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Zero-contrast imaging for the assessment of transcatheter aortic valve implantation in candidates with renal dysfunction
CONCLUSION: The proposed contrast-free imaging protocol appears to be a promising clinical tool for pre-TAVI evaluation in patients with severe renal dysfunction.PMID:37350345 | DOI:10.1080/0886022X.2023.2224888
Source: Renal Failure - June 23, 2023 Category: Urology & Nephrology Authors: Guy F A Prado Stefano Garzon Jose Mariani Adriano Caixeta Breno O Almeida Felipe O Ramalho Marcelo L C Vieira Claudio H Fischer Gilberto Szarf Walther Ishikawa Pedro A Lemos Source Type: research

Catastrophic kidney infarction
A 62-year-old man with a history of stroke, ischemic cardiomyopathy, and paroxysmal atrial fibrillation not on anticoagulation presented with left lower extremity weakness and numbness and was found to have left lower extremity ischemia on examination. There was also evidence of acute kidney injury with a serum creatinine level of 2.1 mg/dl from 0.8 mg/dl at baseline. A computed tomography angiogram of the abdomen and pelvis with distal runoff revealed the occlusion of the left common femoral artery and right saphenofemoral artery.
Source: Kidney International - January 1, 2022 Category: Urology & Nephrology Authors: Nattawat Klomjit, Ladan Zand Tags: Nephrology Image Source Type: research

Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD.
CONCLUSIONS: Higher serum uromodulin is independently associated with lower risk for mortality, cardiovascular events, and kidney failure in white patients with CKD. CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: Deutsches Register für Klinische Studien (DRKS; German national database of clinical studies), DRKS00003971. PMID: 32291270 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - April 13, 2020 Category: Urology & Nephrology Authors: Steubl D, Schneider MP, Meiselbach H, Nadal J, Schmid MC, Saritas T, Krane V, Sommerer C, Baid-Agrawal S, Voelkl J, Kotsis F, Köttgen A, Eckardt KU, Scherberich JE, GCKD Study Investigators Tags: Clin J Am Soc Nephrol Source Type: research

Patients with Atrial Fibrillation and Chronic Kidney Disease More Often Undergo Angioplasty of Left Main Coronary Artery – a 867 Patient Study
Conclusion: Patients with CKD had more often permanent type of AF. Percutaneous interventions of the left main coronary artery, the only elective procedures influencing patients ’ prognosis, were done more frequently in CKD patients with AF. In-hospital mortality was significantly higher in patients with severe renal impairment. Despite the higher risk of ischaemic stroke in CKD group the use of oral anticoagulation therapy was significantly less frequent and the patients were deprived of the confirmed benefits of such treatment.Kidney Blood Press Res 2018;43:1796 –1805
Source: Kidney and Blood Pressure Research - November 30, 2018 Category: Urology & Nephrology Source Type: research

Preoperative Cardiac Evaluation in Kidney Transplant Patients: Is Coronary Angiography Superior? A Focused Review.
Authors: Katta N, Balla S, Velagapudi P, Mittal M, Agrawal H, Kumar A, Aggarwal K Abstract Cardiovascular disease is the major cause of morbidity and mortality in chronic kidney disease patients. Because of a higher occurrence of asymptomatic coronary artery disease and increased perioperative cardiovascular mortality in kidney transplant patients, screening for coronary artery disease before transplant surgery is essential. Various studies have shown that cardiac stress testing is an unreliable screening method in these patients because of significant variability in sensitivity and negative predictive value. We su...
Source: Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis - October 13, 2017 Category: Urology & Nephrology Tags: Adv Perit Dial Source Type: research

Associations among serum trimethylamine-N-oxide (TMAO) levels, kidney function and infarcted coronary artery number in patients undergoing cardiovascular surgery: a cross-sectional study
Conclusions Higher serum TMAO levels may be associated with advanced CKD stages and with an increased number of infarcted coronary arteries in patients who undergo cardiovascular surgery.
Source: Clinical and Experimental Nephrology - December 16, 2015 Category: Urology & Nephrology Source Type: research

