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Both moderate- and high-intensity exercise training increase intramyocellular lipid droplet abundance and modify myocellular distribution in adults with obesity
This study compared high-intensity interval training (HIIT) with more conventional moderate-intensity continuous training (MICT) on intramyocellular lipid content, as well as LD characteristics (size and number) and abundance within the intramyofibrillar (IMF) and subsarcolemmal (SS) regions of type I and type II skeletal muscle fibers in adults with obesity. Thirty-six adults with obesity (BMI=33±3 kg/m2) completed 12 weeks (4d/week) of either HIIT (10x1 min, 90% HRmax + 1 min active recovery; n=19) or MICT (45 min steady-state exercise, 70% HRmax; n=17), while on a weight-maintaining diet throughout training. Skeletal m...
Source: American Journal of Physiology. Endocrinology and Metabolism - September 20, 2023 Category: Physiology Authors: Michael W Schleh Cheehoon Ahn Benjamin J Ryan Olivia K Chugh Austin T Luker Kathryn E Luker Jenna B Gillen Alison C Ludzki Douglas W Van Pelt Lisa M Pitchford Tao Zhang Thomas Rode Suzette M Howton Charles F Burant Jeffrey F Horowitz Source Type: research
NLM Technical Bulletin, Sep-Oct 2023, Upcoming Live Training: Standardize Your Research Data with the NIH Common Data Element Repository
Through live demonstrations and hands-on exercises, this course will introduce you to common data elements (CDEs) and the NIH Common Data Element Repository (CDE-R). The course begins with an in-depth introduction to what CDEs are and examples of how researchers are already using them. Then, you 19ll see how to search the repository and practice searching on your own. Subject matter experts will be in attendance to answer your questions.
Source: NLM Technical Bulletin - September 19, 2023 Category: Databases & Libraries Source Type: news
The effects of low-intensity resistance training with blood flow restriction versus traditional resistance exercise on lower extremity muscle strength and motor functionin ischemic stroke survivors: a randomized controlled trial
CONCLUSION: LIRT-BFR produced a significant improvement in muscle strength, balance, walking capacity, and anxiety and depression in ischemic stroke patients, and the improvement are comparable to HIRT.CLINICAL TRIAL REGISTRATION: NCT05281679.PMID:37724785 | DOI:10.1080/10749357.2023.2259170
Source: Topics in Stroke Rehabilitation - September 19, 2023 Category: Neurology Authors: Ishtiaq Ahmed Rustem Mustafoglu Belgin Erhan Source Type: research
Effect of functional resistance training on the structure and function of the heart and liver in patients with non-alcoholic fatty liver
Sci Rep. 2023 Sep 19;13(1):15475. doi: 10.1038/s41598-023-42687-w.ABSTRACTThe current study is of the quasi-experimental type, with a pre-and post-test design, and subjects were randomly assigned to one of two groups: control (n = 8) and experimental (test) (n = 8). Based on the patient's self-report and using daily diet control tables, the patient's diet planning percentage of energy supply was managed and controlled for 3 days. The protocol for functional resistance training for these circular exercises, including the squat, lunge, bear crawl, rock press, jumping jack, and back fly lunge, was performed three times per we...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Ramin Jafarikhah Arsalan Damirchi Farhad Rahmani Nia Seyyed Mohammad Taghi Razavi-Toosi Afshin Shafaghi Mostafa Asadian Source Type: research
Working Memory Training for Children Using the Adaptive, Self-Select, and Stepwise Approaches to Setting the Difficulty Level of Training Activities: Protocol for a Randomized Controlled Trial
CONCLUSIONS: This trial will determine whether the adaptive approach to setting the difficulty of training activities maximizes cognitive training outcomes for children. This trial has several strengths: it adopts best practices for cognitive training studies (design, methods, and analysis plan); uses a range of measures to detect discrete levels of transfer; has a 6-month postintervention assessment; is appropriately powered; and uses an experimental working memory training intervention based on our current understanding of the cognitive mechanisms of training. Findings will inform future research and design of cognitive ...
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Regine Cassandra Lau Peter John Anderson Joshua F Wiley Derek Huang Faisha Surjatin Paul McIntosh Susan Gathercole Megan Spencer-Smith Source Type: research
Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-associated Immunity in Lynch Syndrome
CONCLUSIONS: Together these data have important implications for cancer interception in LS, and document for the first-time biological effects of exercise in the immune system of a target organ in patients at-risk for cancer.PMID:37724990 | DOI:10.1158/1078-0432.CCR-23-0088
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Nan Deng Laura Reyes-Uribe Johannes F Fahrmann Whittney S Thoman Mark F Munsell Jennifer B Dennison Eunice Murage Ranran Wu Ernest T Hawk Selvi Thirumurthi Patrick M Lynch Christina M Dieli-Conwright Alexander J Lazar Sonali Jindal Khoi Chu Manoj Chelvana Source Type: research
Development and validation of the CAIL prognostic score in non-small cell lung cancer patients with malignant pleural effusion
CONCLUSIONS: For NSCLC patients with MPE, the validated CAIL prognostic score integrates clinical characteristics and therapeutic modalities to predict survival.PMID:37723659 | DOI:10.1111/crj.13700
Source: Clinical Lung Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Tianyuan Li Panwen Tian Qin Huang Hao Zeng Qi Wei Yalun Li Source Type: research
Women's experiences of primary dysmenorrhea symptoms: a systematic review of qualitative evidence and meta-aggregation
Women Health. 2023 Sep 14;63(8):658-668. doi: 10.1080/03630242.2023.2255289. Epub 2023 Sep 19.ABSTRACTPrimary dysmenorrhea (PD) has a significant impact on women's lives, especially among young women who miss school and work due to painful periods. Experiences and how women manage PD have been explored to some extent, but the evidence has not been systematically collated and reviewed to allow health professionals to better understand women's experiences of and perceptions about PD. Hence, we aim to synthesize the qualitative evidence related to women's experiences of PD and associated symptoms. For this purpose, seven data...
