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Specialty: Cardiology
Procedure: Anesthesia

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Total 200 results found since Jan 2013.

Interventional closure of atrial septal defects, patent oval foramen and ventricular septal defects.
Authors: Hornung M, Franke J, Id D, Sievert H Abstract Percutaneous transcatheter closure techniques and devices for congenital intracardiac shunts have considerably improved; therefore, catheter closure is now the treatment of choice for atrial septal defects (ASD). This is technically feasible in more than 80 % of patients with a secundum ASD and the success rate is higher than 99 %. General anesthesia is as a rule unnecessary and the hospital stay is very short. A patent oval foramen (POF) is a potential cause of cryptogenic stroke and peripheral embolisms. The catheter occlusion has many advantages in compa...
Source: Herz - July 3, 2015 Category: Cardiology Tags: Herz Source Type: research

Transcatheter left atrial appendage closure using intracardiac echocardiographic guidance from the left atrium
Conclusion Initial experience suggests LAA occlusion with the Amplatzer Cardiac PlugTM under ICE guidance from the left atrium is feasible, reproducible and safe.
Source: Canadian Journal of Cardiology - May 18, 2015 Category: Cardiology Source Type: research

PP-148 Pediatric Atrial Septal Defect Closure Under General Anesthesia
Atrial septal defects (ASD) are present in about 1 in 1,500 children at birth and account for 30% to 40% of congenital heart disease in adults. ASD closure is usually performed for the prevention of stroke or right ventricular volume overload and pulmonary hypertension. Current American Heart Association guidelines recommend closure of ASDs for right atrial or right ventricular enlargement, paradoxic embolism, documented orthodeoxiaplatypnea and pulmonary hypertension. ASD closure results in symptomatic improvement and reductions in right ventricular size and pulmonary arterial pressures at any age.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Gökhan Özkan, Vedat Yıldırım, Mehmet Emın Ince, Suat Dogancı, Ayhan Kılıc Tags: Poster Abstract Source Type: research

Epidermal Growth Factor Receptor Is Critical For Angiotensin II-Mediated Hypertrophy in Cerebral Arterioles Renin-Angiotensin System
We examined the molecular mechanism of Ang II–mediated cerebrovascular remodeling that involves the epidermal growth factor receptor (EGFR) pathway. Mutant EGFR mice (waved-2), their heterozygous control (wild-type [WT]), and C57BL/6J mice were infused with Ang II (1000 ng kg–1 min–1) or saline via osmotic minipumps for 28 days (n=8 per group). Eight of the Ang II–infused C57BL/6J mice were cotreated with AG1478 (12 mg/kg per day, IP), a specific EGFR tyrosine kinase inhibitor. Systolic arterial pressure was measured by a tail-cuff method. Pressure and diameter of cerebral arterioles were measured t...
Source: Hypertension - March 11, 2015 Category: Cardiology Authors: Chan, S.-L., Umesalma, S., Baumbach, G. L. Tags: Cerebrovascular disease/stroke, Hypertrophy, Other Vascular biology Renin-Angiotensin System Source Type: research

Safety of Transcatheter Aortic Valve Implantation in a Hospital With Visiting On‐Site Cardiac Surgery
ConclusionsTAVI can be done safely in the setting of a hospital with visiting on‐site cardiac surgery. This requires careful patient selection, experienced operators and surgeons in experienced centers with well‐established criteria and processes of care. In this setting, it may be an option for hospitals without institutional cardiac surgery. (J Interven Cardiol 2015;28:76–81)
Source: Journal of Interventional Cardiology - February 16, 2015 Category: Cardiology Authors: SAMEER GAFOOR, MARGARITA SIROTINA, MIRKO DOSS, JENNIFER FRANKE, KERSTIN PIAYDA, SIMON LAM, STEFAN BERTOG, LAURA VASKELYTE, ILONA HOFMANN, HORST SIEVERT Tags: Original Investigation Source Type: research

Risk Stratification and Clinical Pathways to Optimize Length of Stay After Transcatheter Aortic Valve Replacement
Conclusions Excellent outcomes and decreased length of stay can be achieved with individualized risk stratification to select the optimal periprocedural practice and determine the timing of discharge. These findings should be further evaluated in a large long-term clinical study.
Source: Canadian Journal of Cardiology - December 9, 2014 Category: Cardiology Source Type: research

Left Atrial Appendage Closure With the Watchman™ Device
Conclusions Left atrial appendage closure with the WatchmanTM device is feasible and may be a good alternative therapy for stroke prevention in patients with atrial fibrillation and restrictions for anticoagulation.
Source: Revista Brasileira de Cardiologia Invasiva - November 26, 2014 Category: Cardiology Source Type: research

Reducing Door-to-Puncture Times for Intra-Arterial Stroke Therapy: A Pilot Quality Improvement Project Stroke
Conclusions In-hospital delays are a major obstacle to timely IAT. A simple approach for achieving substantial time savings is to mobilize the NI and anesthesia teams during patient evaluation and treatment decision making. This parallel workflow resulted in a >30-minute (25%) reduction in median door-to-puncture times.
Source: JAHA:Journal of the American Heart Association - November 11, 2014 Category: Cardiology Authors: Mehta, B. P., Leslie-Mazwi, T. M., Chandra, R. V., Bell, D. L., Sun, C.-H. J., Hirsch, J. A., Rabinov, J. D., Rost, N. S., Schwamm, L. H., Goldstein, J. N., Levine, W. C., Gupta, R., Yoo, A. J. Tags: Stroke Source Type: research

