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The application of pre-hospital first aid mode in patients with acute stroke: meta-analysis
Folia Neuropathol. 2022;60(3):284-291. doi: 10.5114/fn.2022.117614.ABSTRACTTo systematically evaluate the application effect of pre-hospital and in-hospital emergency mode in patients with acute stroke. The study was conducted by systematic search of Chinese (CNKI, Wanfang and VIP) and English (PubMed, EMBASE and Cochrane Library) databases. The case-control studies comparing the role of pre-hospital and in-hospital emergency mode for patients with acute stroke were included in this study. Outcome indicators included the time from admission to thrombolytic therapy (DNT), the time from calling for help to receiving professi...
Source: Folia Neuropathologica - November 16, 2022 Category: Neurology Authors: Xiaoting Zhu Rong Niu Fangfang Bai Zhufeng Zhang Source Type: research

The SON2A2 score: A novel grading scale for predicting hemorrhage and outcomes after thrombolysis
ConclusionThe SON2A2 score is a simple, efficient, quick, and easy-to-perform scale for predicting the risk of sICH and outcome after intravenous r-tPA thrombolysis within 4.5 h in patients with ischemic stroke, and risk assessment using this test has the potential for early and personalized management of this disease in high-risk patients.
Source: Frontiers in Neurology - October 31, 2022 Category: Neurology Source Type: research

The impact of leptomeningeal collaterals in acute ischemic stroke: a systematic review and meta-analysis
ConclusionsThe relative risk of favorable clinical outcome is more in patients with good pretreatment CBF. This could be explained due to better chances of recanalization combined with a lesser risk of intracerebral hemorrhage with good CBF status.
Source: Neurological Sciences - October 4, 2022 Category: Neurology Source Type: research

Successful thrombolytic therapy is associated with increased granulocyte CD15 expression and reduced stroke ‐induced immunosuppression
ConclusionsOur current results indicate that TT may not only acutely reduce the systemic inflammatory response following stroke but may also play a role in reversing SIIS at a later stage following the insult, as reflected by the higher expression of the CD15 marker on granulocytes following successful TT.
Source: Brain and Behavior - September 16, 2022 Category: Neurology Authors: Katalin Anna B éres‐Molnár, Ágnes Czeti, Ferenc Takács, Gábor Barna, Dániel Kis, Gabriella Róka, András Folyovich, Gergely Toldi Tags: ORIGINAL ARTICLE Source Type: research

Moving from traditional to more advanced treatments in stroke care is cost-effective: A case study from Greece
Ischemic stroke (IS) is one of the leading causes of mortality and disability,1, 2 with the economic burden of post-stroke care being substantial.1, 2 After incidence of IS, the following effective treatments have been found to significantly improve survival and quality of life: (a) treatment in specialized centres (Stroke Units; SU), (b) use of intravenous thrombolytic therapy (IVT), (c) use of endovascular thrombectomy (EVT) for patients with large vessel occlusions (LVO) and (d) rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2022 Category: Neurology Authors: Konstantinos Dimitriadis, Ilias Kyriopoulos, Georgios Tsivgoulis, Konstantinos Vemmos, Wolfgang G. Kunz, Elias Mossialos Source Type: research

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