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Total 386 results found since Jan 2013.

Acute ischemic stroke and abnormal blood hemoglobin concentration
ConclusionsOur results suggest that an elevated HGB on the initial admission is associated with more severe strokes, greater disability at discharge, and higher 30‐day mortality after AIS. A low HGB on admission is associated with longer stay in the acute care hospital.
Source: Acta Neurologica Scandinavica - October 21, 2015 Category: Neurology Authors: J. C. Furlan, J. Fang, F. L. Silver Tags: Original Article Source Type: research

Cancer-Associated Stroke: The Bergen NORSTROKE Study
Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of necrotizing factor and interleukins may cause inflammation of the endothelial lining, creating a prothrombotic surface that triggers thromboembolic events, including stroke. The aims of this study were to assess the occurrence of cancer in patients who had recently suffered an ischemic stroke and to detect possible associations between stroke and cancer subtypes. Methods: All ischemic stroke patients registe...
Source: Cerebrovascular Diseases Extra - October 13, 2015 Category: Neurology Source Type: research

Clinical Reasoning: A 68-year-old man with a history of lung cancer presenting with right-sided weakness and aphasia
A 68-year-old man with paroxysmal atrial fibrillation on warfarin, left subclavian thrombosis treated with carotid-subclavian bypass, and lung adenocarcinoma treated with pneumonectomy, chemotherapy, and prophylactic cranial irradiation and in remission since 1987 was admitted to our neurocritical care unit with acute onset of right-sided weakness, expressive aphasia, and lethargy. On admission his temperature was 101.7°F, and initial blood pressure was 140/60 mm Hg. There was no nuchal rigidity. He was alert and mute with impaired comprehension. He had left gaze preference. Vision was impaired in the right field. Ther...
Source: Neurology - October 5, 2015 Category: Neurology Authors: Gupta, A., Etherton, M. R., McKee, K., Baker, J. M., Izzy, S., Feske, S. K. Tags: All Cerebrovascular disease/Stroke, Radiation therapy-tumor, All Epilepsy/Seizures RESIDENT AND FELLOW SECTION Source Type: research

Chronic disease and lifestyle factors associated with change in sleep duration among older adults in the Singapore Chinese Health Study
This study aimed to identify factors associated with change in sleep duration in a large sample of older adults (≥ 60 years) residing in Singapore (n = 10 335). These adults were monitored as part of the Singapore Chinese Health Study, which collected information regarding daily sleep duration at baseline (assessed in 1993–1998) and at a follow‐up wave conducted over a mean of 12.7 years later (assessed in 2006–2010). Among adults sleeping 6–8 h at baseline (n = 8265), most participants (55.6%) remained 6–8 h sleepers at follow‐up, while 8.4% became short (< 6 h) and 36.0% became long (> 8...
Source: Journal of Sleep Research - September 28, 2015 Category: Neurology Authors: Stephen F. Smagula, Woon‐Puay Koh, Renwei Wang, Jian‐Min Yuan Tags: Regular Research Paper Source Type: research

Recurrent stroke in childhood cancer survivors
Conclusion: Survivors of childhood cancer, particularly those previously treated with high-dose cranial radiation, have a high risk of recurrent stroke for decades after a first stroke. Although these strokes are mostly occurring in young adulthood, hypertension, an established atherosclerotic risk factor, independently predicts recurrent stroke in this population.
Source: Neurology - September 21, 2015 Category: Neurology Authors: Fullerton, H. J., Stratton, K., Mueller, S., Leisenring, W. W., Armstrong, G. T., Weathers, R. E., Stovall, M., Sklar, C. A., Goldsby, R. E., Robison, L. L., Krull, K. R. Tags: Childhood stroke, Stroke in young adults, All Cerebrovascular disease/Stroke, Primary brain tumor ARTICLE Source Type: research

Mortality and comorbidities in patients with multiple sclerosis compared with a population without multiple sclerosis: An observational study using the US department of defense administrative claims database
Conclusions Rates of mortality and several comorbidities are higher in the MS versus non-MS cohort. Early recognition and management of comorbidities may reduce premature mortality and improve quality of life in patients with MS.
Source: Multiple Sclerosis and Related Disorders - August 19, 2015 Category: Neurology Source Type: research

