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Total 5394 results found since Jan 2013.
Antimicrobial resistance of Pseudomonas aeruginosa isolated from patients with pneumonia during the COVID-19 pandemic and pre-pandemic periods in Northeast Brazil
Braz J Med Biol Res. 2023 Jul 21;56:e12726. doi: 10.1590/1414-431X2023e12726. eCollection 2023.ABSTRACTHealthcare-related infections caused by resistant microorganisms are a severe public health problem and are becoming increasingly prevalent in the hospital environment, especially Pseudomonas aeruginosa. This work aimed to evaluate the resistance profile of Pseudomonas aeruginosa to antimicrobials before the COVID-19 pandemic and during the pandemic period. Bacteria strains were obtained from tracheal aspiration, sputum, and bronchoalveolar lavage for diagnosis and phenotypic characterization. Matrix assisted laser-desorp...
Source: Braz J Med Biol Res - July 26, 2023 Category: Research Authors: G P Mesquita M C C Costa M A Silva L G Ara újo B G Vila Nova É J M Castro L C M Castelo Branco R C S da Silva S G Marques A G Abreu Source Type: research
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease
Mini Rev Med Chem. 2023 Jul 25. doi: 10.2174/1389557523666230725115324. Online ahead of print.ABSTRACTAlongside the prescription of commonly used antivirals, such as acyclovir, remdesivir, oseltamivir, and ciprofloxacin, the most efficient way to prevent or treat communicable diseases is by vaccination. Vaccines have been the most efficient way to prevent or treat highly transmissible infectious agents, such as Ebola, Anthrax, and Dengue Fever. Most epidemics of these highly transmissible infectious agents occur in places, such as South America, Central America, Tropical Asia, and Africa, where the availability of resource...
Source: Mini Reviews in Medicinal Chemistry - July 25, 2023 Category: Chemistry Authors: Anthony Garcia Oliver Grundmann Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 Jul 24:1-14. doi: 10.1080/08927014.2023.2232722. Online ahead of print.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers and c...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
