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Specialty: Cancer & Oncology
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Total 1099 results found since Jan 2013.
Risk of mortality and other adverse outcomes from myocardial infarction in cancer survivors: a meta-analysis
ConclusionThis meta-analysis shows that cancer increases the risk of all-cause mortality, recurrent MI, and major bleeding in MI patients but is not associated with the risk of cardiovascular death. Therefore, comprehensive multidisciplinary management and monitoring of potential future adverse events in MI patients with cancer are needed.Systematic review registrationThe meta-analysis was registered in the International Register of Prospective Systematic Reviews (NO. CRD42022332775).
Source: International Journal of Clinical Oncology - November 28, 2022 Category: Cancer & Oncology Source Type: research
Risk of venous thromboembolism among women receiving ospemifene: a comparative observational study
Conclusion: This real-world safety analysis found no increase in risk of VTE or other adverse events with use of ospemifene in postmenopausal women.PMID:36420373 | PMC:PMC9677319 | DOI:10.1177/20420986221135931
Source: Cancer Control - November 24, 2022 Category: Cancer & Oncology Authors: Beth L Nordstrom Bin Cai Fabio De Gregorio Lu Ban Kathy H Fraeman Yuki Yoshida Trevor Gibbs Source Type: research
Poorly Differentiated Lung Cancer with Intracardiac Extension Causing Malignant Stroke in a Peritoneal Dialysis Patient: a Case Report
SN Compr Clin Med. 2022;4(1):255. doi: 10.1007/s42399-022-01331-w. Epub 2022 Nov 14.ABSTRACTCardiac involvement occurs in an almost one quarter of all the patients with lung cancer. Lymphatogenous spread is a more common route of tumor dissemination than the hematogenous spread. It was a retrospective case report. We hereby report a case of myocardial involvement by non-small cell lung cancer leading to an uncommon presentation of a malignant stroke and death in a peritoneal dialysis patient.PMID:36404986 | PMC:PMC9662106 | DOI:10.1007/s42399-022-01331-w
Source: Clinical Lung Cancer - November 21, 2022 Category: Cancer & Oncology Authors: Sahil Bagai Vipra Malik Pallavi Prasad Priyanka Singh Amit Sahu Dinesh Khullar Source Type: research
Bioinformatic analysis and clinical diagnostic value of hsa_circ_0004099 in acute ischemic stroke
This study investigates the expression and effect of hsa_circ_0004099 in acute ischemic stroke (AIS). We conducted a case-controlled study that included 40 patients with AIS within 24 hours and 40 healthy subjects during the same period as a control group. Differentially expressed circular RNAs (circRNAs) were obtained using GEO2R, and the expression of hsa_circ_0004099 was verified using RT-PCR. Correlation analysis of the National Institutes of Health Stroke Scale (NIHSS) disease severity score and ischemic time with hsa_circ_0004099 expression levels was also performed. The receiver operating characteristic (ROC) curve ...
Source: Cancer Control - November 18, 2022 Category: Cancer & Oncology Authors: Jiqing Zheng Shuiming Luo Yaobin Long Source Type: research
Assessment of National Program for Prevention and Control of Cancer, Diabetes, CVD and Stroke (NPCDCS): An observational study in rural Jaipur, Rajasthan
CONCLUSION: The study concludes that the implementation of NPCDCS program activities is not in synch with the health staff awareness level. IEC activities were deficient and no work was done for adoption of behavioural change and healthy lifestyle. Actual cases of hypertension were more while cases of diabetes were less than the reported cases found on cross-check survey.PMID:36387714 | PMC:PMC9648218 | DOI:10.4103/jfmpc.jfmpc_2281_21
Source: Cancer Control - November 17, 2022 Category: Cancer & Oncology Authors: Sadhana Meena Monika Rathore Ajay Gupta Pragya Kumawat Arpit Singh Source Type: research
Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
Front Nutr. 2022 Nov 1;9:1007816. doi: 10.3389/fnut.2022.1007816. eCollection 2022.ABSTRACTMany local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation. The GSH tripeptide (γ- L-glutamyl-L-cysteinyl-glycine), the most abundant w...
Source: Cancer Control - November 17, 2022 Category: Cancer & Oncology Authors: Carlos A Labarrere Ghassan S Kassab Source Type: research
The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease
Sickle cell disease (SCD) is complicated by neurologic complications including vasculopathy, hemorrhagic or ischemic overt stroke, silent cerebral infarcts and cognitive dysfunction. Patients with SCD, even in the absence of vasculopathy or stroke, have experience cognitive dysfunction that progresses with age. Transcranial Doppler ultrasound and structural brain MRI are currently used for primary and secondary stroke prevention, but laboratory or imaging biomarkers do not currently exist that are specific to the risk of cognitive dysfunction in patients with SCD. Recent investigations have used advanced MR sequences asses...
