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Specialty: Cancer & Oncology
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Total 1099 results found since Jan 2013.
RNA splicing: a dual-edged sword for hepatocellular carcinoma
AbstractRNA splicing is the fundamental process that brings diversity at the transcriptome and proteome levels. The spliceosome complex regulates minor and major processes of RNA splicing. Aberrant regulation is often associated with different diseases, including diabetes, stroke, hypertension, and cancer. In the majority of cancers, dysregulated alternative RNA splicing (ARS) events directly affect tumor progression, invasiveness, and often lead to poor survival of the patients. Alike the rest of the gastrointestinal malignancies, in hepatocellular carcinoma (HCC), which alone contributes to ~ 75% of the liver cancer...
Source: Medical Oncology - August 16, 2022 Category: Cancer & Oncology Source Type: research
Impact of the state of emergency on trends in the care of three major diseases at Showa University Hospital, Japan: a retrospective and descriptive study
CONCLUSIONS: This study showed a long-term decrease in cancer patient visits to Showa University Hospital since the beginning of the COVID-19 pandemic compared to the previous 3 years. It is also possible that medical care that would have been available may not have been provided due to the state of emergency, so it is necessary to follow up patients while keeping a close eye on measures other than infectious diseases.PMID:35968063 | PMC:PMC9351415 | DOI:10.15167/2421-4248/jpmh2022.63.2.2210
Source: Cancer Control - August 15, 2022 Category: Cancer & Oncology Authors: Akira Minoura Kouzou Murakami Masaaki Matoba Yoshinori Ito Yumi Kamijo Akatsuki Kokaze Source Type: research
Short bevacizumab infusion as an effective and safe treatment for colorectal cancer
Mol Clin Oncol. 2022 Jul 27;17(3):139. doi: 10.3892/mco.2022.2572. eCollection 2022 Sep.ABSTRACTBevacizumab is a humanized monoclonal antibody that contains <10% murine protein. To prevent infusion-related hypersensitivity reactions (HSRs), the initial bevacizumab infusion is delivered for 90 min, the second for 60 min and subsequent doses for 30 min. Several previous studies have shown that short bevacizumab infusions are safe and do not result in severe HSRs in patients with colorectal, lung, ovarian and brain cancer. However, the efficacy of short bevacizumab infusions for colorectal cancer management remains unclear...
Source: Clinical Colorectal Cancer - August 11, 2022 Category: Cancer & Oncology Authors: Koichi Taira Shunsuke Okazaki Kohei Akiyoshi Hirohisa Machida Tetsuro Ikeya Akie Kimura Akinobu Nakata Yuji Nadatani Masaki Ohminami Shusei Fukunaga Koji Otani Shuhei Hosomi Fumio Tanaka Noriko Kamata Yasuaki Nagami Yasuhiro Fujiwara Source Type: research
Linear Low-Intensity Extracorporeal Shockwave Therapy as a Method for Penile Rehabilitation in Erectile Dysfunction Patients after Radical Prostatectomy: A Randomized, Single-Blinded, Sham-Controlled Clinical Trial
CONCLUSIONS: LI-LiESWT using the LSTC-ED® technique is a suitable and safe method for penile rehabilitation in patients with ED after bilateral NS RP, not only because of the vasculogenic effect of LI-LiESWT but also because of its neuroprotective and/or regenerative effects.PMID:35947945 | DOI:10.1159/000525973
Source: Cancer Control - August 10, 2022 Category: Cancer & Oncology Authors: Igor Motil Daniel Macik Katerina Sramkova Jiri Jarkovsky Tatjana Sramkova Source Type: research
The Effect of Chronic Disease Management Program on the Risk of Complications in Patients With Hypertension in Korea
CONCLUSION: The results showed that participants of the chronic disease management program were less likely to have hypertension complications compared to non-participants. Enhancing the participation rate may be related to better outcomes and reducing medical expenses among patients with chronic diseases.PMID:35942556 | DOI:10.3346/jkms.2022.37.e243
Source: Cancer Control - August 9, 2022 Category: Cancer & Oncology Authors: Sang Ah Lee Hyeki Park Woorim Kim Sun Ok Song Hyunsun Lim Sung-Youn Chun Source Type: research
Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study
Lancet Public Health. 2022 Aug 1:S2468-2667(22)00110-4. doi: 10.1016/S2468-2667(22)00110-4. Online ahead of print.ABSTRACTBACKGROUND: The improvement of life expectancy is one of the aims of the Healthy China 2030 blueprint. We aimed to investigate the extent to which healthy lifestyles are associated with life expectancy in Chinese adults.METHODS: We used the prospective China Kadoorie Biobank (CKB) study to examine the relative risk of mortality associated with individual and combined lifestyle factors (never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, an...
Source: Cancer Control - August 4, 2022 Category: Cancer & Oncology Authors: Qiufen Sun Dongmei Yu Junning Fan Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Xiaoming Yang Sam Sansome Yongming Wang Wenhua Zhao Junshi Chen Zhengming Chen Liyun Zhao Jun Lv Liming Li China Kadoorie Biobank Collaborative Group Source Type: research
Targeted Therapy for Kidney Cancer Linked to Higher Cardiac Risk Targeted Therapy for Kidney Cancer Linked to Higher Cardiac Risk
Patients on targeted therapy were more likely to develop conditions such as heart attacks and stroke than were those who took cytokine therapy.MDedge News
Source: Medscape Hematology-Oncology Headlines - August 3, 2022 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Impact of cancer diagnosis on distribution and trends of cardiovascular hospitalizations in the USA between 2004 to 2017
CONCLUSIONS: In contrast to declining trends in patients without cancer, primary cardiovascular admissions in patients with cancer is increasing. The highest admission rates are in patients with hematological cancer and the most common cause of admission is heart failure.PMID:35913736 | DOI:10.1093/ehjqcco/qcac045
Source: Clinical Lung Cancer - August 1, 2022 Category: Cancer & Oncology Authors: Ofer Kobo Zahra Raisi-Estabragh Sofie Gevaert Jamal S Rana Harriette G C Van Spall Ariel Roguin Steffen E Petersen Bonnie Ky Mamas A Mamas Source Type: research
ADT Use for Prostate Cancer Linked to Increased Risk for CVD Death
Risk increased for CVD death and for death from ischemic heart disease and stroke, especially among those aged 70 to 79 years
Source: The Doctors Lounge - Oncology - July 29, 2022 Category: Cancer & Oncology Tags: Cardiology, Internal Medicine, Oncology, Pharmacy, Urology, Geriatrics, Journal, Source Type: news
In Patients with Acute Ischemic Stroke and Cancer: The Shorter Interval, the Higher D-Dimer
CONCLUSION: In conclusion, in patients with ischemic stroke and cancer, patients with short interval time between the diagnosis of ischemic stroke and cancer had higher D-dimer than patients with long interval time.PMID:35901344 | DOI:10.31557/APJCP.2022.23.7.2375
Source: Asian Pacific Journal of Cancer Prevention - July 28, 2022 Category: Cancer & Oncology Authors: Xin-Kun Wang Min-Hang Zhou Source Type: research
