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Specialty: Neurology
Procedure: Angiography

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Total 2194 results found since Jan 2013.

Comprehensive Profiling of Secreted Factors in the Cerebrospinal Fluid of Moyamoya Disease Patients
AbstractMoyamoya disease (MMD) is characterized by progressive occlusion of the intracranial internal carotid arteries, leading to ischemic and hemorrhagic events. Significant clinical differences exist between ischemic and hemorrhagic MMD. To understand the molecular profiles in the cerebrospinal fluid (CSF) of MMD patients, we investigated 62 secreted factors in both MMD subtypes (ischemic and hemorrhagic) and examined their relationship with preoperative perfusion status, the extent of postoperative angiographic revascularization, and functional outcomes. Intraoperative CSF was collected from 32 control and 71 MMD patie...
Source: Translational Stroke Research - February 6, 2023 Category: Neurology Source Type: research

Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). Haptoglobin scavenging of CSF-Hb has been shown to mitigate cerebrovascular disruption. Using digital subtraction angiography (DSA) and blood oxygenation-level dependent cerebrovascular reactivity imaging (BOLD-CVR) the aim was to assess the acute toxic effect of CSF-Hb on cerebral blood flow and autoregulation, as well as to test the protective effects of haptoglobin.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2023 Category: Neurology Authors: Bart R. Thomson, Henning Richter, Kevin Akeret, Raphael M. Buzzi, Vania Anagnostakou, Christiaan H.B. van Niftrik, Nina Schwendinger, Zsolt Kulcsar, Peter W. Kronen, Luca Regli, Jorn Fierstra, Dominik J. Schaer, Michael Hugelshofer Source Type: research

Clinical Burden of Angiographic Vasospasm and Its Complications After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review
ConclusionPatients with angiographic VSP and its related complications often had poor functional, neurological, and cognitive outcomes and reduced odds of survival both in hospital and at follow-up. We estimate that angiographic VSP and its related complications, DCI and cerebral infarction, lead to an approximately threefold higher odds of poor functional and cognitive outcomes, and about a twofold increase in the odds of death.
Source: Neurology and Therapy - January 7, 2023 Category: Neurology Source Type: research

Effect of intra-arterial nimodipine on iatrogenic vasospasms during endovascular stroke treatment – angiographic resolution and infarct growth in follow-up imaging
The treatment of vasospasms during endovascular stroke treatment (EST) with intra-arterial nimodipine (NM) is routinely performed. However, the efficacy of resolving iatrogenic vasospasms during the angiograph...
Source: BMC Neurology - January 5, 2023 Category: Neurology Authors: Jessica Jesser, Arne Potreck, Dominik Vollherbst, Fatih Seker, Min Chen, Silvia Sch önenberger, Thuy D. Do, Martin Bendszus, Markus A. Möhlenbruch and Charlotte S. Weyland Tags: Research Source Type: research

Indirect revascularization vs. non-surgical treatment for Moyamoya disease and Moyamoya syndrome: A comparative effectiveness study
ConclusionIndirect revascularization surgery can significantly reduce the recurrent stroke incidence of MMD and MMS patients.
Source: Frontiers in Neurology - December 19, 2022 Category: Neurology Source Type: research

Low NIHSS score large vessel occlusion caused by infective endocarditis treated with thrombectomy
A 24-year-old woman had undergone dental treatment 3 weeks before and had a mild fever for a week. She presented to the emergency department with the chief complaint of weakness in the right upper limb after waking up. She had mild paralysis of the right upper limb (National Institutes of Health Stroke Scale [NIHSS] score 1). Head magnetic resonance imaging (MRI) showed scattered infarcts in the left frontal and parietal lobes and left internal cerebral artery (ICA) occlusion (Fig. 1A, B). Cerebral angiography showed that the left ICA was occluded immediately after its origin (Fig.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2022 Category: Neurology Authors: So Matsukawa, Kohichi Go, Tao Yang, Takahisa Katsuki, Yohei Takenobu, Kenji Hashimoto Tags: Case Report Source Type: research

Endovascular treatment of acute ischemic stroke with a fully radiopaque retriever: A randomized controlled trial
ConclusionThe Neurohawk retriever is non-inferior to the Solitaire FR in the mechanical thrombectomy of large vessel occlusion-acute ischemic stroke (LVO-AIS). The sub-analysis suggested that endovascular treatment including thrombectomy with the retriever and essential rescue angioplasty is effective and safe in AIS patients with intracranial atherosclerotic disease-larger vessel occlusion (ICAD-LVO).Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/NCT04995757, number: NCT04995757.
Source: Frontiers in Neurology - December 15, 2022 Category: Neurology Source Type: research

