PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial

Conclusion: Multispecialty community practice enrollment into a large pragmatic trial of diagnostic testing strategies is both feasible and efficient. The PROMISE trial will compare the clinical effectiveness of an initial strategy of functional testing against an initial strategy of anatomical testing in symptomatic patients with suspected CAD. Quality of life, resource use, cost-effectiveness, and radiation exposure will be assessed.

Source: American Heart Journal - March 20, 2014 Category: Cardiology Authors: Pamela S. Douglas, Udo Hoffmann, Kerry L. Lee, Daniel B. Mark, Hussein R. Al-Khalidi, Kevin Anstrom, Rowena J. Dolor, Andrzej Kosinski, Mitchell W. Krucoff, Daniel W. Mudrick, Manesh R. Patel, Michael H. Picard, James E. Udelson, Eric J. Velazquez, Lawton Tags: Trial Design Source Type: research