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Specialty: Sleep Medicine
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Total 345 results found since Jan 2013.
Obstructive sleep apnea research: challenges and new horizons
Badran et al. provide an overview of insights into obstructive sleep apnea (OSA) research with a focus on cardiovascular-specific areas including hypertension, diabetes mellitus, coronary artery disease, stroke and heart failure, and updates of the role of oxidative stress, systemic inflammation and endothelial dysfunction as intermediate pathways. A discussion on the role of experimental animal models to enhance the elucidation of underlying mechanistic pathways is also provided, particularly in terms of isolating the unique effects of specific OSA-related pathophysiologic processes including models of upper airway occlus...
Source: Sleep Medicine - April 7, 2014 Category: Sleep Medicine Authors: Reena Mehra Tags: Editorials Source Type: research
Effects of Obstructive Sleep Apnea and Obesity on Exercise Function in Children
Conclusions:Children with OSA are exercise limited due to a reduced cardiac output and VO2 peak at peak exercise capacity, independent of their weight status. Comorbid OSA can further decrease exercise performance in obese children.Citation:Evans CA, Selvadurai H, Baur LA, Waters KA. Effects of obstructive sleep apnea and obesity on exercise function in children. SLEEP 2014;37(6):1103-1110.
Source: Sleep - May 30, 2014 Category: Sleep Medicine Source Type: research
Prognostic implication of obstructive sleep apnea diagnosed by post-discharge sleep study in patients presenting with acute coronary syndrome
Conclusion: OSA diagnosed in patients treated with percutaneous coronary intervention for ACS by post-discharge sleep studies conducted 2weeks after percutaneous coronary intervention was independently associated with MACCEs at 24-month follow-up.
Source: Sleep Medicine - April 14, 2014 Category: Sleep Medicine Authors: Germaine Loo, Adeline Y. Tan, Chieh-Yang Koo, Bee-Choo Tai, Mark Richards, Chi-Hang Lee Tags: Original Articles Source Type: research
Sleep duration is associated with white matter hyperintensity volume in older adults: the Northern Manhattan Study.
In conclusion, long sleep duration was associated with a greater burden of white matter lesions in this stroke-free urban sample. The association was seen mainly among those with diabetes mellitus.
PMID: 25040435 [PubMed - as supplied by publisher]
Source: Journal of Sleep Research - July 7, 2014 Category: Sleep Medicine Authors: Ramos AR, Dong C, Rundek T, Elkind MS, Boden-Albala B, Sacco RL, Wright CB Tags: J Sleep Res Source Type: research
Diurnal and Twenty-Four-Hour Patterning of Human Diseases: Cardiac, Vascular, and Respiratory Diseases, Conditions, and Syndromes
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24-hour patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhyth...
Source: Sleep Medicine Reviews - July 18, 2014 Category: Sleep Medicine Authors: Michael H. Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C. Hermida, Ruana Tiseo, Linda L. Sackett-Lundeen, Erhard Haus Source Type: research
Restless Legs Syndrome as a First Manifestation of a Cerebral Infarct
The onset of restless legs syndrome (RLS) is usually progressive and the neural substrates underlying its pathophysiology remain to be identified. Here we report on a patient presenting with acute-onset RLS that was symptomatic of a right anteromedial pontine infarction. This case is exceptional because RLS appeared several hours before the occurrence of a regressive dysarthria clumsy-hand syndrome. Additionally, millimetric MRI sections showed that the structures possibly involved in RLS pathogenesis were the corticospinal tract, the pontine nuclei, and the pontocerebellar fibers. Although this is uncommon, clinicians sho...
Source: Journal of Clinical Sleep Medicine : JCSM - September 13, 2014 Category: Sleep Medicine Source Type: research
SOS score: an optimized score to screen acute stroke patients for obstructive sleep apnea
Source: Sleep Medicine - May 21, 2014 Category: Sleep Medicine Authors: Millene R. Camilo, Heidi H. Sander, Alan L. Eckeli, Regina M.F. Fernandes, Taiza E.G. Santos-Pontelli, Joao P. Leite, Octavio M. Pontes-Neto Source Type: research
Daytime sleepiness and risk of coronary heart disease and stroke: results from the Nurses’ Health Study II
Source: Sleep Medicine - April 11, 2014 Category: Sleep Medicine Authors: James E. Gangwisch, Kathryn Rexrode, John P. Forman, Kenneth Mukamal, Dolores Malaspina, Diane Feskanich Tags: Original Articles Source Type: research
Heart rate variability and cardiorespiratory coupling in obstructive sleep apnea: elderly compared with young
Obstructive sleep apnea (OSA) is a respiratory disorder characterized by recurrent airflow obstruction caused by total or partial collapse of the upper airways [1,2]. Aging is associated with increased apnea prevalence and is thus known to be a major factor contributing to the risk of OSA [3,4]. Moreover, elderly adults with OSA are at greater risk for cardiovascular disease (i.e. coronary artery disease, congestive heart failure, ischemic disease, and stroke) [5,6].
