The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia.

CONCLUSION: Hypertension can be induced by CIH in SD rats. The CIH-induced elevation of BP is at least partially mediated via the Nox4-induced ROS/RhoA/ROCK pathway.
PMID: 28078487 [PubMed - as supplied by publisher]

Source: Sleep and Breathing - January 10, 2017 Category: Sleep Medicine Authors: Lu W, Kang J, Hu K, Tang S, Zhou X, Xu L, Li Y, Yu S Tags: Sleep Breath Source Type: research