Circulating tumour necrosis factor receptors 1 and 2 predict contrast‐induced nephropathy and progressive renal dysfunction: A prospective cohort study
ConclusionMarkedly elevated concentrations of circulating TNFRs were correlated with the occurrence of CIN and significantly associated with prolonged renal dysfunction regardless of the development of CIN.
Source: Nephrology - July 21, 2015 Category: Urology & Nephrology Authors: Jung Nam An, Kyung Don Yoo, Jin Ho Hwang, Hack‐Lyoung Kim, Sang‐Hyun Kim, Seung Hee Yang, Jin Hyuk Kim, Dong Ki Kim, Yun Kyu Oh, Yon Su Kim, Chun Soo Lim, Jung Pyo Lee Tags: Original Article Source Type: research

Circulating tumor necrosis factor receptors 1 and 2 predict contrast‐induced nephropathy and progressive renal dysfunction: a prospective cohort study
ConclusionMarkedly elevated concentrations of circulating TNFRs were correlated with the occurrence of CIN and significantly associated with prolonged renal dysfunction regardless of the development of CIN.
Source: Nephrology - March 1, 2015 Category: Urology & Nephrology Authors: Jung Nam An, Kyung Don Yoo, Jin Ho Hwang, Hack‐Lyoung Kim, Sang‐Hyun Kim, Seung Hee Yang, Jin Hyuk Kim, Dong Ki Kim, Yun Kyu Oh, Yon Su Kim, Chun Soo Lim, Jung Pyo Lee Tags: Original Article Source Type: research

Impact of impaired glomerular filtration rate and revascularization strategy on one-year cardiovascular events in acute coronary syndrome: data from Taiwan acute coronary syndrome full spectrum registry
Background: The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. Methods: In a Taiwan national-wide registry, 3093 ACS patients were enrolled. The invasive strategy was defined as patients with ST-elevation ACS (STE-ACS) undergoing primary angioplasty or fibrinolysis or coronary angiography with intent to revascularization performed within 72 hours of symptom onset in non-ST-elevation ACS (NSTE-A...
Source: BMC Nephrology - April 23, 2014 Category: Urology & Nephrology Authors: Tsung-Hsien LinHo-Tsung HsinChun-Li WangWen-Ter LaiAi-Hsien LiChi-Tai KuoJuey-Jen HwangFu-Tien ChiangShu-Chen ChangChee Chang Source Type: research

Renovascular hypertension: A report of 21 cases.
Abstract Renovascular hypertension (RVH) is among the most common forms of secondary hypertension. We studied 21 patients (eight male and 13 female) with RVH who were encountered during a period of 16 years. The average age of the patients was 34.75 years. Trans-renal Doppler ultrasound confirmed the diagnosis of renovascular stenosis (RAS) as the cause of RVH in 95% of the patients. Computed tomography angiography was performed in ten cases, which confirmed the diagnosis in all these cases. Magnetic resonance angiography was performed in only three patients. Renal scintigraphy was performed in 11 patients, with D...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2014 Category: Urology & Nephrology Authors: Labidi J, Touat D, Abdelghanim K, Ajili F, Ariba YB, Abdelhafidh NB, Louzir B, Othmani S Tags: Saudi J Kidney Dis Transpl Source Type: research

Plasma Ceruloplasmin, a Regulator of Nitric Oxide Activity, and Incident Cardiovascular Risk in Patients with CKD.
CONCLUSION: In CKD patients, increased serum ceruloplasmin, a regulator of nitric oxide activity, is associated with increased risk of long-term adverse cardiovascular events, even after multivariable model adjustment for traditional clinical and biologic risk factors. PMID: 24311705 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - December 5, 2013 Category: Urology & Nephrology Authors: Kennedy DJ, Fan Y, Wu Y, Pepoy M, Hazen SL, Tang WH Tags: Clin J Am Soc Nephrol Source Type: research

What lies beneath: Fabry nephropathy in a female patient with severe cerebrovascular disease.
We report a novel presentation of Fabry disease in a female patient with medical history of relapsing strokes and brain magnetic resonance angiography showing signs of microangiopathy and multiple lacunar strokes that were first diagnosed as Moyamoya disease (a chronic progressive cerebrovascular disease). The patient subsequently displayed increased levels of serum creatinine and proteinuria. Diagnosis of Fabry disease was made by a renal biopsy and was confirmed by molecular studies showing a missense mutation: c1066C > T (het) [R356W]. The diagnosis was delayed by 21 years with respect to her first symptom (stroke), ...
Source: Clinical Nephrology - April 1, 2013 Category: Urology & Nephrology Authors: Romão EA, Lourenço CM, Júnior WM, Rolfs A, Muñoz V, Vieira Neto OM, Dantas M, Silva GE, Costa RS Tags: Clin Nephrol Source Type: research