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Specialty: Sleep Medicine

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Total 345 results found since Jan 2013.

Sleep loss as risk factor for neurologic disorders: A review
Abstract: Sleep loss refers to sleep of shorter duration than the average baseline need of seven to eight hours per night. Sleep loss and sleep deprivation have severe effects on human health. In this article, we review the main aspects of sleep loss, taking into account its effects on the central nervous system. The neurocognitive and behavioral effects of sleep loss are well known. However, there is an increasing amount of research pointing to sleep deprivation as a risk factor for neurologic diseases, namely stroke, multiple sclerosis, Alzheimer’s disease, headache, epilepsy, pain, and somnambulism. Conversely, sleep ...
Source: Sleep Medicine - January 25, 2013 Category: Sleep Medicine Authors: Jose-Alberto Palma, Elena Urrestarazu, Jorge Iriarte Tags: Review Source Type: research

Alcohol-mediated sleep paralysis: The earliest known description
Sleep paralysis is defined as rapid eye movement parasomnia and a period of the inability to perform voluntary movements at sleep onset or upon awakening. Sleep paralysis may occur as isolated or familial forms, or as one of the classic tetrad of narcolepsy symptoms . A few factors are believed to predispose individuals to sleep paralysis including irregular sleep habits, sleep deprivation, and other disturbances of the sleep-wake rhythm, mental stress, overtiredness, and sleeping in the supine position. Comparable to the sleep paralysis, the term “Kabus” has been frequently used by the medieval Persian physicians. The...
Source: Sleep Medicine - November 5, 2012 Category: Sleep Medicine Authors: Samad E.J. Golzari, Kamyar Ghabili Tags: Letters to the Editor Source Type: research

Obstructive Sleep Apnea as a Risk Factor for Cerebral White Matter Change in a Middle-Aged and Older General Population
Conclusions:Moderate to severe OSA is an independent risk factor for WMC in middle-aged and older individuals. Thus, early recognition and treatment of OSA could reduce the risk of stroke and vascular dementia.Citation:Kim H; Yun CH; Thomas RJ; Lee SH; Seo HS; Cho ER; Lee SK; Yoon DW; Suh S; Shin C. Obstructive sleep apnea as a risk factor for cerebral white matter change in a middle-aged and older general population. SLEEP 2013;36(5):709-715.
Source: Sleep - May 4, 2013 Category: Sleep Medicine Source Type: research

Sleep Apnea Cardiovascular Clinical Trials—Current Status and Steps Forward: The International Collaboration of Sleep Apnea Cardiovascular Trialists
This article summarizes the status of clinical trials evaluating the potential cardiovascular benefits of sleep apnea treatment and discusses the challenges of conducting such trials, and introduces the International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT), a clinical research collaboration formed to foster cardiovascular sleep research.Citation:Gottlieb DJ; Craig SE; Lorenzi-Filho G; Heeley E; Redline S; McEvoy RD; Durán-Cantolla J. Sleep apnea cardiovascular clinical trials— current status and steps forward: the International Collaboration of Sleep Apnea Cardiovascular Trialists. SLE...
Source: Sleep - July 2, 2013 Category: Sleep Medicine Source Type: research

Association between Sleep Duration and the Mini-Mental Score: The Northern Manhattan Study
Conclusion:In this cross-sectional analysis among an elderly community cohort, long sleep duration was associated with worse MMSE performance.Citation:Ramos AR; Dong C; Elkind MSV; Boden-Albala B; Sacco RL; Rundek T; Wright CB. Association between Sleep Duration and the Mini-Mental Score: The Northern Manhattan Study. J Clin Sleep Med 2013;9(7):669-673.
Source: Journal of Clinical Sleep Medicine : JCSM - July 15, 2013 Category: Sleep Medicine Source Type: research

Sleep and mortality: cause, consequence, or symptom?
Epidemiologic studies of self-reported sleep and health status began to appear more than 40years ago. However, in the last 15years there has been an explosion of population science on the relationships between sleep quantity and quality as well as a variety of health outcomes, and the implications for public health have become apparent . There is sufficient evidence to support the idea that disturbances of quantity and quality of sleep, however and wherever measured, are associated with increased likelihood of developing conditions, including neurobehavioral difficulties, obesity, hypertension, diabetes mellitus, coronary ...
Source: Sleep Medicine - May 20, 2013 Category: Sleep Medicine Authors: Francesco P. Cappuccio, Michelle A. Miller Tags: Editorials Source Type: research

Beauty Sleep? Study Suggests CPAP Therapy May Lead to More Alert, Youthful, and Attractive Appearance
This study may add to the motivation of patients to find ways to make it work for them. Follow me on Twitter or Facebook to receive notice of all the latest updates to this site.Beauty Sleep? Study Suggests CPAP Therapy May Lead to More Alert, Youthful, and Attractive Appearance originally appeared on About.com Sleep Disorders on Friday, September 13th, 2013 at 12:00:49.Permalink | Comment | Email this
Source: About Sleep Disorders - September 13, 2013 Category: Sleep Medicine Source Type: news

Mortality of Patients with Obstructive Sleep Apnea in Korea
Conclusions:The present study showed that the increased mortality was also associated with the increased severity of OSA in Koreans as shown in the studies performed in the Western countries.Citation:Lee JE; Lee CH; Lee SJ; Ryu Y; Lee WH; Yoon IY; Rhee CS; Kim JW. Mortality of patients with obstructive sleep apnea in Korea. J Clin Sleep Med 2013;9(10):997-1002.
Source: Journal of Clinical Sleep Medicine : JCSM - October 16, 2013 Category: Sleep Medicine Source Type: research

