Filtered By:
Specialty: Microbiology

This page shows you your search results in order of date.

Order by Relevance | Date

Total 99 results found since Jan 2013.

Gut microbiota and cerebrovascular diseases: a Mendelian randomization study
ConclusionThis MR analysis indicates that there exists a beneficial or detrimental causal effect of gut microbiota composition on cerebrovascular disease. And SBP and T2D may play mediating role in this process.
Source: Frontiers in Microbiology - August 10, 2023 Category: Microbiology Source Type: research

A study of the correlation between stroke and gut microbiota over the last 20years: a bibliometric analysis
ConclusionFindings suggest that in the next 10 years, the number of publications produced annually may increase significantly. Future research trends tend to concentrate on the mechanisms of stroke and gut microbiota, with the inflammation and immunological mechanisms, TMAO, and fecal transplantation as hotspots. And the relationship between these mechanisms and a particular cardiovascular illness may also be a future research trend.
Source: Frontiers in Microbiology - June 7, 2023 Category: Microbiology Source Type: research

Risk factors for small intestinal bacterial overgrowth in patients with acute ischaemic stroke
Conclusion. The prevalence of SIBO in patients with AIS was 28.8 %. TG and Hcy levels are independent risk factors for SIBO in patients with AIS. Both markers had good predictive value for the occurrence of SIBO. In the future, we should actively utilize these indicators to prevent intestinal flora imbalance and the occurrence of SIBO.PMID:36762525 | DOI:10.1099/jmm.0.001666
Source: Journal of Medical Microbiology - February 10, 2023 Category: Microbiology Authors: Yang Liu Min Chu Daosheng Wang Yunhe Luo Zhuohang Liu Jing Zhao Source Type: research

The roles and mechanisms of gut microbiome and metabolome in patients with cerebral infarction
As the most common type of stroke, ischemic stroke, also known as cerebral infarction (CI), with its high mortality and disability rate, has placed a huge burden on social economy and public health. Treatment methods for CI mainly include thrombectomy, thrombolysis, drug therapy, and so on. However, these treatments have certain timeliness and different side effects. In recent years, the gut-brain axis has become a hot topic, and its role in nervous system diseases has been confirmed by increasing evidences. The intestinal microbiota, as an important part of the gut-brain axis, has a non-negligible impact on the progressio...
Source: Frontiers in cellular and infection microbiology - January 25, 2023 Category: Microbiology Source Type: research

Multi-omics reveals specific host metabolism-microbiome associations in intracerebral hemorrhage
In conclusion, microbiome-related metabolites in ICH patients was associated with the severity of ICH, the microbiota-host co-metabolites may be a potential may be potential therapeutic targets.
Source: Frontiers in cellular and infection microbiology - December 22, 2022 Category: Microbiology Source Type: research

Gut microbiota signature as predictors of adverse outcomes after acute ischemic stroke in patients with hyperlipidemia
ConclusionsThese findings revealed the microbial characteristics of POAH, which highlighted the predictive capability of characteristic microbiota in POAH patients.
Source: Frontiers in cellular and infection microbiology - November 24, 2022 Category: Microbiology Source Type: research

Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia –reperfusion injury based on integrating fecal metabonomics and 16S rDNA sequencing
Gastrodia elata Blume was used to treat stroke and headaches caused by “Feng” for thousands of years. The present study has shown a significant effect of G. elata Blume in improving cerebral ischemia–reperfusion injury (CIRI). However, the mechanism of G. elata Blume in improving CIRI by regulating the intestinal flora has not been reported until now. This research aimed to comprehensively evaluate the mechanism of G. elata Blume in CIRI based on fecal metabolomics and 16S rDNA sequencing. The rat model with CIRI was created based on the Zea Longa method. Enzyme-linked immunosorbent assay (ELISA) was used to monitor ...
Source: Frontiers in cellular and infection microbiology - October 27, 2022 Category: Microbiology Source Type: research

F1FO ATP synthase molecular motor mechanisms
The F-ATP synthase, consisting of F1 and FO motors connected by a central rotor and the stators, is the enzyme responsible for synthesizing the majority of ATP in all organisms. The F1 (αβ)3 ring stator contains three catalytic sites. Single-molecule F1 rotation studies revealed that ATP hydrolysis at each catalytic site (0°) precedes a power-stroke that rotates subunit-γ 120° with angular velocities that vary with rotational position. Catalytic site conformations vary relative to subunit-γ position (βE, empty; βD, ADP bound; βT, ATP-bound). During a power stroke, βE binds ATP (0°–60°) and βD releases ADP (6...
Source: Frontiers in Microbiology - August 23, 2022 Category: Microbiology Source Type: research

The Gut Microbiota (Microbiome) in Cardiovascular Disease and Its Therapeutic Regulation
In the last two decades, considerable interest has been shown in understanding the development of the gut microbiota and its internal and external effects on the intestine, as well as the risk factors for cardiovascular diseases (CVDs) such as metabolic syndrome. The intestinal microbiota plays a pivotal role in human health and disease. Recent studies revealed that the gut microbiota can affect the host body. CVDs are a leading cause of morbidity and mortality, and patients favor death over chronic kidney disease. For the function of gut microbiota in the host, molecules have to penetrate the intestinal epithelium or the ...
Source: Frontiers in cellular and infection microbiology - June 20, 2022 Category: Microbiology Source Type: research

Epidemiologic and Genomic Analysis of the Severe Acute Respiratory Syndrome Coronavirus 2 Epidemic in the Nebraska Region of the United States, March 2020 –2021
This report details the epidemiologic and genetic evolution of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first year of the epidemic in the state of Nebraska using data collected from the Creighton Catholic Health Initiatives (CHI) health system. Statistical modelling identified age, gender, and previous history of diabetes and/or stroke as significant risk factors associated with mortality in COVID-19 patients. In parallel, the viral genomes of over 1,000 samples were sequenced. The overall rate of viral variation in the population was 0.07 mutations/day. Genetically, the first 9 months of...
Source: Frontiers in Microbiology - May 18, 2022 Category: Microbiology Source Type: research

Neuroinflammation, Sleep, and Circadian Rhythms
Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa. Sleep-inducing inflammatory molecules are activated by increased waking activity and pathogens. Pathologies that alter inflammatory molecules, such as traumatic brain injury, cancer, cardiovascular disease, and stroke often are associated with disturbed sleep and electroencephalogram power spectra. Moreover, sleep disorders, such as insomnia and sleep disordered breathing, are associated with increased dysregulation of inflammatory processes. Inflammatory molecules in both the central nervous system and periphery can alter sleep. I...
Source: Frontiers in cellular and infection microbiology - March 22, 2022 Category: Microbiology Source Type: research

Brain abscess mimicking acute stroke syndrome caused by dual Filifactor alocis and Porphyromonas gingivalis infections: A case report
Anaerobe. 2022 Feb 18:102535. doi: 10.1016/j.anaerobe.2022.102535. Online ahead of print.ABSTRACTThis case report is about a woman who had a brain abscess in the left parietal lobe that atypically presented as acute stroke-like syndrome. Pus samples from brain abscess aspiration revealed the periodontal pathogens Porphyromonas gingivalis and Filifactor alocis. After dental health care and 8 weeks of combined antimicrobial therapy, the patient recovered completely.PMID:35189362 | DOI:10.1016/j.anaerobe.2022.102535
Source: Anaerobe - February 21, 2022 Category: Microbiology Authors: Pruettichai Wisutep Witchuda Kamolvit Piriyaporn Chongtrakool Anupop Jitmuang Source Type: research