Stroke RSS Page 15

Filtered By:
Specialty: Biomedical Science

This page shows you your search results in order of date. This is page number 15.

Order by Relevance | Date

Total 2301 results found since Jan 2013.

Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity
Despite advances in acute care, ischemic stroke remains a major cause of long-term disability. Approaches targeting both neuronal and glial responses are needed to enhance recovery and improve long-term outcome. The complement C3a receptor (C3aR) is a regulator of inflammation with roles in neurodevelopment, neural plasticity, and neurodegeneration. Using mice lacking C3aR (C3aR–/–) and mice overexpressing C3a in the brain, we uncovered 2 opposing effects of C3aR signaling on functional recovery after ischemic stroke: inhibition in the acute phase and facilitation in the later phase. Peri-infarct astrocyte reactivity w...
Source: Journal of Clinical Investigation - May 15, 2023 Category: Biomedical Science Authors: Anna Stokowska, Markus Aswendt, Daniel Zucha, Stephanie Lohmann, Frederique Wieters, Javier Morán Suarez, Alison L. Atkins, YiXian Li, Maria Miteva, Julia Lewin, Dirk Wiedermann, Michael Diedenhofen, Åsa Torinsson Naluai, Pavel Abaffy, Lukas Valihrach, Source Type: research

Vascular endothelial growth factor receptor 1 gene ( < em > FLT1 < /em > ) longevity variant increases lifespan by reducing mortality risk posed by hypertension
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.PMID:37178326 | DOI:10.18632/aging.204722
Source: Aging - May 13, 2023 Category: Biomedical Science Authors: Brian J Morris Randi Chen Timothy A Donlon Kalpana J Kallianpur Kamal H Masaki Bradley J Willcox Source Type: research

The effect of foot-stretcher position and stroke rate on ergometer rowing kinematics
This study aimed to determine the effects of altering the foot-stretcher position on rowing kinematics across different stroke rates. Eleven college-level rowers took part in this study. A rowing ergometer was modified to allow the height and angle of the foot-stretcher to be adjusted. Seven foot-stretcher positions were tested, each at rates of 22, 26, and 32 strokes per minute. Sagittal plane kinematic waveforms were com pared between conditions for all major joints using statistical parametric mapping, and temporal variables were assessed (p
Source: PLoS One - May 11, 2023 Category: Biomedical Science Authors: Ian Engstrom Source Type: research

Influences of age and gender on operative risks following carotid endarterectomy: A systematic review and meta-analysis
by Sothida Nantakool, Busaba Chuatrakoon, Saritphat Orrapin, Rachel Leung, Dominic P. J. Howard, Amaraporn Rerkasem, Jos é G. B. Derraik, Kittipan Rerkasem ObjectivesThis review aims to undertake a comprehensive review of the literature and investigate associations of age and gender on 30 days post carotid endarterectomy (CEA) and up to 5 years post CEA stroke, death, and combined stroke and death. DesignA systematic review and meta-analysis. MethodsThree main electronic databases including the Cochrane Library, MEDLINE, and Embase were searched from their inception to July 2022. Studies examining operative risks (i.e., s...
Source: PLoS One - May 10, 2023 Category: Biomedical Science Authors: Sothida Nantakool Source Type: research

Effects of myocardial sheetlet sliding on left ventricular function
Biomech Model Mechanobiol. 2023 May 6. doi: 10.1007/s10237-023-01721-6. Online ahead of print.ABSTRACTLeft ventricle myocardium has a complex micro-architecture, which was revealed to consist of myocyte bundles arranged in a series of laminar sheetlets. Recent imaging studies demonstrated that these sheetlets re-orientated and likely slided over each other during the deformations between systole and diastole, and that sheetlet dynamics were altered during cardiomyopathy. However, the biomechanical effect of sheetlet sliding is not well-understood, which is the focus here. We conducted finite element simulations of the left...
Source: Biomechanics and Modeling in Mechanobiology - May 6, 2023 Category: Biomedical Science Authors: Yu Zheng Wei Xuan Chan Sonia Nielles-Vallespin Andrew D Scott Pedro F Ferreira Hwa Liang Leo Choon Hwai Yap Source Type: research

Effect of alteplase, benzodiazepines and beta-blocker on post-stroke pneumonia: Exploration of VISTA-Acute
by Thanh G. Phan, Richard Beare, Philip M. Bath, Svitlana Ievlieva, Stella Ho, John Ly, Amanda G. Thrift, Velandai K. Srikanth, Henry Ma, on behalf of the VISTA-Acute Collaborators BackgroundPost-stroke pneumonia is a frequent complication of stroke and is associated with high mortality. Investigators have described its associations with beta-blocker. However, there has been no evaluation of the role of recombinant tissue plasminogen activator (RTPA). We postulate that RTPA may modify the effect of stroke on pneumonia by reducing stroke disability. We explore this using data from neuroprotection trials in Virtual Internati...
Source: PLoS One - May 1, 2023 Category: Biomedical Science Authors: Thanh G. Phan Source Type: research

Leukocyte Telomere Length and Lacunar Stroke: A Mendelian Randomization Study
Biomed Environ Sci. 2023 Apr 20;36(4):367-370. doi: 10.3967/bes2023.042.NO ABSTRACTPMID:37105911 | DOI:10.3967/bes2023.042
Source: Biomedical and Environmental Sciences : BES - April 27, 2023 Category: Biomedical Science Authors: Mei Juan Dang Tao Li Li Li Zhao Ye Li Xiao Ya Wang Yu Lun Wu Jia Liang Lu Zi Wei Lu Yang Yang Yu Xuan Feng He Ying Wang Ya Ting Jian Song Hua Fan Yu Jiang Gui Lian Zhang Source Type: research

Lower Baseline LDL Cholesterol Affects All-cause Mortality in Patients with First Percutaneous Coronary Intervention
CONCLUSION: In this study, a high baseline LDL-C was not associated with a low risk of clinical outcomes in CAD patients undergoing first PCI, which suggested that the "cholesterol paradox" may be inapplicable to Chinese populations.PMID:37105907 | DOI:10.3967/bes2023.038
Source: Biomedical and Environmental Sciences : BES - April 27, 2023 Category: Biomedical Science Authors: Xi Chen Hao Chen Bo Lu Wei Min Zhang Yuan Tao Qing Cheng Wang Guo Sheng Fu Wen Bin Zhang Source Type: research

Effect of Age and Sex on Stroke Mortality of Young and Middle-aged Adults in China, 2002-2019, and Predictions to 2030
CONCLUSION: Significant sex and age disparities in the trends of stroke mortality among young and middle-aged adults were identified in China. Targeted health policy measures are needed to address the burden of stroke in the young generation, especially for rural men, with a focus on the prevention and management of high risk factors.PMID:37105905 | DOI:10.3967/bes2023.036
Source: Biomedical and Environmental Sciences : BES - April 27, 2023 Category: Biomedical Science Authors: Yi Zhai Xiang Si Wen Zhi Wang Wen Hua Zhao Source Type: research

Pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20