Effects of Obstructive Sleep Apnea Therapy on Cardiovascular Disease
This article reviews current evidence on the impact of treatment of obstructive sleep apnea with continuous positive airway pressure on specific cardiovascular outcomes, namely, subclinical atherosclerosis (endothelial dysfunction), coronary heart disease, cardiac arrhythmias, and stroke. The scope of this article is restricted to studies that involve obstructive sleep apnea. The database PubMed was searched from 1990 to February 2013 for all relevant articles pertaining to these cardiovascular conditions and a critical review of each article was conducted. Articles with the most scientific impact are discussed.
Source: Sleep Medicine Clinics - November 12, 2013 Category: Sleep Medicine Authors: Neomi Shah, Jorge R. Kizer, H. Klar Yaggi Source Type: research

Predictors of Long-Term Adherence to Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea and Cardiovascular Disease in the SAVE Study
Conclusion:Continuous positive airway pressure use in patients with coexisting cardiovascular disease and moderate to severe obstructive sleep apnea decreases significantly over 12 months. This decline can be predicted by early patient experiences with continuous positive airway pressure (i.e., adherence and side effects at 1 month), raising the possibility that intensive early interventions could improve long-term continuous positive airway pressure compliance in this patient population.Clinical Trials Register:Clinical Trials, http://www.clinicaltrials.gov, NCT00738179.Citation:Chai-Coetzer CL; Luo YM; Antic NA; Zhang XL...
Source: Sleep - November 30, 2013 Category: Sleep Medicine Source Type: research

The effect of continuous positive airway pressure therapy on vascular function in obstructive sleep apnea: how much is enough?
Over the last two decades, obstructive sleep apnea (OSA) has emerged as a considerable public health burden. Due to the ongoing epidemic of obesity, which is strongly linked to OSA, the prevalence of the disease has been steadily rising. According to recent data from the Wisconsin Sleep Cohort, the combination of sleep-disordered breathing as indicated by an apnea–hypopnea index of>5 events per hour and excessive daytime sleepiness occurs in approximately 14% of men and 5% of women between the ages of 30 and 70years . Cardiovascular diseases (CVDs) represent the principal morbidity and mortality in OSA and large-scale ep...
Source: Sleep Medicine - November 8, 2013 Category: Sleep Medicine Authors: Silke Ryan Tags: Editorials Source Type: research

Excessive Daytime Sleepiness is Associated with Longer Culprit Lesion and Adverse Outcomes in Patients with Coronary Artery Disease
Conclusion:In patients presenting with coronary artery disease, excessive daytime sleepiness based on ESS > 10 was associated with longer culprit lesions and future adverse cardiovascular events.Citation:Lee CH; Ng WY; Hau W; Ho HH; Tai BC; Chan MY; Richards AM; Tan HC. Excessive daytime sleepiness is associated with longer culprit lesion and adverse outcomes in patients with coronary artery disease. J Clin Sleep Med 2013;9(12):1267-1272.
Source: Journal of Clinical Sleep Medicine : JCSM - December 14, 2013 Category: Sleep Medicine Source Type: research

Influence and Predicting Variables of Obstructive Sleep Apnea on Cardiac Function and Remodeling in Patients without Congestive Heart Failure
Conclusions:Patients with moderate to severe OSAS tend to have cardiac dysfunction revealed by echocardiography. High AHI in REM sleep is significantly associated with cardiovascular remodeling and ventricular diastolic dysfunction, and may be a potential variable to predict cardiac dysfunction.Citation:Chen YL; Su MC; Liu WH; Wang CC; Lin MC; Chen MC. Influence and predicting variables of obstructive sleep apnea on cardiac function and remodeling in patients without congestive heart failure. J Clin Sleep Med 2014;10(1):57-64.
Source: Journal of Clinical Sleep Medicine : JCSM - January 14, 2014 Category: Sleep Medicine Source Type: research

Circadian Variability of Fibrinolytic Markers and Endothelial Function in Patients with Obstructive Sleep Apnea
Conclusion:The presence of obstructive sleep apnea adversely affects circadian fibrinolytic balance with higher mean plasminogen activator inhibitor-1 activity and antigen, and significantly lower mean tissue-type plasminogen activator activity compared with controls. This perturbation may be an important mechanism for increased cardiovascular events in patients with obstructive sleep apnea. Intermittent hypoxia and changes in circadian clock gene activity in obstructive sleep apnea may be responsible for these findings and warrant further study. Favorable changes in fibrinolytic balance may underlie the reduction in cardi...
Source: Sleep - February 3, 2014 Category: Sleep Medicine Source Type: research

Sleep Impairment and Prognosis of Acute Myocardial Infarction: A Prospective Cohort Study
Conclusion:Results suggest sex-specific effects of impaired sleep that differ by short- and long-term prognosis. Sleep complaints are frequent, easily recognizable, and potentially manageable. Evaluation of sleep complaints may, even if they represent prognostic markers rather than risk factors, provide additional information in clinical risk assessment that could benefit secondary cardiovascular prevention.Citation:Clark A, Lange T, Hallqvist J, Jennum P, Rod NH. Sleep impairment and prognosis of acute myocardial infarction: a prospective cohort study. SLEEP 2014;37(5):851-858.
Source: Sleep - May 1, 2014 Category: Sleep Medicine Source Type: research