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Total 22 results found since Jan 2013.

Moyamoya and childhood stroke: Catching up with Tyler and Ryan
Ryan (above left) and Tyler Earle of Winnipeg, Canada had a ticking time bomb inside their heads. Both boys have a rare brain disorder called moyamoya that had caused the arteries feeding their brains to become dangerously narrowed. At first, they experienced only headaches. But then Ryan suddenly lost his ability to write, began having trouble with word-finding and became weak on one side of his body — signs he had suffered a stroke. He was diagnosed with moyamoya and had partial surgery, but a second stroke took away part of his vision and partially paralyzed him. Ryan needed a second operation as soon as possible. By ...
Source: Thrive, Children's Hospital Boston - May 12, 2016 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Cerebrovascular Disorders and Stroke Program Dr. Edward Smith moyamoya Source Type: news

Twin surgeries bring this family a stroke of luck
Ryan Earle is outgoing and upbeat, goofing around in his neurosurgeon’s office. He’s had two strokes, but he’s recovering steadily, a testament to the resilience of children’s brains. His twin brother Tyler, with him at the visit, has avoided a likely stroke altogether. Both Ryan and Tyler, 8, have a rare brain disorder called moyamoya disease, in which the internal carotid arteries become narrowed, slowing the flow of blood to their brains. Without surgery, moyamoya poses a five-year stroke risk of 60 to 90 percent. The boys’ moyamoya symptoms were subtle: “They would have a mild headache, then they’d throw ...
Source: Thrive, Children's Hospital Boston - December 29, 2014 Category: Pediatrics Authors: Lisa Fratt Source Type: news

Superhero Joey: Five-year-old fights moyamoya disease
It’s been said that not all heroes wear capes — but Joey Gallagher owns several. The five-year-old has already amassed a collection of superhero gear, from a Superman Halloween costume to a t-shirt emblazoned with the Batman logo. Yet even the most diehard comic book fan would likely admit that feats like flying, leaping tall buildings and fighting bad guys don’t hold a candle to the challenges this little boy has already surmounted. Just last June, Joey was out of town with his family when he had what his parents, Leila and Scott, feared was a seizure. Clinicians in the emergency department dismissed the event as he...
Source: Thrive, Children's Hospital Boston - April 4, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories childhood stroke Dr. Edward Smith Dr. Michael Scott moyamoya Moyamoya Disease Program Source Type: news

Precise neonatal arterial ischemic stroke classification with a three-dimensional map of the arterial territories of the neonatal brain.
CONCLUSION: The ATNB map has been proven useful to precisely identify the arterial territories affected by an NAIS, as well as to increase the accuracy of clinical diagnoses. PMID: 31835270 [PubMed - as supplied by publisher]
Source: Pediatric Research - December 12, 2019 Category: Pediatrics Authors: Núñez C, Arca G, Agut T, Stephan-Otto C, García-Alix A Tags: Pediatr Res Source Type: research

Question 2: Neurological complications of diagnostic cerebral catheter angiography in children
Scenario An 8-year-old boy is currently an inpatient in your paediatric unit having had a sudden onset of left sided weakness after a roller-coaster ride. Brain MRI has shown this to be due to a right-sided pontine infarct; brain and neck magnetic resonance angiography (MRA) were normal. Assessment has not identified any risk factors for arterial ischaemic stroke (AIS). Transfer has been arranged to the tertiary centre, where the paediatric neurologists are planning to request diagnostic catheter cerebral angiography (CA) to exclude vertebral artery dissection. The child's parents are apprehensive about this and would like...
Source: Archives of Disease in Childhood - April 9, 2014 Category: Pediatrics Authors: McCrea, N., Robertson, F., Ganesan, V. Tags: ADC Archimedes, Neuroimaging, Neurological injury, Stroke, Child and adolescent psychiatry (paedatrics), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Trauma, Injury Source Type: research

Utility of Neurovascular Imaging in Acute Neonatal Arterial Ischemic Stroke
To evaluate the prevalence of magnetic resonance angiography (MRA) findings and clinically characterize neonates with arterial ischemic stroke (AIS) who have abnormal or variable vasculature.
Source: The Journal of Pediatrics - June 14, 2017 Category: Pediatrics Authors: Ishita Siddiq, Derek Armstrong, Ann-Marie Surmava, Nomazulu Dlamini, Daune MacGregor, Mahendranath Moharir, Rand Askalan Tags: Original Articles Source Type: research

Varicella-Associated Stroke
A previously healthy, unimmunized 11-month-old boy presented with acute right-sided weakness. On the day of presentation, his mother noted that his right arm and leg seemed to be weak when she woke him from his usual afternoon nap. Evaluation at an urgent care center confirmed right-sided facial weakness, decreased strength and movement of his right upper and lower extremities, and a lack of right-sided support in a sitting position. Computed tomography of the head without contrast was normal. He was transferred to a regional care center where head magnetic resonance imaging and magnetic resonance angiography demonstrated ...
Source: The Journal of Pediatrics - April 19, 2018 Category: Pediatrics Authors: Surabhi B. Vora, Catherine Amlie-Lefond, Francisco A. Perez, Ann J. Melvin Tags: Insights and Images Source Type: research

