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Total 54633 results found since Jan 2013.
Evaluating the Dissemination and Implementation Impact of a Rehabilitation Intervention: The Graded Repetitive Arm Supplementary Program (GRASP)
CONCLUSION: The Payback Framework is useful to evaluate the dissemination and implementation impacts of a rehabilitation intervention. GRASP has been implemented extensively in clinical practice and community in a relatively short time since it has been developed.PMID:37736384 | PMC:PMC10510554 | DOI:10.3138/ptc-2022-0117
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Chieh-Ling Yang Louise A Connell Janice J Eng Source Type: research
Artificial Intelligence for Drug Discovery: Are We There Yet?
Annu Rev Pharmacol Toxicol. 2023 Sep 22. doi: 10.1146/annurev-pharmtox-040323-040828. Online ahead of print.ABSTRACTDrug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug discovery, as indicated by increasing interest from investors, industrial and academic scientists, and legislators. Successful drug discovery requires optimizing properties related to pharmacodynamics, pharmacokinetics, and clinical outcomes. This review discusses the use of AI in ...
Source: Annual Review of Pharmacology and Toxicology - September 22, 2023 Category: Drugs & Pharmacology Authors: Catrin Hasselgren Tudor I Oprea Source Type: research
Clinical trials in Charcot-Marie-Tooth disorders: a retrospective and preclinical assessment
ConclusionCurrent CMT trials are exploring procedural and molecular therapeutic options with substantial participation of the pharmaceutical industry worldwide. Emerging drug therapies directed at molecular pathogenesis are being advanced in human clinical trials; however, the majority remain within animal investigations.
Source: Frontiers in Neurology - September 22, 2023 Category: Neurology Source Type: research
Are Social Deprivation and Low Traditional Health Literacy Associated With Higher PROMIS CAT Completion in Orthopaedic Surgery?
CONCLUSION: Within an urban, socioeconomically diverse, orthopaedic patient population, health literacy was associated with PROMIS CAT questionnaire completion. Lower health literacy levels increased the likelihood of not completing any part of the assigned PROMIS CAT questionnaires. Additionally, patients completed PROMIS CAT without fully understanding the questions. This indicates that patient completion does not guarantee comprehension of the questions nor validity of their scores, even more so among patients with low health literacy. This is a substantive concern for fidelity of data gathered from PROMIS CAT.CLINICAL ...
Source: Clinical Orthopaedics and Related Research - September 21, 2023 Category: Orthopaedics Authors: Audrey L Litvak Nicholas A Lin Kelly K Hynes Jason A Strelzow Megan A Conti Mica Jeffrey G Stepan Source Type: research
Existing Nongated CT Coronary Calcium Predicts Operative Risk in Patients Undergoing Noncardiac Surgeries (ENCORES)
CONCLUSIONS: Prevalence and severity of coronary calcium obtained from existing nongated chest CT imaging improve preoperative clinical risk stratification before nongated surgery.PMID:37732454 | DOI:10.1161/CIRCULATIONAHA.123.064398
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Daniel Y Choi Dena Hayes Samuel D Maidman Nehal Dhaduk Jill E Jacobs Anna Shmukler Jeffrey S Berger Germaine Cuff David Rehe Mitchell Lee Robert Donnino Nathaniel R Smilowitz Source Type: research
Health data ecosystem in Pakistan: a multisectoral qualitative assessment of needs and opportunities
CONCLUSIONS: Our study identified key areas of focus that can contribute to orient a national health data roadmap and ecosystem in Pakistan.PMID:37734897 | DOI:10.1136/bmjopen-2023-071616
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Sana Mahmood Ali Aahil Noorali Afshan Manji Noreen Afzal Saadia Abbas Javeria Bilal Qamar Sameen Siddiqi Zahra Hoodbhoy Salim S Virani Zulfiqar A Bhutta Zainab Samad Source Type: research
Existing Nongated CT Coronary Calcium Predicts Operative Risk in Patients Undergoing Noncardiac Surgeries (ENCORES)
CONCLUSIONS: Prevalence and severity of coronary calcium obtained from existing nongated chest CT imaging improve preoperative clinical risk stratification before nongated surgery.PMID:37732454 | DOI:10.1161/CIRCULATIONAHA.123.064398
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Daniel Y Choi Dena Hayes Samuel D Maidman Nehal Dhaduk Jill E Jacobs Anna Shmukler Jeffrey S Berger Germaine Cuff David Rehe Mitchell Lee Robert Donnino Nathaniel R Smilowitz Source Type: research
Involving patients and the public in nursing PhD projects: practical guidance, potential benefits and points to consider
CONCLUSION: Patients and the public should be involved in nursing PhD projects. Not only does this improve the quality of the research and raise the profile of nursing research, but it provides the opportunity for students to learn skills that they can develop further throughout their academic careers.IMPLICATIONS FOR PRACTICE: Obtaining high-quality patient and public involvement is an important skill for nurse researchers. The first steps in acquiring this skill should be taken during research training.PMID:37731298 | DOI:10.7748/nr.2023.e1891
