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Specialty: Cardiology
Condition: Aortic Aneurysm
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Total 129 results found since Jan 2013.
MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice Stroke
Conclusions
MKEY injection protects against stroke-induced brain injury, probably by inhibiting MoM-mediated neuroinflammation.
Source: JAHA:Journal of the American Heart Association - September 14, 2016 Category: Cardiology Authors: Fan, Y., Xiong, X., Zhang, Y., Yan, D., Jian, Z., Xu, B., Zhao, H. Tags: Ischemic Stroke, Neuroprotectants Source Type: research
Reduced bile acid excretion is an independent risk factor for stroke and mortality: A prospective follow-up study
This study investigated the association of bile acid excretion (BAE) with stroke incidence and mortality.
Source: Atherosclerosis - December 13, 2019 Category: Cardiology Authors: Gideon Charach, Eli Karniel, Ilya Novikov, Leonid Galin, Shely Vons, Itamar Grosskopf, Lior Charach Source Type: research
This Week in Cardiology: Advances in Stroke, Heart Medicine
(MedPage Today) -- Two installments of Hot Topics will feature predictions about the big developments expected in stroke and cardiovascular medicine. And guidelines will be in the headlines again, this time for abdominal aortic aneurysm.
Source: MedPage Today Cardiovascular - January 27, 2014 Category: Cardiology Source Type: news
Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF
Conclusion
Patients with PAD in ROCKET AF did not have a statistically significant higher risk of stroke or systemic embolism than patients without PAD, and there were similar efficacy outcomes in patients treated with rivaroxaban and warfarin. In PAD patients, there was a higher risk of major bleeding or NMCR bleeding with rivaroxaban when compared with warfarin (interaction P = 0.037). Further investigation is warranted to validate this subgroup analysis and determine the optimal treatment in this high-risk cohort of AF patients with PAD.
Source: European Heart Journal - January 21, 2014 Category: Cardiology Authors: Jones, W. S., Hellkamp, A. S., Halperin, J., Piccini, J. P., Breithardt, G., Singer, D. E., Fox, K. A. A., Hankey, G. J., Mahaffey, K. W., Califf, R. M., Patel, M. R. Tags: Atrial fibrillation Source Type: research
Elective ascending aortic aneurysm repair outcomes in a nationwide US cohort
Conclusions
The overall rate of in-hospital death, stroke and MI is nearly 5% in patients undergoing elective ascending aortic aneurysm repair. Among several predictors, chronic weight loss is associated with the largest increase in the risk of poor outcomes. Higher hospital volume is associated with a lower in-hospital mortality, highlighting the importance to refer patients to high-volume centres while discussing the risks and benefits of proceeding with repair.
Source: Heart - June 26, 2023 Category: Cardiology Authors: Beyer, S. E., Secemsky, E. A., Khabbaz, K., Carroll, B. J. Tags: Aortic and vascular disease Source Type: research
1990-2010 Global Cardiovascular Disease Atlas
Worldwide, the cardiovascular diseases (CVDs) contributing most to the total global burden of disease in 2010 were ischemic heart disease (5.2% of all disability-adjusted life years [DALYs] lost) and stroke (4.1% of all DALYs). The other major CVDs were hypertensive heart disease, cardiomyopathies, rheumatic heart disease, atrial fibrillation, aortic aneurysm, peripheral vascular disease, and endocarditis. The highest per capita CVD burden fell upon the Eastern Europe and Central Asia regions (). In the large populations of the South Asia and North Africa and Middle East regions, the absolute burden of CVDs is high and mor...
Source: CVD Prevention and Control - March 1, 2014 Category: Cardiology Authors: Andrew E. Moran, Gregory A. Roth, Jagat Narula, George A. Mensah Tags: Atlas Source Type: research
How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People.
