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Specialty: Cardiology
Procedure: Anesthesia

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Total 200 results found since Jan 2013.

Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke
In this study, we tested the hypothesis that GLP-1 mediates neuroprotection induced by RIC and investigated the effect of GLP-1R activation on cerebral blood vessels, as a potential mechanism of GLP-1-induced protection against ischaemic stroke. A rat model of ischaemic stroke (90 min of  middle cerebral artery occlusion followed by 24-h reperfusion) was used. RIC was induced by 4 cycles of 5 min left hind limb ischaemia interleaved with 5-min reperfusion periods. RIC markedly (by ~ 80%) reduced the cerebral infarct size and improved the neurological score. The neuroprotection established by RIC was abolished by syst...
Source: Basic Research in Cardiology - May 3, 2021 Category: Cardiology Source Type: research

Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery: A Scientific Statement From the American Heart Association/American Stroke Association
Circulation. 2021 Apr 8:CIR0000000000000968. doi: 10.1161/CIR.0000000000000968. Online ahead of print.ABSTRACTPerioperative stroke is a potentially devastating complication in patients undergoing noncardiac, nonneurological surgery. This scientific statement summarizes established risk factors for perioperative stroke, preoperative and intraoperative strategies to mitigate the risk of stroke, suggestions for postoperative assessments, and treatment approaches for minimizing permanent neurological dysfunction in patients who experience a perioperative stroke. The first section focuses on preoperative optimization, including...
Source: Circulation - April 8, 2021 Category: Cardiology Authors: Curtis Benesch Laurent G Glance Colin P Derdeyn Lee A Fleisher Robert G Holloway Steven R Mess é Christina Mijalski M Timothy Nelson Martha Power Babu G Welch American Heart Association Stroke Council; Council on Arteriosclerosis, Thrombosis and Vascular Source Type: research

A comparison of two different management plans for patients requiring both carotid endarterectomy and coronary artery bypass grafting
CONCLUSIONS: For patients requiring CEA and CABG, performing both operations under general anaesthesia in the same session was safer than initially performing CEA under cervical block anaesthesia followed by CABG under general anaesthesia.PMID:33729273 | DOI:10.5830/CVJA-2020-042
Source: Cardiovascular Journal of Africa - March 17, 2021 Category: Cardiology Authors: Ata Niyazi Ecevit Okay Guven Karaca Mehmet Kalender Murat Bekmezci Mehmet Ali Sungur Osman Tansel Dar çın Source Type: research

Safety of Conscious Sedation for Transcatheter Aortic Valve Replacement Without an Anesthetist.
CONCLUSIONS: In this modest-sized transfemoral TAVR cohort with a low conversion rate to emergency surgery, TAVR-NA was associated with safety outcomes that were equivalent to TAVR-A. In healthcare systems where access to TAVR may be limited by anesthetic resources, TAVR-NA appears to be a reasonable option to enable the application of this therapy. PMID: 33542161 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - February 7, 2021 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Stroke During Hip Surgery.
Authors: Auer J, Primus C Abstract During hip replacement, acetabular and femur bone preparation may cause bone marrow extravasation. Paradoxical fat embolism occurs when emboli pass from the pulmonary to the systemic circulation by either a patent foramen ovale or pulmonary capillaries. Impaired consciousness in the immediate postoperative period of orthopedic surgery frequently results from hypovolemia, anemia, or residual anesthesia. A high index of suspicion is required to consider the possibility of paradoxical fat embolism. PMID: 33531447 [PubMed - in process]
Source: The Journal of Invasive Cardiology - February 5, 2021 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Impact of intraoperative neurologic deficits in carotid endarterectomy under regional anesthesia.
Conclusions. Neurologic deficits during carotid clamping are a predictor of perioperative stroke. Body mass index > 30 kg/m2, a lower degree of ipsilateral stenosis, and a higher degree of contralateral stenosis are independent predictors of neurologic deficits and, therefore, might play a role in the prevention of procedure-related stroke. PMID: 33487041 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - January 27, 2021 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits.
CONCLUSION: Increased ICP causes an increase in BP and CAVI, suggesting that enhanced stiffness of the muscular arteries contributes to high BP. Blocking the autonomic nervous system with hexamethonium suppresses the increase in BP and CAVI, indicating that these increases are mediated by activation of the autonomic nervous system. PMID: 33473056 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - January 23, 2021 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research