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Condition: Ischemic Stroke
Procedure: Carotid Endarterectomy
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Total 922 results found since Jan 2013.
Carotid atherosclerotic disease: A systematic review of pathogenesis and management
Brain Circ. 2022 Sep 21;8(3):127-136. doi: 10.4103/bc.bc_36_22. eCollection 2022 Jul-Sep.ABSTRACTCarotid stenosis is an important contributor to ischemic stroke risk with resultant significant impact on neurological disability and death in adults and with worldwide implications. Management of carotid stenosis is impacted by whether there are associated symptoms along with the degree of stenosis. Understanding of the pathogenesis of carotid atherosclerosis or stenosis is important in management of carotid stenosis. Atherosclerotic plaque formation is a chronic insidious process with a number of potential contributors to the...
Source: Atherosclerosis - October 21, 2022 Category: Cardiology Authors: Shyamal C Bir Roger E Kelley Source Type: research
Modified Eversion Carotid Endarterectomy: A Novel Surgical Technique for Carotid Artery Stenosis Treatment
Conclusions: The mECEA is a promising surgical option for CAS with acceptable clinical outcomes. In order to prove its safety and efficacy, future practices need to be conducted by more medical workers in more large-scale trials.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Xiao Zhang Xuesong Bai Yao Feng Yinhang Zhang Renjie Yang Yutong Yang Tao Wang Ran Xu Yan Ma Liqun Jiao Source Type: research
Multivariable analysis of preoperative brain atrophy as a predictor of long-term mortality after carotid endarterectomy
CONCLUSION: Brain atrophy independently predicts long-term postoperative mortality after carotid endarterectomy in a cohort containing mainly symptomatic patients. Future studies are needed to validate the results in prospective settings and in asymptomatic patients.PMID:36209966 | DOI:10.1016/j.ejvs.2022.10.001
Source: PubMed: Eur J Vasc Endovasc ... - October 9, 2022 Category: Surgery Authors: Lauksio Iisa Wallenius Linda Lindstr öm Iisa K ärkkäinen Jussi Mikael Khan Niina Hernesniemi Jussi Protto Sara Oksala Niku Kalle Jalmari Source Type: research
Multivariable analysis of preoperative brain atrophy as a predictor of long-term mortality after carotid endarterectomy
CONCLUSION: Brain atrophy independently predicts long-term postoperative mortality after carotid endarterectomy in a cohort containing mainly symptomatic patients. Future studies are needed to validate the results in prospective settings and in asymptomatic patients.PMID:36209966 | DOI:10.1016/j.ejvs.2022.10.001
Source: PubMed: Eur J Vasc Endovasc ... - October 9, 2022 Category: Surgery Authors: Lauksio Iisa Wallenius Linda Lindstr öm Iisa K ärkkäinen Jussi Mikael Khan Niina Hernesniemi Jussi Protto Sara Oksala Niku Kalle Jalmari Source Type: research
Carotid Plaque Characteristics Predict Recurrent Ischemic Stroke and TIA: The PARISK (Plaque At RISK) Study
CONCLUSIONS: IPH and total plaque volume are independent risk factors for recurrent ipsilateral ischemic stroke or TIA in patients with mild-to-moderate carotid stenosis. These plaque characteristics improve current decision making. Validation studies to implement plaque characteristics in clinical scoring tools are needed. (PARISK: Validation of Imaging Techniques [PARISK]; NCT01208025).PMID:36202450 | DOI:10.1016/j.jcmg.2022.04.003
Source: Atherosclerosis - October 6, 2022 Category: Cardiology Authors: Dianne H K van Dam-Nolen Martine T B Truijman Anja G van der Kolk Madieke I Liem Floris H B M Schreuder Eric Boersma Mat J A P Daemen Werner H Mess Robert J van Oostenbrugge Antonius F W van der Steen Daniel Bos Peter J Koudstaal Paul J Nederkoorn Jeroen Source Type: research
Multivariable Analysis of Pre-operative Brain Atrophy as a Predictor of Long Term Mortality After Carotid Endarterectomy
Brain atrophy is associated with an increased mortality rate in elderly trauma patients and in patients treated with mechanical thrombectomy for acute ischaemic stroke. In the setting of ischaemic stroke, the association between brain atrophy and death is stronger than that of sarcopenia. It has previously been shown that lower masseter area, as a marker of sarcopenia, is linked to lower survival after carotid endarterectomy (CEA). The aim of this study was to investigate whether brain atrophy is also associated with long term mortality in patients undergoing CEA.