Short-Term Results of Transapical Transcatheter Mitral Valve Implantation for Mitral Regurgitation
ConclusionsTransapical transcatheter mitral valve implantation is technically feasible and can be performed safely. Early hemodynamic performance of the prosthesis was excellent. Transcatheter mitral valve implantation may become an important treatment option for patients with severe MR who are at high operative risk.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 20, 2014 Category: Cardiology Source Type: research

Cardiac responses to left ventricular pacing in hearts with normal electrical conduction: beneficial effect of improved filling is counteracted by dyssynchrony
In conclusion, pacing of the LV lateral wall increased LVEDV by displacing the septum rightward, suggesting a mechanism for a favorable effect of CRT in narrow QRS. The pacing, however, induced dyssynchrony and therefore reduced LV systolic function. These observations suggest that detrimental effects should be considered when applying CRT in patients with narrow QRS.
Source: AJP: Heart and Circulatory Physiology - August 1, 2014 Category: Cardiology Authors: Boe, E., Russell, K., Remme, E. W., Gjesdal, O., Smiseth, O. A., Skulstad, H. Tags: MUSCLE MECHANICS AND VENTRICULAR FUNCTION Source Type: research

Hemodynamic effects of etomidate, propofol and electrical shock in patients undergoing implantable cardioverter-defibrillator testing.
CONCLUSIONS: Propofol significantly decreased BP by both reducing cardiac output and causing vasodilatation whereas etomidate only slightly decreased dBP and mBP without affecting other parameters. Propofol-induced changes were independent of LVEF or NYHA class. Induction of VF and internal defibrillation did not cause clinically significant changes apart from very modest drop in dBP and mBP values. PMID: 24846355 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - May 20, 2014 Category: Cardiology Authors: Zgoła K, Kułakowski P, Czepiel A, Swiątkowski M, Makowska E, Błachnio E, Soszyńska M, Misiewicz M Tags: Kardiol Pol Source Type: research

PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial
Conclusion: Multispecialty community practice enrollment into a large pragmatic trial of diagnostic testing strategies is both feasible and efficient. The PROMISE trial will compare the clinical effectiveness of an initial strategy of functional testing against an initial strategy of anatomical testing in symptomatic patients with suspected CAD. Quality of life, resource use, cost-effectiveness, and radiation exposure will be assessed.
Source: American Heart Journal - March 20, 2014 Category: Cardiology Authors: Pamela S. Douglas, Udo Hoffmann, Kerry L. Lee, Daniel B. Mark, Hussein R. Al-Khalidi, Kevin Anstrom, Rowena J. Dolor, Andrzej Kosinski, Mitchell W. Krucoff, Daniel W. Mudrick, Manesh R. Patel, Michael H. Picard, James E. Udelson, Eric J. Velazquez, Lawton Tags: Trial Design Source Type: research

Assessment of right ventricular volumes in hypoplastic left heart syndrome by real-time three-dimensional echocardiography: comparison with cardiac magnetic resonance imaging
Conclusion Both 3D echocardiography and CMR volumes appear highly reproducible. Measurements obtained by 3D echocardiography are significantly lower than those obtained by CMR, with wide limits of agreement such that these two methods cannot be used inter-changeably.
Source: European Journal of Echocardiography - February 11, 2014 Category: Cardiology Authors: Bell, A., Rawlins, D., Bellsham-Revell, H., Miller, O., Razavi, R., Simpson, J. Tags: ORIGINAL ARTICLES Source Type: research

A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period
In conclusion, ventilation-induced preload variation principally affects the arterially determined isovolumic contraction period (AIC). Moreover, AIC can be determined solely from the arterial pressure waveform, whereas PEP also requires ECG measurement. Importantly, AIC determined from either the carotid or aortic pressure waveform are interchangeable, suggesting that, in contrast with PEP, AIC may be site independent.
Source: AJP: Heart and Circulatory Physiology - December 15, 2013 Category: Cardiology Authors: van Houwelingen, M. J., Merkus, D., Hofland, J., Bakker, J., Tenbrinck, R., te Lintel Hekkert, M., van Dijk, G., Hoeks, A. P. G., Duncker, D. J. Tags: CARDIAC EXCITATION AND CONTRACTION Source Type: research

Nitroxyl (HNO): A Novel Approach for the Acute Treatment of Heart Failure Original Articles
Conclusions— These data show the functional efficacy of a novel pure HNO donor to enhance myocardial function and present first-in-man evidence for its potential usefulness in HF. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifiers: NCT01096043, NCT01092325.
Source: Circulation: Heart Failure - November 19, 2013 Category: Cardiology Authors: Sabbah, H. N., Tocchetti, C. G., Wang, M., Daya, S., Gupta, R. C., Tunin, R. S., Mazhari, R., Takimoto, E., Paolocci, N., Cowart, D., Colucci, W. S., Kass, D. A. Tags: Contractile function, Congestive, Cardiovascular Pharmacology, Heart failure - basic studies Original Articles Source Type: research