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Drug: Insulin
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Total 1848 results found since Jan 2013.
Steady solution and its stability of a mathematical model of diabetic atherosclerosis
J Biol Dyn. 2023 Dec;17(1):2257734. doi: 10.1080/17513758.2023.2257734.ABSTRACTAtherosclerosis is a leading cause of death worldwide. Making matters worse, nearly 463 million people have diabetes, which increases atherosclerosis-related inflammation. Diabetic patients are twice as likely to have a heart attack or stroke. In this paper, we consider a simplified mathematical model for diabetic atherosclerosis involving LDL, HDL, glucose, insulin, free radicals (ROS), β cells, macrophages and foam cells, which satisfy a system of partial differential equations with a free boundary, the interface between the blood flow and th...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Xuming Xie Source Type: research
Potentially Inappropriate Medication Use Among Older Patients with
Diabetes in a Chinese Community
Conclusions Given the higher rate of PIM use among older adults with
diabetes, strategies and interventions targeting this population are needed to
minimize PIM use. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Experimental and Clinical Endocrinology and Diabetes - September 6, 2023 Category: Endocrinology Authors: Zhao, Xingxing Li, Lei Guo, Xiujun Wang, Jianqiang Yan, Yingying Le, Yunyi Tags: Article Source Type: research
Glutamate infusion reduces myocardial dysfunction after coronary artery bypass grafting according to NT-proBNP: summary of two randomized controlled trials (GLUTAMICS I-II)
CONCLUSIONS: Infusion of glutamate reduced postoperative rise in NT-proBNP after CABG in medium to high-risk patients. A significantly blunted effect was observed only in insulin-treated diabetes patients.CLINICAL TRIAL REGISTRATION: NCT02592824, https://clinicaltrials.gov/ct2/show/NCT02592824.PMID:37657522 | DOI:10.1016/j.ajcnut.2023.08.012
Source: The American Journal of Clinical Nutrition - September 1, 2023 Category: Nutrition Authors: Jonas Holm Farkas Vanky Rolf Svedjeholm Source Type: research
Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications
Am J Chin Med. 2023 Aug 30:1-39. doi: 10.1142/S0192415X23500775. Online ahead of print.ABSTRACTDiabetes mellitus (DM) has become a surge burden worldwide owing to its high prevalence and range of associated complications such as coronary artery disease, blindness, stroke, and renal failure. Accordingly, the treatment and management of DM have become a research hotspot. Mulberry leaves (Morus alba L.) have been used in Traditional Chinese Medicine for a long time, with the first record of its use published in Shennong Bencao Jing (Shennong's Classic of Materia Medica). Mulberry leaves (MLs) are considered highly valuable me...
Source: The American Journal of Chinese Medicine - August 30, 2023 Category: Complementary Medicine Authors: Yanjiao Zhang Runyu Miao Kaile Ma Yuxin Zhang Xinyi Fang Jiahua Wei Ruiyang Yin Jingxue Zhao Jiaxing Tian Source Type: research
Insulin resistance estimated by estimated glucose disposal rate predicts outcomes in acute ischemic stroke patients
In this study, we...
Source: Cardiovascular Diabetology - August 26, 2023 Category: Cardiology Authors: Zhengzhao Lu, Yunyun Xiong, Xueyan Feng, Kaixuan Yang, Hongqiu Gu, Xingquan Zhao, Xia Meng and Yongjun Wang Tags: Research Source Type: research
Circular RNA ciRS-7 signature as a potential biomarker for the early detection of diabetes with Alzheimer's disease: a hypothesis
Mol Biol Rep. 2023 Aug 24. doi: 10.1007/s11033-023-08729-2. Online ahead of print.ABSTRACTIn the 1970s, Circular RNAs (CircRNAs) were first discovered in RNA viruses as viroids and were initially assumed to be RNA splicing defects. The roles and topologies of these circular RNA loops were later revealed using computer analysis and RNA-sequencing. They were found to demonstrate various functions, including protein scaffolding, parental gene regulation, microRNA sponges, and RNA-protein interactions. CircRNAs play a crucial role in controlling gene expression and are essential for biological development and illness detection...
Source: Molecular Biology Reports - August 24, 2023 Category: Molecular Biology Authors: Mahima Singh Ajay Guru Raghul Murugan Muthukaruppan Gopi Jesu Arockiaraj Source Type: research
Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
CONCLUSION: Aging accelerates beta cell senescence by generating premature cell senescence, which is mostly mediated by high glucose levels. Despite higher plasma glucose levels, hepatic gluconeogenesis accelerates and adipose tissue lipolysis rises, resulting in an increase in free fatty acid levels in the blood and worsening insulin resistance throughout the body.PMID:37608675 | DOI:10.2174/1871530323666230822095932
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 23, 2023 Category: Endocrinology Authors: Rishabh Chaudhary Janvi Khanna Manni Rohilla Sumeet Gupta Seema Bansal Source Type: research
Hyperosmolar Hyperglycemic State
Hyperosmolar hyperglycemic state (HHS) is an underrecognized diabetic emergency with high morbidity and mortality. Many features of HHS overlap with those of diabetic ketoacidosis but key differentiators for HHS are serum osmolality greater than 320 mOsm/kg, lack of metabolic acidosis, and minimal to no presence of ketones. HHS is often triggered by an underlying illness —most commonly infection but may also be triggered by stroke, acute coronary syndrome, and other acute illnesses. Treatment guidelines recommend aggressive volume-repletion of osmotic losses in addition to insulin therapy, plus treatment of the underlying cause.
Source: Emergency Medicine Clinics of North America - August 18, 2023 Category: Emergency Medicine Authors: Spencer S. Lovegrove, Sarah B. Dubbs Source Type: research
