalarial drugs since no effective vaccines are commercially available to prevent the disease. Drug chemotherapy has a strong historical link to the use of traditional plant infusions and other natural products in various cultures. The research based on such knowledge has yielded two drugs in medicine: the alkaloid quinine from Cinchona species, native in the Amazon highland rain forest in South America, and artemisinin from Artemisia annua, a spe...
Source: Frontiers in Pharmacology - September 22, 2021 Category: Drugs & Pharmacology Source Type: research
In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia.
Abstract
Chagas disease remains a major impediment to sustainable socioeconomic development in Latin America. Transplacental transmission explains the persistence of transmission in urban areas, in non-endemic regions, and in areas with an established interrupted vectorial transmission. One of every five cases of congenital Chagas disease in the world occurs in Colombia and Venezuela. The massive migration of impoverished populations from neighboring Venezuela has worsened the situation creating a humanitarian crisis in Northeastern Colombia, including the Sierra Nevada de Santa Marta. The prevalence of Chagas inf...
Source: The American Journal of Tropical Medicine and Hygiene - June 30, 2019 Category: Tropical Medicine Authors: Parra-Henao G, Oliveros H, Hotez PJ, Motoa G, Franco-Paredes C, Henao-Martínez AF Tags: Am J Trop Med Hyg Source Type: research
Anthropophilic phlebotomine sand fly Lutzomyia species and search for the natural Leishmania infections in an area endemic for cutaneous leishmaniasis in Ecuador.
Abstract
By employing protected human bait landing and modified Shannon light trap, a total of 1,924 phlebotomine sand fly Lutzomyia spp. were captured in an area from which L. (V.) guyanensis was reported as the causative parasite of cutaneous leishmaniasis (CL). The sand flies captured alive were dissected and identified at species level, based mainly on their spermathecae. At the same time, the sand flies dissected were searched for the Leishmania parasites by microscopic-test, and later on by PCR-test. No positive sand flies were detected by both tests, while considerable numbers of anthropophilic sand fly spe...
Source: Acta Tropica - November 28, 2019 Category: Infectious Diseases Authors: Hashiguchi Y, Gomez EA, Velez LN, Villegas NV, Kubo M, Mimori T, Hashiguchi K, Kato H Tags: Acta Trop Source Type: research
Plague vaccines: new developments in an ongoing search
Appl Microbiol Biotechnol. 2021 Jun 18. doi: 10.1007/s00253-021-11389-6. Online ahead of print.ABSTRACTAs the reality of pandemic threats challenges humanity, exemplified during the ongoing SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of disease has become increasingly critical. Of paramount concern are novel and reemerging pathogens that could trigger such events, including the plague bacterium Yersinia pestis. Y. pestis is responsible for more human deaths than any other known pathogen and exists globally in endemic regions of the world, including the four corners region and North...
Source: Applied Microbiology and Biotechnology - June 18, 2021 Category: Microbiology Authors: Jason A Rosenzweig Emily K Hendrix Ashok K Chopra Source Type: research
Innovative tracking, active search and follow-up strategies for new leprosy cases in the female prison population
by Claudia Maria Lincoln Silva, Fred Bernardes Filho, Glauber Voltan, Jaci Maria Santana, Marcel Nani Leite, Filipe Rocha Lima, Luisiane de Avila Santana, Nat ália Aparecida de Paula, Patricia Toscano Barreto Nogueira Onofre, Wilson Marques-Junior, Vanessa Aparecida Tomaz, Carmem Sílvia Vilela Pinese, Marco Andrey Cipriani Frade
BackgroundRegarding the leprosy transmission through the upper airways, overcrowded locations such as prisons can become a risk to get sick. Like the leprosy hidden endemic demonstrated in male prison population, being interesting to assess the leprosy scene also among confined women. MethodsA pr...
Source: PLoS Neglected Tropical Diseases - August 20, 2021 Category: Tropical Medicine Authors: Claudia Maria Lincoln Silva Source Type: research
Why are tapeworm carriers so difficult to find? A methodological proposal for their search and recovery
This study is aimed to find and evaluate T. solium carriers, describing some characteristics of these patients and the treatment. Taeniasis cases were searched for in various Mexican states from 1983 to 2016. Previous informed consent, tapeworm-carrier patients were administered with niclosamide and a saline purge. Parasite specimens were recovered and identified, both morphologically and by PCR. From 117 treated patients, Taenia sp. specimens were obtained from 46 subjects (47.8%). From these, complete parasites were recovered from 42 (90.5%), and only detached proglottids from 4 patients. Cases were more frequent in More...
Source: Experimental Parasitology - April 4, 2023 Category: Parasitology Authors: N Villalobos Martinez M J G Nu ñez M A Figueroa D A Flisser E Sciutto Source Type: research
