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Acute bacterial infection negatively impacts cancer specific survival of colorectal cancer patients.
CONCLUSION: Infection and high neutrophil counts are associated with a poorer cancer-specific survival in colorectal cancer patients. PMID: 25320529 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - October 14, 2014 Category: Gastroenterology Authors: Attiê R, Chinen LT, Yoshioka EM, Silva MC, de Lima VC Tags: World J Gastroenterol Source Type: research

Increased Stroke Risk Among Adult Asthmatic Patients
ConclusionAsthma may be an independent risk factor for stroke, and its severity exhibits a dose response of stroke development.This article is protected by copyright. All rights reserved.
Source: European Journal of Clinical Investigation - September 10, 2014 Category: Journals (General) Authors: Wei‐Sheng Chung, Cheng‐Li Lin, Yung‐Fu Chen, Feng‐Ming Ho, Wu‐Huei Hsu, Chia‐Hung Kao Tags: Original Article Source Type: research

Incidence, risk factors and outcomes of stroke post‐transplantation in patients receiving a steroid sparing immunosuppression protocol
This article is protected by copyright. All rights reserved.
Source: Clinical Transplantation - September 1, 2014 Category: Transplant Surgery Authors: Michelle Willicombe, Nicola Kumar, Dawn Goodall, Candice Clarke, Adam G McLean, Albert Power, David Taube Tags: Original Article Source Type: research

Steroid treatment can improve the impaired quality of life of patients with acquired idiopathic generalized anhidrosis
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - July 24, 2014 Category: Dermatology Authors: A. Fukunaga, M. Hatakeyama, M. Tsujimoto, Y. Oda, K. Washio, C. Nishigori Tags: Correspondence Source Type: research

Steroid treatment can improve the impaired quality of life of patients with acquired idiopathic generalized anhidrosis.
This article is protected by copyright. All rights reserved. PMID: 25060903 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - July 24, 2014 Category: Dermatology Authors: Fukunaga A, Hatakeyama M, Tsujimoto M, Oda Y, Washio K, Nishigori C Tags: Br J Dermatol Source Type: research

Study shows insufficient decrease in wound complications with sutured versus stapled skin closure in gastrointestinal operations
Commentary on: Tsujinaka T, Yamamoto K, Fujita J, et al.. Subcuticular sutures versus staples for skin closure after open gastrointestinal surgery: a phase 3, multicentre, open-label, randomised controlled trial. Lancet 2013;382:1105–12. Context Postoperative wound complications can occur in 9–26% of gastrointestinal operations.1–3 Skin closure with subcuticular sutures in clean operations, such as caesarean sections, are associated with decreased wound complications and increased patient satisfaction when compared with skin closure using staples.4 5 Whether these results are applicable to clean–con...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Vo, H., Kin, C. Tags: Patients, Clinical trials (epidemiology), Immunology (including allergy), Drugs: cardiovascular system, Stroke, Dermatology, Diabetes, Injury Therapeutics Source Type: research

Is Intracranial Arterial Involvement A Subgroup of Neuro-Behcet Syndrome? (P5.035)
Conclusion:Neurological involvement in BS patients is generally due to venous inflammation. Intracranial arterial involvement in NBS is rare, but it should be kept in mind that it can occur during the course of the disease independent of other stroke risk factors.Disclosure: Dr. Zeydan has nothing to disclose. Dr. Uygunoglu has received personal compensation for activities with Merck Serono, Biogen Idec, Novartis and Allergan Inc. as an attendee at congresses or symposia. Dr. Tutuncu has nothing to disclose. Dr. Yalcinkaya has nothing to disclose. Dr. Altintas has received personal compensation for activities with The Scie...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Zeydan, B., Uygunoglu, U., Tutuncu, M., Yalcinkaya, C., Altintas, A., Saipoglu, S., Siva, A. Tags: General Neurology IV Source Type: research

Paroxysmal Dysarthria and Ataxia after Treatment of Brainstem Encephalitis (P6.053)
CONCLUSIONS: Paroxysmal dysarthria and ataxia is most often recognized as a complication of multiple sclerosis, but it can occur in other neurologic diseases with midbrain lesions near or involving the red nucleus. Effective treatments include carbamazepine, acetazolamide, lamotrigine, and phenytoin.Study Supported by: N/A.Disclosure: Dr. Klaas has nothing to disclose. Dr. Boes has nothing to disclose. Dr. Aksamit has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Klaas, J., Boes, C., Aksamit, A. Tags: Movement Disorders: Miscellaneous Ataxias Source Type: research

