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Specialty: Sleep Medicine

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Total 345 results found since Jan 2013.

Relationship between obstructive sleep apnea and neuroimaging signatures of cerebral small vessel disease in community-dwelling older adults. The Atahualpa Project
/Objectives: Evidence of a relationship between obstructive sleep apnea (OSA) and neuroimaging signatures of cerebral small vessel disease (SVD) is limited. The present study aimed to evaluate this association in older adults living in rural Ecuador, where small vessel disease is a major pathogenetic mechanism underlying stroke.
Source: Sleep Medicine - June 26, 2017 Category: Sleep Medicine Authors: Oscar H. Del Brutto, Robertino M. Mera, Mauricio Zambrano, Pablo R. Castillo Source Type: research

Long sleep duration and health outcomes: A systematic review, meta-analysis and meta-regression
We examined the dose-response relationship between long sleep duration and health outcomes including mortality and the incidence of diabetes mellitus, hypertension, cardiovascular diseases, stroke, coronary heart diseases, obesity, depression and dyslipidemia. We collected data from 5,134,036 participants from 137 prospective cohort studies. For the independent variable, we categorized participants at baseline as having long sleep duration or normal sleep duration. Risk ratios (RRs) for mortality and incident health conditions during follow-up were calculated through meta-analyses of adjusted data from individual studies.
Source: Sleep Medicine Reviews - July 4, 2017 Category: Sleep Medicine Authors: Maki Jike, Osamu Itani, Norio Watanabe, Daniel J. Buysse, Yoshitaka Kaneita Tags: Clinical Review Source Type: research

Severe obstructive sleep apnea is associated with cochlear function impairment.
CONCLUSIONS: Acoustic transference function of middle ear is similar in adults with and without OSA. Severe OSA is independently associated with cochlear function impairment in patients with no significant co-morbidities. PMID: 28681146 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - July 5, 2017 Category: Sleep Medicine Authors: Matsumura E, Matas CG, Sanches SGG, Magliaro FCL, Pedreño RM, Genta PR, Lorenzi-Filho G, Carvallo RMM Tags: Sleep Breath Source Type: research

Positive Airway Pressure Therapy for Hyperventilatory Central Sleep  Apnea
Central sleep apnea (CSA) and Hunter-Cheyne-Stokes breathing (HCSB) are caused by failure of the pontomedullary pacemaker generating breathing rhythm. CSA/HCSB may complicate several disorders causing recurrent arousals and desaturations. Common causes of CSA in adults are congestive heart failure, stroke, and chronic use of opioids; opioids have hypoventilatory effects. Diagnosis and treatment of hyperventilatory CSA may improve quality of life, and, when associated with heart failure or cerebrovascular disease, reduce morbidity and perhaps mortality.
Source: Sleep Medicine Clinics - September 6, 2017 Category: Sleep Medicine Authors: Shahrokh Javaheri, Lee K. Brown Source Type: research

Distinct Patterns of Hyperpnea During Cheyne-Stokes Respiration: Implication for Cardiac Function in Patients With Heart Failure
Conclusions:Patients with HF and a negative CSR-CSA pattern have evidence of worse cardiac function than those with a positive pattern. Greater positive expiratory pressure during hyperpnea is likely generated during the negative pattern and might support stroke volume in patients with worse cardiac function.Commentary:A commentary on this article appears in this issue on page 1227.Clinical Trial Registration:The trial is registered with Current Controlled Trials (www.controlled-trials.com; ISRCTN67500535) and Clinical Trials (www.clinicaltrials.gov; NCT01128816).Citation:Perger E, Inami T, Lyons OD, Alshaer H, Smith S, Fl...
Source: Journal of Clinical Sleep Medicine : JCSM - November 14, 2017 Category: Sleep Medicine Source Type: research

Ocular Manifestations of Obstructive Sleep Apnea
Conclusions:Hypoxia induced by nightly cessation of breathing increases patients' risk of coronary artery disease, heart failure, stroke, and other conditions. As with many maladies detrimental to vascular health, obstructive sleep apnea affects the eye and ocular adnexa. This paper summarizes the current evidence implicating OSA in these ocular maladies and highlights their proposed mechanisms. The authors describe ocular pathology which sleep specialists may encounter. We encourage more aggressive attention to ocular symptoms in patients with sleep apnea to prevent vision-threatening complications. Further research shoul...
Source: Journal of Clinical Sleep Medicine : JCSM - November 14, 2017 Category: Sleep Medicine Source Type: research

Impaired cerebrovascular reactivity in obstructive sleep apnea: A case-control study
Obstructive sleep apnea (OSA) is an independent risk factor for stroke. Little is known about the cerebrovascular hemodynamic changes during apnea. Hypercapnia occurs in apneas and hypopneas, and a reduced cerebral vasodilatory response to CO2 could compromise the cerebral blood flow (CBF). Therefore, we aimed to evaluate whether the apnea −hypopnea index (AHI) affected the cerebrovascular response to CO2.
Source: Sleep Medicine - November 15, 2017 Category: Sleep Medicine Authors: Laura B. Ponsaing, Ulrich Lindberg, Egill Rostrup, Helle K. Iversen, Henrik B.W. Larsson, Poul Jennum Tags: Original Article Source Type: research

