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Specialty: Cardiology
Condition: Cardiogenic Shock

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Total 235 results found since Jan 2013.

GDF ‐15 at admission predicts cardiovascular death, heart failure, and bleeding outcomes in patients with CAD
ConclusionsIn patients with CAD, admission levels of GDF-15 were associated with an increased 1  year risk of CV death, HF, and bleeding outcomes, but not with thrombotic events. GDF-15 may be a prognostic biomarker for CV death, HF, and bleeding outcomes and could be used to refine the risk assessment of these specific clinical outcomes.Trial Registration:ClinicalTrials.gov Identifier: NCT04044066
Source: ESC Heart Failure - August 25, 2023 Category: Cardiology Authors: Jiali Wang, Tao Zhang, Feng Xu, Wei Gao, Ming Chen, Huadong Zhu, Jun Xu, Xinxin Yin, Jiaojiao Pang, Song Zhang, Mengke Wei, Jiahao Chen, Ying Liu, Xuezhong Yu, Derek P. Chew, Yuguo Chen Tags: Original Article Source Type: research

Effect of Concomitant Cardiac Arrest on Outcomes in Patients With Acute Coronary Syndrome-Related Cardiogenic Shock
Patients with acute coronary syndrome (ACS)-related cardiogenic shock (CS) with or without concomitant CA may have disparate prognoses. We compared clinical characteristics and outcomes of patients with CS secondary to ACS with and without cardiac arrest (CA). Between 2014 and 2020, 1,573 patients with ACS-related CS with or without CA who underwent percutaneous coronary intervention enrolled in a multicenter Australian registry were analyzed. Primary outcome was 30-day major adverse cardiovascular and cerebrovascular events (MACCE) (composite of mortality, myocardial infarction, stent thrombosis, target vessel revascularization and stroke).
Source: The American Journal of Cardiology - August 2, 2023 Category: Cardiology Authors: Wayne C. Zheng, Diem Dinh, Samer Noaman, Jason E. Bloom, Riley J. Batchelor, Jeffrey Lefkovits, Angela L. Brennan, Christopher M. Reid, Omar Al-Mukhtar, James A. Shaw, Dion Stub, Yang Yang, Craig French, David M. Kaye, Nicholas Cox, William Chan Source Type: research

Acute coronary syndrome in very elderly patients —a real-world experience
AbstractVery elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes (ACS). Notably, age represents both a proxy of frailty and an exclusion criterion in clinical randomized trials, which probably contributes to lack of data and undertreatment of real-world elderly patients. The aim of the study is to describe patterns of treatment and outcome of very elderly patients with ACS. All consecutive patients aged  ≥ 80 years old (yo) admitted between January 2017 and December 2019 with ACS were included. The primary endpoint was in-hospital occurrence of major adv...
Source: Heart and Vessels - July 15, 2023 Category: Cardiology Source Type: research

A Novel Speckle-Tracking Echocardiographic Parameter Assessing Left Ventricular Loading During VA ECMO in a Pre-clinical Model of Cardiogenic Shock
Left ventricular (LV) stroke work index (SWI) and cardiac power index (CPI) are considered load-independent parameters and can yield better prognostic values than LV ejection fraction (EF) in cardiogenic shock. However, accurate measurement of these parameters using Pressure-Volume catheters (PVC) is too invasive for routine clinical use. The aim of this study was to investigate whether Pressure-Strain Product (PSP), a novel Speckle-Tracking echocardiography (STE) parameter, can non-invasively predict PVC-based LV SWI and CPI in an ovine model of cardiogenic shock undergoing peripheral VA ECMO.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: K. Sato, S. Heinsar, N. Obonyo, K. Wildi, K. Liu, S. Farah, C. Ainola, N. Sato, S. Ijuin, S. Kyun Ro, G. Fior, L. Gandini, M. Bouquet, E. Wilson, M. Passmore, K. Hyslop, J. Chan, D. Platts, G. Scalia, J. Suen, G. Li Bassi, J. Fraser Source Type: research