How to Avoid Misdiagnosing Spontaneous Cervical Spinal Epidural Hematoma as Ischemic Stroke: 3 Case Reports and Literature Review
We reported 3 SCEH patients who were initially suspected as IS in our center between Jun 2020 and April 2022 and analyzed their clinical characteristics together with 48 patients reported in the literature from Jan 1995 to April 2022. Two of the 3 SCEH patients had neck symptoms, while none of them presented cranial nerve symptoms. Cranial computed tomography (CT) scans were negative; however, abnormal signals in the cervical spinal canal were observed during cranial computed tomography angiography (CTA) and subsequent cervical CT confirmed the diagnosis of SCEH. All of them avoid mistreatment with recombinant tissue plasm...
Source: Cerebrovascular Diseases - December 14, 2022 Category: Neurology Source Type: research

HIV-associated multiple intracranial aneurysms and stroke in an adult patient: successful treatment with a combination of glucocorticoid and antiviral agents
AbstractA 35-year-old Iranian man with an 18-year history of human immunodeficiency virus (HIV) infection developed sudden left-sided hemiparesis and mild dysarthria. Based on laboratory results, brain and neck computerized tomography angiography (CTA), echocardiography, hypercoagulability tests, and vasculitis tests, the patient was diagnosed with a stroke with multiple intracranial aneurysms secondary to HIV. Cerebral aneurysms and stroke are uncommon in HIV-infected patients, and the aneurysms ’ exact cause and risk factors are unknown. There is currently no effective regimen or definitive treatment for HIV-associated...
Source: Journal of NeuroVirology - December 13, 2022 Category: Neurology Source Type: research

Left atrial appendage thrombus in acute stroke: diagnostic accuracy of CT angiography compared to transesophageal echocardiography
To evaluate the value of an extended emergency computed tomography angiography (CTA) including cardiac imaging in patients with acute ischemic stroke for the detection of left atrial appendage (LAA) thrombus compared to transesophageal echocardiography (TEE) as a reference standard.
Source: Journal of Stroke and Cerebrovascular Diseases - December 13, 2022 Category: Neurology Authors: Jo ão Pinho, Laurien Dhaenens, Jan Heckelmann, Manuel Dafotakis, Rebecca May, Martin Wiesmann, Jörg Bernhard Schulz, Oliver Matz Source Type: research

Visualization of both proximal M2-MCA segments in patients (the Tilted-V Sign) with acute M1-MCA occlusion stroke is associated with better procedural and prognostic outcomes
ConclusionTilted-V Sign, an easily identifiable radiological marker, is associated with fewer recanalization attempts, better functional outcomes, and reduced mortality.
Source: Frontiers in Neurology - December 13, 2022 Category: Neurology Source Type: research

Automated detection of intracranial large vessel occlusions using Viz.ai software: Experience in a large, integrated stroke network
ConclusionsViz.ai-LVO has high specificity and moderately high sensitivity to detect an ICA or proximal MCA occlusion. The software has the potential to streamline code stroke workflows and may be particularly impactful when emergency access to NRs or vascular neurologists is limited.
Source: Brain and Behavior - December 2, 2022 Category: Neurology Authors: Rahul R. Karamchandani, Anna Maria Helms, Sagar Satyanarayana, Hongmei Yang, Jonathan D. Clemente, Gary Defilipp, Dale Strong, Jeremy B. Rhoten, Andrew W. Asimos Tags: ORIGINAL ARTICLE Source Type: research

Elderly onset of MELAS in a male: A case report
ConclusionElderly onset of MELAS is rare and easily misdiagnosed as an ischemic stroke. MELAS with the onset of stroke-like episodes should be considered in adult or elderly patients with imaging findings that are atypical for cerebral infarction. The use of multimodal MRI in the clinical diagnosis of MELAS could be extremely beneficial.
Source: Frontiers in Neurology - December 1, 2022 Category: Neurology Source Type: research

Relevance of admission hyperglycaemia and diabetes mellitus to efficacy and safety of mechanical thrombectomy in stroke patients
CONCLUSIONS: Diabetes mellitus has a neutral effect on the angiographic and clinical outcomes of mechanical thrombectomy in stroke patients. It does not increase the risk of intracranial haemorrhage after instrumental therapy. It is admission hyperglycaemia, rather than diabetes mellitus, that is a predictor of poor functional status in patients treated with thrombectomy. According to our results, the patient's neurological status, age, and the outcome of thrombectomy are relevant to the functional status in the acute ischaemic stroke period.PMID:36394219 | DOI:10.5603/PJNNS.a2022.0063
Source: Neurologia i Neurochirurgia Polska - November 17, 2022 Category: Neurology Authors: Anetta Lasek-Bal Amadeusz Żak Łukasz Binek Sebastian Student Aleksandra Cie ślik Wies ław Bal Wiktor Rybicki Jolanta Kulawik-Szwajca Source Type: research