Source: Sleep Medicine - June 27, 2014 Category: Sleep Medicine Authors: R. Trimer, R. Cabidu, L.L.M. Sampaio, R. Stirbulov, D. Poiares, S. Guizilini, A.M. Bianchi, F.S.M. Costa, R.G. Mendes, A. Delfino, R. Arena, A. Borghi-Silva Tags: Original Article Source Type: research
Diurnal and twenty-four hour patterning of human diseases: Cardiac, vascular, and respiratory diseases, conditions, and syndromes
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhythm...
Source: Sleep Medicine Reviews - July 18, 2014 Category: Sleep Medicine Authors: Michael H. Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C. Hermida, Ruana Tiseo, Linda L. Sackett-Lundeen, Erhard L. Haus Tags: Clinical review Source Type: research
Excessive daytime somnolence and cardiovascular health: A population-based study in rural Ecuador
Publication date: Available online 16 October 2014 Source:Sleep Science Author(s): Oscar H. Del Brutto , Robertino M. Mera , Mauricio Zambrano , Pablo R. Castillo In a population-based study conducted in rural Ecuador, 635 stroke-free persons aged ≥40 years were interviewed with the Epworth sleepiness scale and screened to assess their cardiovascular health (CVH) status. Excessive daytime somnolence was present in 22% persons and a poor CVH status in 69%. In a generalized linear model after adjusting for age and sex, excessive daytime somnolence was not associated with a poor CVH status or with any of the individual me...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research
Nonparametric methods in actigraphy: An update
Publication date: Available online 29 September 2014 Source:Sleep Science Author(s): Bruno da Silva Brandão Gonçalves , Paula R.A. Cavalcanti , Gracilene R. Tavares , Tânia F. Campos , John F. Araujo Circadian rhythmicity in humans has been well studied using actigraphy, a method of measuring gross motor movement. As actigraphic technology continues to evolve, it is important for data analysis to keep pace with new variables and features. Our objective is to study the behavior of two variables, interdaily stability and intradaily variability, to describe rest activity rhythm. Simulated data and actigraphy data of huma...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research
Erectile dysfunction and obstructive sleep apnea: From mechanisms to a distinct phenotype and combined therapeutic strategies
Non-communicable Diseases (NCDs), mainly cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases, are responsible for two-thirds of the 57 million annual deaths worldwide. Tobacco smoking, physical inactivity, unhealthy diets and the resulting obesity are established risk factors for many chronic diseases (Figure 1). Management of the rise in the prevalence of chronic diseases is a major challenge facing governments and health-care systems worldwide. As these disorders are now the leading causes of death and hospitalizations, health authorities assign high priority to heart disease, diabetes, sleep apne...
Source: Sleep Medicine Reviews - December 27, 2014 Category: Sleep Medicine Authors: Jean-Louis Pépin, Renaud Tamisier, Diane Godin-Ribuot, Patrick Lévy Tags: Guest editorial Source Type: research
Can Psychomotor Vigilance Task Improve the Diagnosis of Excessive Daytime Sleepiness in Stroke Patients?
Source: Journal of Clinical Sleep Medicine : JCSM - January 14, 2015 Category: Sleep Medicine Source Type: research
Poor sleep quality and silent markers of cerebral small vessel disease: A population-based study in community-dwelling elders (The Atahualpa Project)
• Stroke and sleep disorders are increasing in many low-income and middle-income countries.• A link between both conditions has been suggested.• Reports on sleep quality and silent markers of small vessel disease are scarce.• Poor sleep quality is associated with the severity of white matter hyperintensity.• Cause and effect between both conditions must be assessed in longitudinal studies.
Source: Sleep Medicine - January 27, 2015 Category: Sleep Medicine Authors: Oscar H. Del Brutto, Robertino M. Mera, Mauricio Zambrano, Julio Lama, Victor J. Del Brutto, Pablo R. Castillo Tags: Brief Communication Source Type: research
