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Specialty: Cardiology
Nutrition: Sodium

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Total 159 results found since Jan 2013.

Urinary Sodium and Potassium, and Risk of Ischaemic and Haemorrhagic Stroke (INTERSTROKE): a case-control study.
CONCLUSION: The association of sodium intake and stroke is J-shaped, with high sodium intake a stronger risk factor for intracerebral haemorrhage than ischemic stroke. Our data suggest that moderate sodium intake - rather than low sodium intake - combined with high potassium intake may be associated with the lowest risk of stroke and expected to be a more feasible combined dietary target. PMID: 33197265 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 17, 2020 Category: Cardiology Authors: Judge C, O'Donnell MJ, Hankey GJ, Rangarajan S, Chin SL, Rao-Melacini P, Ferguson J, Smyth A, Xavier D, Lisheng L, Zhang H, Lopez-Jaramillo P, Damasceno A, Langhorne P, Rosengren A, Dans AL, Elsayed A, Avezum A, Mondo C, Ryglewicz D, Czlonkowska A, Pogoso Tags: Am J Hypertens Source Type: research

Thoracic Aortic < sup > 18 < /sup > F-Sodium Fluoride Activity and Ischemic Stroke in Patients With Established Cardiovascular Disease
CONCLUSIONS: In patients with established cardiovascular disease, thoracic aortic 18F-sodium fluoride activity is associated with the progression of atherosclerosis and future ischemic stroke. Arterial 18F-sodium fluoride activity identifies localized areas of atherosclerotic disease activity that are directly linked to disease progression and downstream regional clinical atherothrombotic events. (DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury [DIAMOND], NCT02110303; Study Investigating the Effect of Drugs Used to Treat Osteoporosis on the Progression of Calcific Aortic Stenosis [SALTIRE II], NCT02132026; ...
Source: Atherosclerosis - February 20, 2022 Category: Cardiology Authors: Alexander J Fletcher Yong Y Tew Evangelos Tzolos Shruti S Joshi Jakub Kaczynski Jennifer Nash Samuel Debono Maria Lembo Jacek Kwiecinski Rong Bing Maaz B J Syed Mhairi K Doris Edwin J R van Beek Alistair J Moss William S Jenkins Niki L Walker Nikhil V Jos Source Type: research

Cost-effectiveness of a Household Salt Substitution Intervention: Findings From 20,995 Participants of the Salt Substitute and Stroke Study (SSaSS)
Conclusions: Replacing regular salt with salt substitute was a cost-saving intervention for the prevention of stroke and improvement of quality of life amongst the SSaSS participants.PMID:35311346 | DOI:10.1161/CIRCULATIONAHA.122.059573
Source: Circulation - March 21, 2022 Category: Cardiology Authors: Ka-Chun Li Liping Huang Maoyi Tian Gian Luca Di Tanna Jie Yu Xinyi Zhang Xuejun Yin Yishu Liu Zhixin Hao Bo Zhou Xiangxian Feng Zhifang Li Jianxin Zhang Jixin Sun Yuhong Zhang Yi Zhao Ruijuan Zhang Yan Yu Nicole Li Lijing L Yan Darwin R Labarthe Paul Elli Source Type: research

Development of Quality Indicators of Stroke Centers and Feasibility of Their Measurement Using a Nationwide Insurance Claims Database in Japan  - J-ASPECT Study.
CONCLUSIONS: We developed QIs for primary and comprehensive stroke care. The DPC database may allow efficient data collection at low cost and decreased burden to evaluate the developed QIs. PMID: 31554766 [PubMed - as supplied by publisher]
Source: Circulation Journal - September 25, 2019 Category: Cardiology Authors: Nishimura A, Nishimura K, Onozuka D, Matsuo R, Kada A, Kamitani S, Higashi T, Ogasawara K, Shimodozono M, Harada M, Hashimoto Y, Hirano T, Hoshino H, Itabashi R, Itoh Y, Iwama T, Kohriyama T, Matsumaru Y, Osato T, Sasaki M, Shiokawa Y, Shimizu H, Takekawa Tags: Circ J Source Type: research

The role of blood pressure management in stroke prevention: current status and future prospects
Expert Rev Cardiovasc Ther. 2022 Oct 16. doi: 10.1080/14779072.2022.2137490. Online ahead of print.ABSTRACTINTRODUCTION: Stroke is the second-leading cause of death worldwide and the second-leading cause of disability-adjusted life-years. It is well-known that hypertension is a significant risk factor for cardiovascular events, including stroke.AREAS COVERED: Recent interventional trials have demonstrated the superiority of intensive blood pressure (BP) control for prevention of cardiovascular events compared to standard BP control. Notably, in the Strategy of Blood Pressure Intervention in Elderly Hypertensive Patients (S...
Source: Expert Review of Cardiovascular Therapy - October 17, 2022 Category: Cardiology Authors: Keisuke Narita Satoshi Hoshide Kazuomi Kario Source Type: research

