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Total 2301 results found since Jan 2013.

A Nested Case-Control Study to Explore the Association between Immunoglobulin G N-glycans and Ischemic Stroke
CONCLUSION: This study validated that altered IgG N-glycan traits were associated with incident IS in men, suggesting that sex discrepancies might exist in these associations.PMID:37253665 | DOI:10.3967/bes2023.048
Source: Biomedical and Environmental Sciences : BES - May 30, 2023 Category: Biomedical Science Authors: Bi Yan Wang Man Shu Song Jie Zhang Xiao Ni Meng Wei Jia Xing You Xin Wang Source Type: research

Improvement of predictive accuracies of functional outcomes after subacute stroke inpatient rehabilitation by machine learning models
ConclusionsThis study suggested that the machine learning models outperformed SLR for predicting FIM prognosis. The machine learning models used only patients ’ background characteristics and FIM scores at admission and more accurately predicted FIM gain than previous studies. ANN, SVR, and GPR outperformed RT and EL. GPR could have the best predictive accuracy for FIM prognosis.
Source: PLoS One - May 26, 2023 Category: Biomedical Science Authors: Yuta Miyazaki Source Type: research

Sociodemographic disparities in concomitant left atrial appendage occlusion during cardiac valve operations
by Ayesha P. Ng, Nikhil Chervu, Yas Sanaiha, Amulya Vadlakonda, Elsa Kronen, Peyman Benharash BackgroundSociodemographic disparities in atrial fibrillation (AF) management and thromboembolic prophylaxis have previously been reported, which may involve inequitable access to left atrial appendage occlusion (LAAO) during cardiac surgery. The present study aimed to evaluate the association of LAAO utilization with sex, race, and hospital region among patients with AF undergoing heart valve operations. MethodsAdults with AF undergoing valve replacement/repair in the 2012 –2019 National Inpatient Sample were identified and str...
Source: PLoS One - May 25, 2023 Category: Biomedical Science Authors: Ayesha P. Ng Source Type: research

Plasma exosome proteomics reveals the pathogenesis mechanism of post-stroke cognitive impairment
Aging (Albany NY). 2023 May 20;15. doi: 10.18632/aging.204738. Online ahead of print.ABSTRACTExploration and utilization of exosome biomarkers and their related functions provide the possibility for the diagnosis and treatment of post-stroke cognitive impairment (PSCI). To identify the new diagnostic and prognostic biomarkers of plasma exosome were uzed label-free quantitative proteomics and biological information analysis in PSCI patients. Behavioral assessments were performed, including the Mini-Mental Status Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Barthel index, the Morse Fall Seale (MFS) betwe...
Source: Aging - May 21, 2023 Category: Biomedical Science Authors: Baoyun Qi Lingbo Kong Xinxing Lai Linshuang Wang Fei Liu Weiwei Ji Dongfeng Wei Source Type: research

Role of cardiovascular magnetic resonance imaging and cardiopulmonary exercise test in predicting composite clinical outcomes in patients with hypertrophic cardiomyopathy
by Ji-won Hwang, Sang-Chol Lee, Darae Kim, Jihoon Kim, Eun Kyoung Kim, Sung-A. Chang, Sung-Ji Park, Sung Mok Kim, Yeon Hyeon Choe, Seung Woo Park We aimed to evaluate the additive value of cardiovascular magnetic resonance imaging (CMR) and cardiopulmonary exercise test (CPET) to predict clinical outcomes in patients with HCM. We enrolled 373 patients with HCM and normal left ventricular systolic function who underwent CPET and CMR. The pri mary outcome was a clinical composite of all-cause death, cardiac transplantation, stroke, heart failure requiring hospitalization and defibrillator implantation. During a follow-up of...
Source: PLoS One - May 16, 2023 Category: Biomedical Science Authors: Ji-won Hwang Source Type: research