Improved mortality and haemodynamics with milrinone in cardiogenic shock due to acute decompensated heart failure
ConclusionsThe use of milrinone compared with dobutamine in patients with ADHF-CS is associated with lower 30  day mortality and improved haemodynamics. These findings warrant further study in future randomized controlled trials.
Source: ESC Heart Failure - June 16, 2023 Category: Cardiology Authors: Eduard Rodenas ‐Alesina, Fernando Luis Scolari, Vicki N. Wang, Darshan H. Brahmbhatt, Vesna Mihajlovic, Nicole L. Fung, Madison Otsuki, Filio Billia, Christopher B. Overgaard, Adriana Luk Tags: Original Article Source Type: research

Rescue aortic valvuloplasty for severe aortic stenosis is simple and effective in severely hemodynamically compromised patients presenting to centers without on-site heart surgery or TAVI facilities
AbstractManagement of high-risk patients with severe aortic stenosis (AS) is a challenging issue. The prognosis of patients with AS presenting  with therapy-refractory pulmonary edema (RPE) or cardiogenic shock (CS) remains poor. The purpose of this study was to assess the 30-day mortality of rescue percutaneous balloon aortic valvuloplasty (PBAV) in AS patients presenting with RPE or CS in a community-based hospital without on- site heart surgery. From January 2016 to February 2019, we identified consecutively admitted patients with CS or RPE related to severe AS who underwent emergent PBAV. The primary end...
Source: Heart and Vessels - May 30, 2023 Category: Cardiology Source Type: research

Transcatheter Aortic Valve Replacement for Aortic Valve Infective Endocarditis: A Systematic Review and Call for Action
AbstractWe aimed to systematically analyze the literature on the use of transcatheter aortic valve replacement (TAVR) to treat active aortic valve infective endocarditis (AV-IE). Surgery is declined in one-third of patients with IE who meet indications because of prohibitive surgical risk. TAVR might be an alternative for selected patients with AV-IE as a bridge-to-surgery or stand-alone therapy. PubMed/MEDLINE, Embase, and Cochrane databases were searched (2002 –2022) for studies on TAVR use in active AV-IE. Of 450 identified reports, six met inclusion criteria (all men, mean age 71 ± 12 years, median Society of T...
Source: Cardiology and Therapy - April 20, 2023 Category: Cardiology Source Type: research

A Small Increase in Serum Creatinine within 48  h of Hospital Admission Is an Independent Predictor of In-Hospital Adverse Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Findings from the Improving Care for Cardiovascular Disease in the China Project
CONCLUSION: A small increase in Scr during hospitalization in patients with STEMI undergoing primary PCI that does not meet the criteria for AKI is a risk factor for in-hospital adverse outcomes. This effect is maintained in patients with normal Scr at hospitalization. Trial Registration. Clinical trial registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT02306616.PMID:37025394 | PMC:PMC10072956 | DOI:10.1155/2023/1374206
Source: Cardiology Research and Practice - April 7, 2023 Category: Cardiology Authors: Jiajia Zhu Wenxian Liu Jiang Li Changsheng Ma Dong Zhao Source Type: research

Clinical Efficacy and Safety of Early Intravenous Administration of Beta-Blockers in Patients Suffering from Acute ST-Segment Elevation Myocardial Infarction Without Heart Failure Undergoing Primary Percutaneous Coronary Intervention: A Study-Level Meta-Analysis of Randomized Clinical Trials
ConclusionIntravenous beta-blockers improved the MSI, decreased the risk of VT/VF in the first 24 h, and were associated with increased LVEF at 1 week and 6 months following PCI. In particular, intravenous beta-blockers started before PCI is beneficial for patients with LAD lesions.
Source: Cardiovascular Drugs and Therapy - April 1, 2023 Category: Cardiology Source Type: research

Acute coronary syndrome in very elderly patients —a real-world experience
AbstractVery elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes (ACS). Notably, age represents both a proxy of frailty and an exclusion criterion in clinical randomized trials, which probably contributes to lack of data and undertreatment of real-world elderly patients. The aim of the study is to describe patterns of treatment and outcome of very elderly patients with ACS. All consecutive patients aged  ≥ 80 years old (yo) admitted between January 2017 and December 2019 with ACS were included. The primary endpoint was in-hospital occurrence of major adv...
Source: Heart and Vessels - March 28, 2023 Category: Cardiology Source Type: research