Long sleep duration and health outcomes: a systematic review, meta-analysis and meta-regression
Introduction: The dose-response of long sleep duration in mortality and the incidence of important health outcomes such as diabetes mellitus, hypertension, cardiovascular diseases, stroke, coronary heart diseases, obesity, depression and dyslipidemia has been explored.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: N. Watanabe, J. Maki, O. Itani, D. Buysse, Y. Kaneita Tags: Other Source Type: research

Objective sleep measures in subacute stroke inpatients associated with levels/improvements in activities of daily living
Introduction: We investigated if objective polysomnographic measures of prevalent sleep problems, such as sleep-disordered-breathing (SDB) and insomnia, are associated with activities of daily living levels in inpatients at rehabilitation units.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: H. Ting, R.-J. Huang Tags: Sleep Breathing Disorders Source Type: research

Cerebral hemodynamics in sleep apnea and actigraphy-determined sleep duration in a sample of the Hispanic community health study: study of Latinos
Introduction: We sought to evaluate cerebral hemodynamics in sleep apnea and actigraphy-determined short sleep duration using transcranial Doppler ultrasound (TCD) blood flow velocity in a sub-sample of Hispanics/Latinos without stroke and cardiovascular disease.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: D. Yang, T. Rundek, S. Patel, D. Cabral, S. Redline, F. Testai, J. Jianwen Cai, P. Zee, A. Ramos Tags: Other Source Type: research

An association between the risk of obstructive sleep apnea, as measured by stop-bang questionnaire and arterial hypertension in the adult population in Poland
Introduction: Obstructive sleep apnea is a common chronic medical condition strongly linked with obesity. Obstructive sleep apnea has been associated with cardiovascular morbidity such as arterial hypertension, stroke and heart failure, but the majority of these studies were done in sleep laboratory populations of predominantly male subjects. We hypothesize that obstructive sleep apnea will be associated with arterial hypertension in both genders in the general population.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: A. Nahorecki, K. Postrzech-Adamczyk, K. Zatonska, J. Lawson, M. Wolyniec, R. Skomro, A. Szuba Tags: Sleep Breathing Disorders Source Type: research

Advanced analysis of sleep spindles: from healthy to damaged brains
Introduction: Sleep spindles are one of the hallmarks of NREM sleep in the human EEG. Despite their recognisability as single events even in continuous EEG traces, they have often been measured using spectral power analysis in the 11-16  Hz range. Here we introduce an automatic detection algorithm for individual spindle events, with emphasis on its utility in high-density EEG recordings. Furthermore we demonstrate how spindle parameters could be analysed using 3 exemplary analyses: early versus late night spindles; young versus el derly spindles; and spindle properties after thalamic stroke versus age matched controls.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: A. Mensen, R. Poryazova, R. Huber, C. Bassetti Tags: Technology/Technical Source Type: research

The impact of a telemedicine monitoring on positive airway pressure in na ïve obstructive sleep apnea patients' outcomes: a randomized controlled trial
Introduction: Untreated Obstructive Sleep Apnea (OSA) can lead to high morbidity, such as reduced cognitive function and increased risk of accidents, and it is associated with diseases such as systemic arterial hypertension, metabolic syndrome, acute myocardial infarction, and stroke. Multimorbidity implies to change organization of care and follow-up.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: S. Marques, A.R. Bento, S. Monteiro, A. Gralho, F. Silva, M. Duarte, S. Mayoralas, C. Caneiras Tags: Sleep Breathing Disorders Source Type: research

Association between desaturation indices and comorbidities in patients with OSA- A cross sectional study
Introduction: Obstructive sleep apnea (OSA) is characterized by episodic, complete or partial nocturnal cessation of breathing with associated oxygen desaturation. It is also a known risk factor for systemic illnesses like hypertension, ischaemic heart disease and stroke. A major mechanism which triggers many of the systemic complications of OSA is hypoxemia which is measured in the hypopnea index component of the apnea-hypopnea index (AHI) and oxygen desaturation index. In the present study, we have attempted to find the association between various OSA indices and prevalent comorbidities among patients evaluated in Sleep Clinic.
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: A. Choudhury, U.M. Krishnaswamy, S.P. Mantha, N. Verma, P. Ramachandran, U. Devaraj, G.A. D'souza Tags: Sleep Breathing Disorders Source Type: research

OSAS severity: depending on AHI, apnoe length, ODI, SaO2 min, mean SaO2, SaO2 < 90% or < 88%, arterial PCO2 or a combination of some of these parameters?
Introduction: The association of Obstructive Sleep Apnea Syndrom (OSAS) with cardiovascular diseases as coronary heart disease (CVD), hypertension, stroke, arrhythmias, heart failure and metabolic disease as diabetes II is well documented. Results of correlations with different parameters of OSAS as Apnea-/Hypopnea-Index (AHI), Oxygen-Desaturation-Index (ODI), minimal Oxygen saturation (SaO2  min), mean Oxygensaturation (mean SaO2) or time with oxygen saturation below 90% (SaO2
Source: Sleep Medicine - December 1, 2017 Category: Sleep Medicine Authors: W. B öhning Tags: Sleep Breathing Disorders Source Type: research