Source: Nurse Researcher - September 21, 2023 Category: Nursing Authors: Chris McParland Bridget Johnston Bahaa Alassoud Maria Drummond Annabel Farnood Chandra Isabella Hostanida Purba Muzeyyen Seckin Saengrawee Thanthong Source Type: research
Athletic Trainers' Observations of Social Determinants of Health in the Collegiate Setting: A Card Study
CONCLUSIONS: Because ATs are positioned to accurately assess SDH, they can promote better patient-centered care and improve patient outcomes. Our results suggested many SDH observed by ATs in the college/university setting had a negative influence on patient health. Better support for patients with behavioral health issues and academic stressors is important because these SDH were commonly perceived to negatively influence health and well-being.PMID:37734734 | DOI:10.4085/1062-6050-0327.23
Source: J Athl Train - September 21, 2023 Category: Sports Medicine Authors: Kelsey J Picha Cailee E Welch Bacon Cassidy Evans Windsor Joy Lewis Alison R Snyder Valier Source Type: research
Remote Monitoring Compared With In-Office Surveillance of Blood Pressure in Patients With Pregnancy-Related Hypertension: A Randomized Controlled Trial
CONCLUSION: Remote monitoring can increase postpartum blood pressure ascertainment within 10 days of discharge for women with hypertensive disorders of pregnancy and has the potential to promote health equity.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04823949.PMID:37734091 | DOI:10.1097/AOG.0000000000005327
Source: Obstetrics and Gynecology - September 21, 2023 Category: OBGYN Authors: Brittany J Arkerson Matthew M Finneran Solita R Harris Jessica Schnorr Eliza R McElwee Lauren Demosthenes Renata Sawyer Source Type: research
Addiction and Volitional Abilities: Stakeholders ’ Understandings and their Ethical and Practical Implications
AbstractAddiction is a common condition affecting millions of people worldwide of which only a small proportion receives treatment. The development and use of healthcare services is influenced by how addiction is understood (e.g., a condition to treat, a shameful condition to stigmatize), notably with respect to how volition is impacted (e.g., addiction as a choice or a disease beyond one ’s control). Through semi-structured qualitative interviews, we explore the implicit views and understandings of addiction and volition across three stakeholder groups: people with lived experience of addiction, clinicians with experien...
Source: Neuroethics - September 21, 2023 Category: Medical Ethics Source Type: research
Mindfulness for academic performance in health professions students: a systematic review
Discussion
Our systematic review highlights a lack of evidence to either support, or refute, the use of mindfulness interventions on the academic performance of undergraduate medical students. We encourage that future randomised controlled trials pay heed to the dosing of mindfulness and include a measurement of mindfulness to enable us to draw a clearer causal relationship.
Source: Evidence-Based Medicine - September 21, 2023 Category: Internal Medicine Authors: Balasooriya Lekamge, R., Gasevic, D., Karim, M. N., Ilic, D. Tags: General Medicine Evidence synthesis Source Type: research
Studying Emotion Regulation Success in Daily Life: Distinctions From Maladaptive Regulation and Dysregulation
Pers Soc Psychol Rev. 2023 Sep 20:10888683231199140. doi: 10.1177/10888683231199140. Online ahead of print.ABSTRACTACADEMIC ABSTRACT: This paper aims to motivate research on emotion regulation success in naturalistic settings. We define emotion regulation success as achieving one's emotion regulation goal and differentiate it from related concepts (i.e., maladaptive regulation and dysregulation). As goals vary across individuals and situations, it is insufficient to conceptualize emotion regulation success as maximizing positive affect and minimizing negative affect. Instead, emotion regulation success can be measured thro...
Source: Personality and Social Psychology Review - September 20, 2023 Category: Psychiatry & Psychology Authors: Tabea Springstein Tammy English Source Type: research
An examination of willingness to participate and willingness to pay for a universal school food program in the Canadian context
CONCLUSION: A cost shared program might be financially sustainable in Canada if community characteristics such as household food insecurity status, economic participation of women and average household size are kept in mind while determining the price of the program.PMID:37728040 | DOI:10.1017/S1368980023002070
Source: Public Health Nutrition - September 20, 2023 Category: International Medicine & Public Health Authors: Suvadra Datta Gupta Punam Pahwa Rachel Engler-Stringer Source Type: research
Industry updates from the field of stem cell research and regenerative medicine in July 2023
Regen Med. 2023 Sep 20. doi: 10.2217/rme-2023-0177. Online ahead of print.ABSTRACTLatest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from non-academic institutions in July 2023.PMID:37727975 | DOI:10.2217/rme-2023-0177
Source: Regenerative Medicine - September 20, 2023 Category: Genetics & Stem Cells Authors: Dusko Ilic Mirjana Liovic Source Type: research