Source: Women and Health - September 19, 2023 Category: Primary Care Authors: Ana Moreno G ómez Ping Guo Ana Isabel de la Llave Rinc ón Nikolaos Efstathiou Source Type: research
Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-associated Immunity in Lynch Syndrome
CONCLUSIONS: Together these data have important implications for cancer interception in LS, and document for the first-time biological effects of exercise in the immune system of a target organ in patients at-risk for cancer.PMID:37724990 | DOI:10.1158/1078-0432.CCR-23-0088
Source: Clinical Colorectal Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Nan Deng Laura Reyes-Uribe Johannes F Fahrmann Whittney S Thoman Mark F Munsell Jennifer B Dennison Eunice Murage Ranran Wu Ernest T Hawk Selvi Thirumurthi Patrick M Lynch Christina M Dieli-Conwright Alexander J Lazar Sonali Jindal Khoi Chu Manoj Chelvana Source Type: research
Aortic Annulus Detection Based on Deep Learning for Transcatheter Aortic Valve Replacement Using Cardiac Computed Tomography
CONCLUSION: Our deep learning framework was feasible to detect the 3D complex structure of the aortic annulus plane using cardiac CT for TAVR. The performance of our algorithms was higher than other convolutional neural networks.PMID:37724499 | DOI:10.3346/jkms.2023.38.e306
Source: J Korean Med Sci - September 19, 2023 Category: General Medicine Authors: Yongwon Cho Soojung Park Sung Ho Hwang Minseok Ko Do-Sun Lim Cheol Woong Yu Seong-Mi Park Mi-Na Kim Yu-Whan Oh Guang Yang Source Type: research
Learning Language, Un/Learning Empathy in Medical School
This article considers the ways in which empathy for patients and related solidarity with communities may be trained out of medical students during medical school. The article focuses especially on the pre-clinical years of medical school, those that begin with orientation and initiation events such as the White Coat Ceremony. The ethnographic data for the article come from field notes and recordings from my own medical training as well as hundreds of hours of observant participation and interviews with medical students over the past several years. Exploring the framework of language socialization, I argue that learning th...
Source: Culture, Medicine and Psychiatry - September 19, 2023 Category: Psychiatry Authors: Seth M Holmes Source Type: research
Nomogram based on clinical characteristics and radiological features for the preoperative prediction of spread through air spaces in patients with clinical stage IA non-small cell lung cancer: a multicenter study
CONCLUSION: The nomogram created in this study, based on clinical characteristics and radiological features, has a high diagnostic efficiency for predicting the STAS status in patients with clinical stage IA NSCLC and may support the creation of personalized treatment strategies before surgery.PMID:37724737 | DOI:10.4274/dir.2023.232404
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 19, 2023 Category: Radiology Authors: Yun Wang Deng Lyu Di Zhang Lei Hu Junhong Wu Wenting Tu Yi Xiao Li Fan Shiyuan Liu Source Type: research
Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-associated Immunity in Lynch Syndrome
CONCLUSIONS: Together these data have important implications for cancer interception in LS, and document for the first-time biological effects of exercise in the immune system of a target organ in patients at-risk for cancer.PMID:37724990 | DOI:10.1158/1078-0432.CCR-23-0088
Source: Clinical Cancer Research - September 19, 2023 Category: Cancer & Oncology Authors: Nan Deng Laura Reyes-Uribe Johannes F Fahrmann Whittney S Thoman Mark F Munsell Jennifer B Dennison Eunice Murage Ranran Wu Ernest T Hawk Selvi Thirumurthi Patrick M Lynch Christina M Dieli-Conwright Alexander J Lazar Sonali Jindal Khoi Chu Manoj Chelvana Source Type: research
Overcoming the Challenges in the Development and Implementation of Artificial Intelligence in Radiology: A Comprehensive Review of Solutions Beyond Supervised Learning
Korean J Radiol. 2023 Aug 28. doi: 10.3348/kjr.2023.0393. Online ahead of print.ABSTRACTArtificial intelligence (AI) in radiology is a rapidly developing field with several prospective clinical studies demonstrating its benefits in clinical practice. In 2022, the Korean Society of Radiology held a forum to discuss the challenges and drawbacks in AI development and implementation. Various barriers hinder the successful application and widespread adoption of AI in radiology, such as limited annotated data, data privacy and security, data heterogeneity, imbalanced data, model interpretability, overfitting, and integration wit...
Source: Korean J Radiol - September 19, 2023 Category: Radiology Authors: Gil-Sun Hong Miso Jang Sunggu Kyung Kyungjin Cho Jiheon Jeong Grace Yoojin Lee Keewon Shin Ki Duk Kim Seung Min Ryu Joon Beom Seo Sang Min Lee Namkug Kim Source Type: research
Role of registered dietitians in nasoenteric feeding tube placement
Nutr Clin Pract. 2023 Sep 19. doi: 10.1002/ncp.11071. Online ahead of print.ABSTRACTProvision of enteral nutrition (EN) in hospitalized patients is an integral part of clinical care. For various reasons, including but not limited to delayed enteral access placement and EN initiation, it is becoming more prevalent for registered dietitians (RDs) to place feeding tubes in various clinical settings. Although numerous RDs have expanded their practice by learning this skill, many remain hesitant about adding feeding tube placement to their scope of responsibilities. Feeding tube placement is within RDs' scope of practice. The r...
Source: Nutrition in Clinical Practice - September 19, 2023 Category: Nutrition Authors: Maryam Yeganehjoo Jennifer Johanek Source Type: research