Increased risk of atrial fibrillation and stroke during active stages of inflammatory bowel disease: a nationwide study
Conclusion Active IBD is associated with increased risk of AF and stroke. These findings may be relevant to clinical practice.
Source: Europace - April 7, 2014 Category: Cardiology Authors: Kristensen, S. L., Lindhardsen, J., Ahlehoff, O., Erichsen, R., Lamberts, M., Khalid, U., Torp-Pedersen, C., Nielsen, O. H., Gislason, G. H., Hansen, P. R. Tags: Atrial fibrillation Source Type: research

Factors Associated with Major Cardiovascular Events in Patients with Systemic Necrotizing Vasculitides: Results of a Longterm Followup Study.
CONCLUSION: These results suggest that factors associated with a higher MCVE risk in patients with SNV are NCEP/ATP III-defined high-risk status and BMI > 30 kg/m(2). Carotid IMT could help identify patients with SNV at risk of early MCVE. PMID: 24584925 [PubMed - as supplied by publisher]
Source: J Rheumatol - March 1, 2014 Category: Rheumatology Authors: Terrier B, Chironi G, Pagnoux C, Cohen P, Puéchal X, Simon A, Mouthon L, Guillevin L, for the French Vasculitis Study Group Tags: J Rheumatol Source Type: research

Targeting Microglial Activation in Stroke Therapy: Pharmacological Tools and Gender Effects.
Abstract Ischemic stroke is caused by critical reductions in blood flow to a part of brain or spinal cord. Microglia are the resident immune cells of the central nervous system, and they respond to stroke by assuming an activated phenotype that releases cytotoxic cytokines, reactive oxygen species, proteases, and other factors. This acute, innate immune response may be teleologically adapted to limit infection, but in stroke this response can exacerbate injury by further damaging or killing nearby neurons and other cell types and by recruiting infiltration of circulating cytotoxic immune cells. The microglial resp...
Source: Current Medicinal Chemistry - December 28, 2013 Category: Chemistry Authors: Chen Y, Won SJ, Xu Y, Swanson RA Tags: Curr Med Chem Source Type: research

Mortality of bullous pemphigoid in Singapore: risk factors and causes of death in 359 patients seen at the National Skin Centre.
CONCLUSION: This study confirmed an increased 3-year mortality rate for BP patients in Singapore. Risk factors for increased mortality include medical co-morbidities, especially neurological, cardiac and renal diseases. Treatment with combination therapy, including the use of low to moderate dose corticosteroid, appeared to decrease mortality risk in BP patients. This article is protected by copyright. All rights reserved. PMID: 24372558 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - December 24, 2013 Category: Dermatology Authors: Cai SC, Allen JC, Lim YL, Chua SH, Tan SH, Tang MB Tags: Br J Dermatol Source Type: research

Mortality of bullous pemphigoid in Singapore: risk factors and causes of death in 359 patients seen at the National Skin Centre
ConclusionThis study confirmed an increased 3‐year mortality rate for BP patients in Singapore. Risk factors for increased mortality include medical co‐morbidities, especially neurological, cardiac and renal diseases. Treatment with combination therapy, including the use of low to moderate dose corticosteroid, appeared to decrease mortality risk in BP patients.This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - December 1, 2013 Category: Dermatology Authors: S.C.S. Cai, J.C. Allen, Y.L. Lim, S.H. Chua, S.H. Tan, M.B.Y. Tang Tags: Original Article Source Type: research

C-reactive protein and fracture risk: European Prospective Investigation into Cancer Norfolk Study
Conclusion: A U-shaped association was observed between CRP and fracture risk. The increased risk of fracture observed at lower end of CRP compared to intermediate levels require further exploration, confirmation in other populations, and investigation into potential biological mechanisms.Highlights:
Source: Bone - July 17, 2013 Category: Orthopaedics Authors: Sara Ahmadi-Abhari, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw Tags: Original Articles Source Type: research

Internal carotid thrombus in patients with inflammatory bowel disease: Two cases.
We report 2 cases of ischemic strokes due to internal carotid thrombus in patients during active phase of IBD. Ulceration of early atherosclerotic plaques activated by a hypercoagulation state may cause a thrombus. A combined therapy with heparin and corticosteroids was used for both our patients. Lysis of the thrombus was obtained after several days without surgical treatment and shown by ultrasonography. These cases highlight an aetiology of stroke in patients with IBD and use of a synergic treatment to respond to hypercoagulability in link with IBD. Benefits and safety of this therapy should be confirmed with clinical s...
Source: World Journal of Gastroenterology : WJG - February 7, 2013 Category: Gastroenterology Authors: Richard S, Mione G, Perrin J, Toussaint-Hacquard M, Lacour JC, Ducrocq X Tags: World J Gastroenterol Source Type: research

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