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Total 345 results found since Jan 2013.
Obstructive sleep apnea is independently associated with subclinical coronary atherosclerosis among middle-aged women.
CONCLUSION: Moderate to severe OSA is independently associated with the presence of CAC in middle-aged women. These results reinforce the concept that women are also susceptible to the cardiovascular consequences of OSA.
PMID: 27384043 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - July 5, 2016 Category: Sleep Medicine Authors: Medeiros AK, Coutinho RQ, Barros IM, Costa LO, Leite AP, Bittencourt MS, Lustosa TC, Carvalho MM, Lira MP, Ferreira MN, Lorenzi-Filho G, Drager LF, Pedrosa RP Tags: Sleep Breath Source Type: research
Comparison of in-laboratory and home diagnosis of sleep apnea using a cordless portable acoustic device
Sleep apnea (SA) is characterized by recurrent cessation of breathing during sleep. The two main types of SA are obstructive sleep apnea (OSA) and central sleep apnea (CSA). OSA is the most common type and is associated with hypersomnolence that increases the risk of motor vehicle accidents [1]. OSA also increases the risk of developing cardiovascular diseases including hypertension, heart failure, and stroke [2,3], and of death from cardiovascular diseases [4]. Patients with untreated OSA consume twice as many health-care resources for treatment of cardiorespiratory diseases as subjects without OSA [5].
Source: Sleep Medicine - November 19, 2015 Category: Sleep Medicine Authors: Hisham Alshaer, Geoff R. Fernie, Wen-Hou Tseng, T. Douglas Bradley Tags: Original Article Source Type: research
Consequences of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is present in up to 25% of otherwise healthy individuals. OSA is associated with intermittent hypoxia, oxidative stress, sympathetic activation, and an inflammatory response. These perturbations mediate the role of OSA as an independent and modifiable risk factor for cardiovascular disease (CVD). OSA can induce CVD or accelerate the progression of CVD into an end-stage disorder, including heart failure and stroke. Current clinical recommendations are based on existing clinical trial data and the clinical experience of our program; current and future clinical trials will help to optimize manage...
Source: Sleep Medicine Clinics - August 17, 2016 Category: Sleep Medicine Authors: Rami Khayat, Adam Pleister Source Type: research
Sleep Duration and Midday Napping with 5-Year Incidence and Reversion of Metabolic Syndrome in Middle-Aged and Older Chinese
Conclusions:Both longer sleep duration and longer midday napping were potential risk factors for MetS incidence, and concurrently exert adverse effects on MetS reversion.Citation:Yang L, Xu Z, He M, Yang H, Li X, Min X, Zhang C, Xu C, Angileri F, Légaré S, Yuan J, Miao X, Guo H, Yao P, Wu T, Zhang X. Sleep duration and midday napping with 5-year incidence and reversion of metabolic syndrome in middle-aged and older Chinese.SLEEP 2016;39(11):1911–1918.
Source: Sleep - November 1, 2016 Category: Sleep Medicine Source Type: research
DSM-5 Insomnia and Short Sleep: Comorbidity Landscape and Racial Disparities
Conclusions:Insomnia disorder with short sleep is the most severe phenotype of insomnia and comorbid with many cardiometabolic and psychiatric illnesses, whereas morbidity profiles are highly similar between insomniacs with normal sleep duration and former insomniacs. Short sleep endemic to black Americans increases risk for the short sleep insomnia phenotype and likely contributes to racial disparities in cardiometabolic disease and psychiatric illness.Citation:Kalmbach DA, Pillai V, Arnedt JT, Drake CL. DSM-5 insomnia and short sleep: comorbidity landscape and racial disparities.SLEEP 2016;39(12):2101–2111.
Source: Sleep - December 1, 2016 Category: Sleep Medicine Source Type: research
Cognitive Dysfunction: Another reason to treat obstructive sleep apnea in stroke patients
None.
Source: Sleep Medicine - January 4, 2017 Category: Sleep Medicine Authors: Karin G. Johnson, Douglas C. Johnson Tags: Editorial Source Type: research
The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia.
CONCLUSION: Hypertension can be induced by CIH in SD rats. The CIH-induced elevation of BP is at least partially mediated via the Nox4-induced ROS/RhoA/ROCK pathway.
PMID: 28078487 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - January 10, 2017 Category: Sleep Medicine Authors: Lu W, Kang J, Hu K, Tang S, Zhou X, Xu L, Li Y, Yu S Tags: Sleep Breath Source Type: research
Stratification of cardiovascular risk in patients with atrial fibrillation and obstructive sleep apnea-validity of the 2MACE score.