CONCLUSIONS: -The majority of initial presentations of CVD are neither MI nor ischemic stroke, yet most primary prevention studies focus on these presentations. Sex has differing associations with different CVDs, with implications for risk prediction and management strategies. Clinical Trial Registration Information-www.clinicaltrials.gov. Identifier: NCT01164371.
PMID: 26330414 [PubMed - as supplied by publisher]
Source: Circulation - September 1, 2015 Category: Cardiology Authors: George J, Rapsomaniki E, Pujades-Rodriguez M, Shah AD, Denaxas S, Herrett E, Smeeth L, Timmis A, Hemingway H Tags: Circulation Source Type: research
The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis
CONCLUSION: This MR study suggested a causal relationship between Lp(a) and CHD, AA, and ISL, but not associated with AF, HF, IS, LIS, ISS, HBP, or PE. Our work further verifies the association between Lp(a) and various CVD, resulting in improved Lp(a) management and a reduction in the prevalence of CVD.PMID:36303257 | DOI:10.1186/s40001-022-00825-6
Source: Atherosclerosis - October 28, 2022 Category: Cardiology Authors: Shiyue Wang Li Zha Jian Chen Dongjie Du Danyang Liu Ming Zhong Rongfang Shang Dongxue Sun Chang Sun Enze Jin Source Type: research
Heterogeneous impact of classic atherosclerotic risk factors on different arterial territories: the EPIC-Norfolk prospective population study
Conclusion
The heterogeneity in the risk factor–CVD associations supports the concept of pathophysiological differences between atherosclerotic CVD manifestations and could have implications for CVD prevention.
Source: European Heart Journal - March 14, 2016 Category: Cardiology Authors: Stoekenbroek, R. M., Boekholdt, S. M., Luben, R., Hovingh, G. K., Zwinderman, A. H., Wareham, N. J., Khaw, K.-T., Peters, R. J. G. Tags: Prevention and epidemiology Source Type: research
Aortic Arch Reconstructive Surgery with Conventional Techniques versus Frozen Elephant Trunk: A Systematic Review and Meta-Analysis
Conclusion Current evidence suggests that FET surgery is associated with lower mortality in patients with thoracic aneurysmal disease and dissections, without a significant increase in stroke, bleeding or operative times. However, the risk of spinal cord ischemia is increased in FET patients. A well powered randomized trial is needed to evaluate this evolving field. Teaser To our knowledge, we have performed the most detailed meta-analysis for the use of Frozen Elephant Trunk (FET) surgery, yielding a systematic review with the most number of patients studied. Our systematic review and meta-analysis uses the most up to dat...
Source: Canadian Journal of Cardiology - December 26, 2017 Category: Cardiology Source Type: research
Aortic Arch Reconstructive Surgery With Conventional Techniques vs Frozen Elephant Trunk: A Systematic Review and Meta-Analysis
Conclusions Current evidence suggests that FET surgery is associated with lower mortality in patients with thoracic aneurysmal disease and dissections, without a significant increase in stroke, bleeding, or operative times. However, the risk of spinal cord ischemia is increased in patients who undergo FET. A well-powered randomized trial is needed to evaluate this evolving field.
Source: Canadian Journal of Cardiology - February 21, 2018 Category: Cardiology Source Type: research
Self-Reported Eczema in Relation with Mortality from Cardiovascular Disease in Japanese: the Japan Collaborative Cohort Study.
CONCLUSIONS: Self-reported frequent eczema was associated with increased risk of mortality from CHD, but not other major CVD, in a Japanese general population. Since steroid usage was not considered, future studies should include it as a potential confounding factor.
PMID: 30700678 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 1, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
The importance of and current trends in the endovascular program – A single center experience
Conclusion In the AAA group, the percentage of EVAR stabilized during the last 5 years at about 32% of the total number of treated patients. Given the excellent results of open carotid surgery and the unconvincing results of stenting trials, we consider open carotid surgery to be better than carotid artery primary stenting.
Source: Cor et Vasa - April 13, 2015 Category: Cardiology Source Type: research