The Role of Combined SGLT1/SGLT2 Inhibition in Reducing the Incidence of Stroke and Myocardial Infarction in Patients with Type 2 Diabetes Mellitus
ConclusionsThe role of SGLT1/2 inhibition as an addition to GLP-1 RAs in patients with and without T2DM at increased risk for MI and stroke requires further study. Regardless, the finding that a relative increase in SGLT1/2 inhibition reduces the risk of MI and stroke as well as hospitalizations and urgent visits for heart failure could improve quality of life and reduce the healthcare burden associated with T2DM.
Source: Cardiovascular Drugs and Therapy - November 9, 2021 Category: Cardiology Source Type: research

Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Dipeptidyl Peptidase-4 Inhibitor on the Risks of New-Onset Atrial Fibrillation, Stroke and Mortality in Diabetic Patients: A Propensity Score-Matched Study in Hong Kong
ConclusionsBased on real-world data of type 2 diabetic patients in Hong Kong, SGLT2I use was associated with lower risk of incident AF, stroke/transient ischemic attack, and cardiovascular and all-cause mortality outcomes compared to DPP4I use.
Source: Cardiovascular Drugs and Therapy - February 10, 2022 Category: Cardiology Source Type: research

The Role of Combined SGLT1/SGLT2 Inhibition in Reducing the Incidence of Stroke and Myocardial Infarction in Patients with Type 2 Diabetes Mellitus
ConclusionsThe role of SGLT1/2 inhibition as an addition to GLP-1 RAs in patients with and without T2DM at increased risk for MI and stroke requires further study. Regardless, the finding that a relative increase in SGLT1/2 inhibition reduces the risk of MI and stroke as well as hospitalizations and urgent visits for heart failure could improve quality of life and reduce the healthcare burden associated with T2DM.
Source: Cardiovascular Drugs and Therapy - May 19, 2022 Category: Cardiology Source Type: research

Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Dipeptidyl Peptidase-4 Inhibitor on the Risks of New-Onset Atrial Fibrillation, Stroke and Mortality in Diabetic Patients: A Propensity Score-Matched Study in Hong Kong
ConclusionsBased on real-world data of type 2 diabetic patients in Hong Kong, SGLT2I use was associated with lower risk of incident AF, stroke/transient ischemic attack, and cardiovascular and all-cause mortality outcomes compared to DPP4I use.
Source: Cardiovascular Drugs and Therapy - May 29, 2023 Category: Cardiology Source Type: research

Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS)
Publication date: Available online 7 January 2020Source: American Heart JournalAuthor(s): Liping Huang, Maoyi Tian, Jie Yu, Qiang Li, Yishu Liu, Xuejun Yin, Jason HY Wu, Matti Marklund, Yangfeng Wu, Nicole Li, Paul Elliot, Lijing L. Yan, Darwin R. Labarthe, Zhixin Hao, Jingpu Shi, Xiangxian Feng, Jianxin Zhang, Yuhong Zhang, Ruijuan Zhang, Bo ZhouAbstractThe Salt Substitute and Stroke Study is an ongoing 5-year large-scale cluster randomized trial investigating the effects of potassium-enriched salt substitute compared to usual salt on the risk of stroke. The study involves 600 villages and 20,996 individuals in rural Chin...
Source: American Heart Journal - January 7, 2020 Category: Cardiology Source Type: research

Association of SGLT2 Inhibitors With Risk of Atrial Fibrillation and Stroke in Patients With and Without Type 2 Diabetes: A Systemic Review and Meta-Analysis of Randomized Controlled Trials
Abstract: Sodium-glucose cotransporter 2 (SGLT2) inhibitors have well-documented effects on reducing hospitalization for heart failure and cardiovascular mortality, although the effect on atrial fibrillation (AF) has not been comprehensively investigated. Therefore, we performed a meta-analysis to assess the association between SGLT2 inhibitors and AF risk by systematically searching PubMed, Embase, and ClinicalTrials.gov. Two investigators independently identified randomized controlled trials, which compared SGLT2 inhibitors with control in patients with type 2 diabetes, heart failure, or chronic kidney disease. Prima...
Source: Journal of Cardiovascular Pharmacology - February 1, 2022 Category: Cardiology Tags: Review Article Source Type: research

Hyponatremia Is Associated With Increased The Mortality In Patients With Acute Stroke: A Systematic Review And Meta-Analysis
Background and Aims: Hyponatremia is a common electrolyte abnormality which is associated with increased mortality both in hospitalized patients and in the community. Low serum sodium levels are frequently found in patients with acute stroke and could adversely affect their prognosis. We aimed to assess available data regarding the mortality risk associated with hypontatremia in patients with acute stroke
Source: Atherosclerosis - August 2, 2019 Category: Cardiology Authors: F. Barkas, E. Klouras, A. Liontos, E. Megapanou, G. Liamis, H. Milionis Tags: E-poster session Source Type: research

Sodium-glucose transport protein 2 inhibitors and risk of incident stroke: A systematic review and meta-analysis
Background and Aims: Although experimental studies have suggested a potential neuroprotective effect of sodium-glucose contransporter-2 (SGLT2) inhibitors, human trials have demonstrated controversial results regarding their effect on the risk of stroke. In this context, we evaluated published evidence regarding the effect of treatment with SGLT2 inhibitors on the risk of ischemic stroke.
Source: Atherosclerosis - December 1, 2020 Category: Cardiology Authors: F. Barkas, E. Liberopoulos, S. Filippas Ntekouan, H. Milionis Source Type: research