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Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
Adsorptive removal of ciprofloxacin and sulfamethoxazole from aqueous matrices using sawdust and plastic waste-derived biochar: A sustainable fight against antibiotic resistance
Bioresour Technol. 2023 Jul 22:129537. doi: 10.1016/j.biortech.2023.129537. Online ahead of print.ABSTRACTWe produced carbon-negative biochar from the pyrolysis of sawdust biomass alone (SB) and from the co-pyrolysis of sawdust and plastic waste (SPB). The co-pyrolysis approach in this study was driven by several hypothetical factors, such as increased porosity, surface chemistry, stability, as well as waste management. We applied pyrolyzed and co-pyrolyzed biochars for the removal of ciprofloxacin (CFX) and sulfamethoxazole (SMX). Although SB biochar, due to its more alkaline and amorphous nature, showed better removal ef...
Source: Bioresource Technology - July 24, 2023 Category: Biotechnology Authors: Rahul Silori Jian Zang Nirav P Raval Balendu Shekher Giri J ürgen Mahlknecht Abrahan Mora Jaime Due ñas-Moreno Syed Mohammad Tauseef Manish Kumar Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 Jul 24:1-14. doi: 10.1080/08927014.2023.2232722. Online ahead of print.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers and c...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
Adsorptive removal of ciprofloxacin and sulfamethoxazole from aqueous matrices using sawdust and plastic waste-derived biochar: A sustainable fight against antibiotic resistance
Bioresour Technol. 2023 Jul 22:129537. doi: 10.1016/j.biortech.2023.129537. Online ahead of print.ABSTRACTWe produced carbon-negative biochar from the pyrolysis of sawdust biomass alone (SB) and from the co-pyrolysis of sawdust and plastic waste (SPB). The co-pyrolysis approach in this study was driven by several hypothetical factors, such as increased porosity, surface chemistry, stability, as well as waste management. We applied pyrolyzed and co-pyrolyzed biochars for the removal of ciprofloxacin (CFX) and sulfamethoxazole (SMX). Although SB biochar, due to its more alkaline and amorphous nature, showed better removal ef...
Source: Bioresource Technology - July 24, 2023 Category: Biotechnology Authors: Rahul Silori Jian Zang Nirav P Raval Balendu Shekher Giri J ürgen Mahlknecht Abrahan Mora Jaime Due ñas-Moreno Syed Mohammad Tauseef Manish Kumar Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 Jul 24:1-14. doi: 10.1080/08927014.2023.2232722. Online ahead of print.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers and c...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 Jul 24:1-14. doi: 10.1080/08927014.2023.2232722. Online ahead of print.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers and c...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 Jul 24:1-14. doi: 10.1080/08927014.2023.2232722. Online ahead of print.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers and c...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 May-Jul;39(5):502-515. doi: 10.1080/08927014.2023.2232722. Epub 2023 Jul 24.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers ...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
Thermal susceptibility and antibiotic synergism of methicillin-resistant < em > Staphylococcus aureus < /em > biofilms
This study investigated the thermal susceptibility of MRSA biofilms to thermal shocks from 60 to 80 °C for 1-30 min as well as the effect of various antibiotics (most notably methicillin) on thermal mitigation. Pre- and post-shock exposure to three different classes of antibiotics (ciprofloxacin, tobramycin, and methicillin) at concentrations ranging from 0.25 to 128 μg mL-1 were investigated. MRSA biofilms exhibited thermal susceptibility comparable to other common nosocomial pathogens, such as Pseudomonas aeruginosa, though with greater variability. Exposure to antibiotics of any class significantly decreased the degre...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Haydar A S Aljaafari Parham Parnian Jaymes Van Dyne Eric Nuxoll Source Type: research
An antimicrobial metabolite n- hexadecenoic acid from marine sponge-associated bacteria < em > Bacillus subtilis < /em > effectively inhibited biofilm forming multidrug-resistant < em > P. aeruginosa < /em >
Biofouling. 2023 May-Jul;39(5):502-515. doi: 10.1080/08927014.2023.2232722. Epub 2023 Jul 24.ABSTRACTEffective drug candidates to obstruct the emergence of multidrug-resistant pathogens have become a major concern. A potent antimicrobial producer was isolated from a marine sponge designated as MSI38 and was identified as Bacillus subtilis by 16SrDNA sequencing. The active antimicrobial fraction was purified, and the metabolite was identified as n-hexadecanoic acid by spectroscopic analysis. The fish-borne pathogen Pseudomonas aeruginosa FP012 was found to be multidrug-resistant and poses a risk of disease to food handlers ...
Source: Biofouling - July 24, 2023 Category: Molecular Biology Authors: Arya Sajayan Amrudha Ravindran Joseph Selvin Prathiviraj Ragothaman George Seghal Kiran Source Type: research