Source: Hematology/Oncology Clinics of North America - November 16, 2022 Category: Cancer & Oncology Authors: Kristie Ramos, Kristin P. Guilliams, Melanie E. Fields Source Type: research
Study Protocol and Baseline Characteristics of Randomized Trial for Evaluating Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, The Combination of a Randomized Control Trial and an Observational Biomarker Study
CONCLUSIONS: After this study is completed, we will have further evidence on whether a highly purified EPA is effective in reducing cardiovascular events for secondary prevention or not, as well as whether if EPA/AA ratio is a predictor for future cardiovascular events.PMID:36372250 | DOI:10.1016/j.ahj.2022.11.008
Source: Cancer Control - November 13, 2022 Category: Cancer & Oncology Authors: Yuji Nishizaki Katsumi Miyauchi Hiroshi Iwata Teruo Inoue Atsushi Hirayama Kazuo Kimura Yukio Ozaki Toyoaki Murohara Kenji Ueshima Yoshihiro Kuwabara Sachiko Tanaka-Mizuno Naotake Yanagisawa Tosiya Sato Hiroyuki Daida Source Type: research
Resiliency intervention for patient-caregiver dyads in the Neuro-ICU: Study protocol for a single-blind randomized clinical trial
DISCUSSION: If successful, we plan to test RT in a large-scale, multisite hybrid effectiveness-implementation study in Neuro-ICUs across the country. Enhancing psychosocial supports for patients and families could improve health outcomes, healthcare efficiency, and the culture of these units.PMID:36368480 | DOI:10.1016/j.cct.2022.106998
Source: Cancer Control - November 11, 2022 Category: Cancer & Oncology Authors: Ana-Maria Vranceanu Emily C Woodworth Millan R Kanaya Sarah Bannon Ryan A Mace Heena Manglani Brooke A Duarte Christina L Rush Nathaniel R Choukas Ellie A Briskin Joshua Cohen Robert Parker Eric Macklin Ethan Lester Lara Traeger Jonathan Rosand Karon M Ko Source Type: research
Association Between Aromatase Inhibitors and Myocardial Infarction Morbidity in Women With Breast Cancer: A Meta-Analysis of Observational Studies
CONCLUSION: Based on real-world data, AIs may be a safe treatment route for patients with estrogen receptor-positive breast cancer and those with a history of CVD. AIs caused a major decrease in MI in patients without CVD history. However, more in-depth investigations are needed to explore the association between AI use and the incidence of MI in the treatment of estrogen receptor-positive breast cancer.PMID:36346929 | DOI:10.1177/10732748221132512
Source: Cancer Control - November 8, 2022 Category: Cancer & Oncology Authors: Jing-Chao Sun Ze-Fan Sun Chao-Jie He Chang-Lin Zhai Gang Qian Source Type: research
The effect of voice training interventions on patients with oropharyngeal dysphagia: a systematic review
CONCLUSIONS: In general, statistically significant positive therapy effects were found. Voice training improves the oral and pharyngeal stages of swallowing in patients with neurological causes of dysphagia, such as stroke, and in patients with non-neurological causes of dysphagia, such as head and neck cancer. However, the current literature is limited and further primary research is required to provide more evidence to support voice training intervention in dysphagia. Future studies could further refine the content of voice training interventions, increase the number of patients enrolled, assess the long-term effects of ...
Source: Cancer Control - November 7, 2022 Category: Cancer & Oncology Authors: Chunyan Niu Wenyan Zhou Haifang Wang Yingying Zhang Jianzheng Cai Nini Lu Yalan Wang Source Type: research
Admission Rates, Time Trends, Risk Factors, and Outcomes of Ischemic and Hemorrhagic Stroke From German Nationwide Data
DISCUSSION: Despite recent advances in acute stroke care over the last decade, the percentage of stroke hospitalizations resulting in death remained unchanged. Further research is needed to determine how best to optimize stroke care pathways for multimorbid patients.PMID:36332988 | DOI:10.1212/WNL.0000000000201259
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Dearbhla M Kelly Jannik Feld Peter M Rothwell Holger Reinecke Jeanette Koeppe Source Type: research
Trimethylamine N-Oxide as a potential risk factor for non-communicable diseases: A systematic review
CONCLUSION: There is a dose-response relationship between TMAO levels and NCDs progression. Therefore, it can be studied as a therapeutic target or prognostic biomarker for dealing with NCDs.PMID:36330632 | DOI:10.2174/1871530323666221103120410
Source: Cancer Control - November 4, 2022 Category: Cancer & Oncology Authors: Zahra Hoseini Tavassol Hanieh-Sadat Ejtahed Bagher Larijani Shirin Hasani-Ranjbar Source Type: research