A cross-sectional evaluation of home health service in patients with chronic neurologic diseases in a province of Turkey
In this study, we aimed to compare patients’ characteristics, comorbid risk factors, medical supplies, and caregivers’ demographics between stroke patients and patients with other chronic neurological diseases receiving home health services. In our study, between November 2013 and March 2014, chronic neurological disease (CND) patients having home health services were enrolled in the study. During patient visits, patients were assessed by the questionnaire comprising the modified Rankin scale (mRS), Barthel index, Zarit caregiver burden scale, and mini nutritional assessment (MNA). Stroke patients were classified as Gr...
Source: Acta Neurologica Belgica - July 19, 2015 Category: Neurology Source Type: research

Association between incident cancer and subsequent stroke
Source: Annals of Neurology - July 14, 2015 Category: Neurology Authors: Jesús González de la Aleja, Antonio Martínez‐Salio, Julián Benito‐León Tags: Letter to the Editor Source Type: research

Normal neuronal firing may spark brain tumor growth
Using human brain tumor samples, scientists have discovered that normal patterns of nerve cell firing may enhance the growth of cancer cells. They also found that, neuroligin-3 (NLGN3), a gene known to be important for brain cell communication, may influence tumor growth and patient survival, making it a potential new target for therapy. The study, published in Cell, was partially funded by the National Institutes of Health (NIH).
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - June 16, 2015 Category: Neurology Source Type: news

Intakes of magnesium, potassium, and calcium and the risk of stroke among men
ConclusionsA diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Because of significant collinearity, the independent contribution of each cation is difficult to define.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Sally N. Adebamowo, Donna Spiegelman, Alan J. Flint, Walter C. Willett, Kathryn M. Rexrode Tags: Research Source Type: research

Circulating Tissue Factor Levels and Risk of Stroke: Findings From the EPICOR Study Clinical Sciences
Conclusions— Our data provide evidence that elevated levels of circulating TF are potential risk factors for ischemic strokes.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Iacoviello, L., Di Castelnuovo, A., de Curtis, A., Agnoli, C., Frasca, G., Mattiello, A., Matullo, G., Ricceri, F., Sacerdote, C., Grioni, S., Tumino, R., Napoleone, E., Lorenzet, R., de Gaetano, G., Panico, S., Donati, M. B. Tags: Risk Factors, Coagulation, Acute Cerebral Hemorrhage Clinical Sciences Source Type: research

Cancer in Young Adults With Ischemic Stroke Clinical Sciences
Conclusions— Cancer, and especially active cancer and no other apparent cause for stroke, is associated with unfavorable survival among young stroke patients.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Aarnio, K., Joensuu, H., Haapaniemi, E., Melkas, S., Kaste, M., Tatlisumak, T., Putaala, J. Tags: Acute Cerebral Infarction, Risk Factors for Stroke, Stroke in Children and the Young Clinical Sciences Source Type: research

Study points to possible treatment for lethal pediatric brain cancer
Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), an aggressive and lethal form of pediatric cancer.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - May 4, 2015 Category: Neurology Source Type: news

Multivitamin Use and Risk of Stroke Mortality: The Japan Collaborative Cohort Study Clinical Sciences
Conclusions— Multivitamin use, particularly frequent use, was associated with reduced risk of total and ischemic stroke mortality among Japanese people with lower intake of fruits and vegetables.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Dong, J.-Y., Iso, H., Kitamura, A., Tamakoshi, A., Japan Collaborative Cohort Study Group Tags: Primary prevention, Epidemiology Clinical Sciences Source Type: research

Predictors of Occult Cancer in Acute Ischemic Stroke Patients
We investigated the prevalence of occult malignancy (OM) in acute ischemic stroke patients to evaluate if any biological marker could help to detect the presence of OM.
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2015 Category: Neurology Authors: Dolores Cocho, Jordi Gendre, Anuncia Boltes, Jordi Espinosa, Ana C. Ricciardi, Jordi Pons, Marta Jimenez, Pilar Otermin Source Type: research