CONCLUSION: OSA prevalence is increased in AF patients and is associated with an increase 2MACE score-an indicator of major cardiovascular events. There is a linear relationship between severity of OSA and increasing 2MACE scores, indicating increasing cardiovascular risk related to OSA severity.
PMID: 28155102 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 1, 2017 Category: Sleep Medicine Authors: Platek AE, Szymanski FM, Filipiak KJ, Dudzik-Plocica A, Krzowski B, Karpinski G Tags: Sleep Breath Source Type: research
Is a “gut full” of bad bugs driving metabolic disease in shift workers?
Shift workers make up a significant proportion of the total workforce in industrialised countries, with about one in five employees working during night time hours.1 There is strong epidemiological evidence that these workers are at increased risk for developing obesity, type II diabetes, coronary heart disease, stroke and cancer.2 Furthermore, obesity can contribute to worsening of other conditions that are commonly suffered by shift workers such as sleep apnoea. The mechanisms that promote obesity and metabolic disease amongst shift workers are thought to arise from an imposed chronic disruption and misalignment between ...
Source: Sleep Medicine Reviews - February 19, 2017 Category: Sleep Medicine Authors: Craig L. Phillips, Maria Comas Tags: Editorial Source Type: research
Rehabilitation of Cardiovascular Disorders and Sleep Apnea
Obstructive sleep apnea (OSA) is present in more than 50% of patients referred to cardiac rehabilitation units. However, it has been under-recognized in patients after stroke and heart failure. Those with concurrent OSA have worse clinical course. Early treatment of coexisting OSA with continuous positive airway pressure (CPAP) results in improved rehabilitation outcomes and quality of life. Possible mechanisms by which CPAP may improve recovery include decreased blood pressure fluctuations associated with apneas, and improved left ventricular function, cerebral blood flow, and oxygenation. Early screening and treatment of...
Source: Sleep Medicine Clinics - March 8, 2017 Category: Sleep Medicine Authors: Behrouz Jafari Source Type: research
Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline
Introduction:This guideline establishes clinical practice recommendations for the diagnosis of obstructive sleep apnea (OSA) in adults and is intended for use in conjunction with other American Academy of Sleep Medicine (AASM) guidelines on the evaluation and treatment of sleep-disordered breathing in adults.Methods:The AASM commissioned a task force of experts in sleep medicine. A systematic review was conducted to identify studies, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) process was used to assess the evidence. The task force developed recommendations and assigned strengths base...
Source: Journal of Clinical Sleep Medicine : JCSM - March 15, 2017 Category: Sleep Medicine Source Type: research
Diagnosing and managing sleep apnea in patients with chronic cerebrovascular disease: a randomized trial of a home-based strategy.
CONCLUSIONS: Patients with cerebrovascular disease and hypertension have a high prevalence of OSA. The use of portable polysomnography, and auto-titrating CPAP in the patients' homes, improved both the diagnosis and the treatment for sleep apnea compared with usual care but did not lower blood pressure.
PMID: 28386781 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - April 6, 2017 Category: Sleep Medicine Authors: Bravata DM, McClain V, Austin C, Ferguson J, Burrus N, Miech EJ, Matthias MS, Chumbler N, Ofner S, Foresman B, Sico J, Vaz Fragoso CA, Williams LS, Agarwal R, Concato J, Klar Yaggi H Tags: Sleep Breath Source Type: research
Sleep and the Heart: What ’s Next?
The important relationship between cardiovascular disease (CVD) and sleep medicine was recognized in the early years following the emergence of sleep medicine itself as an independent field of Medicine in the 1970s.1,2 The study of the relationship between sleep and the heart has grown exponentially over the past few decades. Although the areas of interaction between sleep and cardiovascular health are numerous, most of the focus over the past few decades has been on the relationship between sleep-disordered breathing (SDB) and heart failure or other advanced cardiovascular disorders, such as stroke and coronary disease.
Source: Sleep Medicine Clinics - May 4, 2017 Category: Sleep Medicine Authors: Rami N. Khayat Tags: Preface Source Type: research
Clarifying the Role of Hypoxia in Obstructive Sleep Apnea as a Potential Promulgator of Atrial Fibrillation in Ischemic Stroke
Source: Journal of Clinical Sleep Medicine : JCSM - May 13, 2017 Category: Sleep Medicine Source Type: research
Stereotyped episodes of aphasia and immobility: how cataplexy mimics stroke in an elderly patient
E.A.: acquisition of data, interpretation of data, drafting the manuscript, revision of the manuscript, final approval to the final version to be published.
Source: Sleep Medicine - June 19, 2017 Category: Sleep Medicine Authors: E. Antelmi, F. Pizza, S. Vandi, G. Plazzi Tags: Video-Clinical Corners Source Type: research