From Bermuda to Boston for surgery to protect the brain of a boy with sickle cell disease
Calvin Steede, who lives in Bermuda, will never forget the day in 2011 when he saw the movie “Winnie the Pooh” with his mother and sister. The film ended, and suddenly the boy who likes to draw and play soccer couldn’t put on his backpack. His arms had stopped working. He couldn’t stand, and soon he couldn’t talk. Calvin, now 11, had suffered a minor stroke, a complication of sickle cell disease and the first step of a journey that would take him to Dana-Farber/Boston Children’s Cancer and Blood Disorders Center for minimally invasive surgery to protect his brain from future strokes. Sickle cell disease Sickle ...
Source: Thrive, Children's Hospital Boston - June 19, 2015 Category: Pediatrics Authors: Irene Sege Tags: Diseases & conditions Dana-Farber/Boston Children's Cancer and Blood Disorders Center moyamoya sickle cell disease Source Type: news

Fighting for Kennedy: Coping with moyamoya disease
If you happen to be waiting in line at the supermarket with Kennedy Grace Cheshire, you’ll likely leave the store with a whole new group of friends. This outgoing five-year-old can’t resist introducing herself to her fellow shoppers — and then introducing them to each other. “She’s never met a stranger,” says her mother, Amber. Kennedy, who lives in Texas, brought that playful attitude to the East Coast last year when she and her family arrived at Boston Children’s Hospital for evaluation and treatment. At age two, she had been diagnosed with neurofibromatosis 1 (NF1), a genetic condition that causes symptoms...
Source: Thrive, Children's Hospital Boston - March 21, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dr. Edward Smith moyamoya Moyamoya Disease Program Source Type: news

After Moyamoya surgery, a back-to-normal birthday for Carolyn
Before Moyamoya surgery Carolyn Milks turns 8 on August 21. It’s a big celebration. Carolyn and her family aren’t just celebrating her birthday — they’re celebrating Carolyn’s return to normal. For most of the summer, things like swimming, riding her bicycle and horsing around with her sisters and cousins had been out of the question for Carolyn. But on August 11, Dr. Ed Smith, co-director of the Boston Children’s Hospital Cerebrovascular Surgery and Interventions Center, gave Carolyn the green light. She could go back to being a kid. “This is what kids really want. They just want to ...
Source: Thrive, Children's Hospital Boston - August 18, 2016 Category: Pediatrics Authors: Joyce Choi Tags: Our Patients’ Stories Boston Children's at Waltham Cerebrovascular Surgery and Interventions Center Dr. Ed Smith moyamoya Source Type: news

Neonatal cervical artery dissection secondary to birth trauma.
We report a case of a male newborn who was born vaginally after shoulder dystocia. The extraction was difficult, resulting in a fracture of the right humerus. On the second day of life, the child presented generalized clonic convulsions. Computed tomography of the brain showed an ischemic stroke in the territory of the right middle cerebral artery, the territory of the right posterior cerebral artery, and the right lenticulostriate and capsular regions. Doppler ultrasonography and magnetic resonance angiography showed bilateral carotid artery thrombosis and dissection at the left common carotid artery and its two branches ...
Source: Archives de Pediatrie - November 26, 2013 Category: Pediatrics Authors: Hamida N, Hakim A, Fourati H, Ben Thabet A, Walha L, Bouraoui A, Mnif Z, Gargouri A Tags: Arch Pediatr Source Type: research

Childhood cerebral vasculitis.
Abstract Central nervous system vasculitides are defined as the invasion of the vascular wall by blood-borne inflammatory cells. In childhood, they may be classified according to their trigger event (infectious vs. non-infectious), their temporal course (time-limited vs. chronic), and the size of the affected vessel. Diseases apparently confined to the central nervous system are also distinguished from secondary forms, associated with infection or rheumatic or systemic inflammatory disorders. Large-vessel vasculitis, the most frequent form, causes stroke and presents with acute focal deficits. MR, or more seldom c...
Source: Archives de Pediatrie - July 3, 2014 Category: Pediatrics Authors: Chabrier S, Darteyre S, Mazzola L, Stéphan JL Tags: Arch Pediatr Source Type: research

Great Vessels of Children: Takayasu's Arteritis.
Abstract Takayasu's arteritis (TA) is a granulomatous, large vessel vasculitis affecting primarily the aorta and its main branches. It is characterized by inflammation in the blood vessel wall, leading to either luminal occlusion or dilatation with aneurysm formation. The etiology of TA is unknown, but there seems to be a strong role for cell-mediated autoimmunity in the pathogenesis of this disease. TA most commonly presents in young women in their second and third decades of life, but has been reported in children as young as age 2 years. The symptoms can range from vague systemic complaints to catastrophic stro...
Source: Pediatric Annals - June 1, 2015 Category: Pediatrics Authors: de Ranieri D Tags: Pediatr Ann Source Type: research

Severe Cerebral Vasospasm and Childhood Arterial Ischemic Stroke After Intrathecal Cytarabine
We report on 2 patients who developed widespread cerebral vasospasm and arterial ischemic strokes (AIS) after application of intrathecal (IT) cytarabine. In a 3-year-old child with acute lymphoblastic leukemia (ALL), left leg weakness, hyperreflexia, and clonus were noted 4 days after her first dose of IT cytarabine during the induction phase of her chemotherapy. Cerebral MRI revealed multiple acute cerebral ischemic infarcts and widespread cerebral vasospasm. A 5-year-old girl complained of right arm and leg pain and began limping 11 days after IT cytarabine. Symptoms progressed to right dense hemiplegia, left gaze deviat...
Source: PEDIATRICS - February 1, 2016 Category: Pediatrics Authors: Tibussek, D., Natesirinilkul, R., Sun, L. R., Wasserman, B. A., Brandao, L. R., deVeber, G. Tags: Hematology/Oncology, Cancer/Neoplastic, Neurology, Neurologic Disorders Case Report Source Type: research