Source: European Journal of Vascular and Endovascular Surgery - October 6, 2022 Category: Surgery Authors: Iisa Lauksio, Linda Wallenius, Iisa Lindstr öm, Jussi M. Kärkkäinen, Niina Khan, Jussi Hernesniemi, Sara Protto, Niku K.J. Oksala Source Type: research
Multivariable analysis of preoperative brain atrophy as a predictor of long-term mortality after carotid endarterectomy
Brain atrophy is associated with increased mortality in elderly trauma patients and in patients treated with mechanical thrombectomy for acute ischemic stroke. In the setting of ischemic stroke, the association of brain atrophy with mortality is stronger than that of sarcopenia. We have previously shown that lower masseter area, as a marker of sarcopenia, is linked to lower survival after carotid endarterectomy (CEA) and hypothesized that brain atrophy would also be associated with long-term mortality in patients undergoing CEA.
Source: European Journal of Vascular and Endovascular Surgery - October 6, 2022 Category: Surgery Authors: Lauksio Iisa, Wallenius Linda, Lindstr öm Iisa, Kärkkäinen Jussi Mikael, Khan Niina, Hernesniemi Jussi, Protto Sara, Oksala Niku Kalle Jalmari Source Type: research
Perioperative Medical Management for Symptomatic Carotid Artery Interventions
AbstractPurpose of ReviewThe goal of this review is to provide the reader with an overview of symptomatic carotid stenosis and the approach to medical management of patients undergoing surgical intervention with both carotid endarterectomy (CEA) and carotid artery stenting (CAS).Recent FindingsCEA is recommended for patients with moderate to severe symptomatic carotid stenosis and transient ischemic attack (TIA) or non-disabling stroke. More recently CAS has also been shown to be a beneficial, less invasive option for patients with symptomatic carotid stenosis. All patients need urgent medical therapy to reduce the risk of...
Source: Current Treatment Options in Cardiovascular Medicine - October 1, 2022 Category: Cardiology Source Type: research
Clinical features and long-term outcomes of symptomatic low-grade carotid stenosis
CONCLUSION: Most of the symptomatic patients with low-grade stenosis had both intraplaque hemorrhage and expansive remodeling and presented a high risk of recurrence and stenosis progression. CEA may have preventive effects against ischemic events in low-grade stenosis.PMID:36179612 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106779
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Yoshitaka Kurosaki Masanori Kinosada Hiroyuki Ikeda Haruki Yamashita Kazumichi Yoshida Masaki Chin Source Type: research
Neurocritical Care Aspects of Ischemic Stroke Management
This article reviews the care of patients with ischemic stroke in the intensive care unit, including early general critical care interventions for airway control blood pressure goals according to the type of acute stroke treatment, poststroke cerebral edema management, hemorrhagic conversion in ischemic stroke, fibrinolytic reversal, and management of carotid endarterectomy and infective endocarditis. The importance of preventing common intensive care complications is discussed, including aspiration pneumonia, deep venous thrombosis, urinary tract infections, cardiac arrhythmias, and hyperglycemia.
Source: Critical Care Clinics - September 30, 2022 Category: Intensive Care Authors: Dania Qaryouti, Diana Greene-Chandos Source Type: research
Modifiable risk factors for occurrence of ipsilateral ischemic events after carotid endarterectomy beyond perioperative period
The purpose of this study was to quantify the effects of several modifiable variables on the occurrence of stroke after the initial perioperative period for patients who had undergone carotid endarterectomy (CEA).
Source: Journal of Vascular Surgery - September 28, 2022 Category: Surgery Authors: Matthew Blecha, Matthew DeJong, Janice Nam, Ashley Penton Source Type: research
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
To the Editor In a recent study of the clinical outcomes of 3737 adults with asymptomatic severe carotid stenosis who did not undergo carotid revascularization, the 5-year ipsilateral stroke rate was 4.7%. The authors concluded that “these findings may inform decision-making regarding surgical and medical treatment for patients with asymptomatic severe carotid artery stenosis.” A multicenter randomized prospective trial from 2021 reported similar 5-year stroke rates for 3625 patients with asymptomatic severe carotid stenosi s who underwent carotid endarterectomy. Based on these studies, one could come to the conclusion...
Source: JAMA - September 27, 2022 Category: General Medicine Source Type: research
Perioperative Medical Management for Symptomatic Carotid Artery Interventions
AbstractPurpose of ReviewThe goal of this review is to provide the reader with an overview of symptomatic carotid stenosis and the approach to medical management of patients undergoing surgical intervention with both carotid endarterectomy (CEA) and carotid artery stenting (CAS).Recent FindingsCEA is recommended for patients with moderate to severe symptomatic carotid stenosis and transient ischemic attack (TIA) or non-disabling stroke. More recently CAS has also been shown to be a beneficial, less invasive option for patients with symptomatic carotid stenosis. All patients need urgent medical therapy to reduce the risk of...
Source: Current Treatment Options in Cardiovascular Medicine - September 9, 2022 Category: Cardiology Source Type: research
Immunohistochemical analysis of MMP-9 and COX-2 expression in carotid atherosclerotic plaques among patients undergoing carotid endarterectomy: A prospective study
Atherosclerotic disease of the internal carotid artery is the most common cause of ischemic stroke making it the second commonest cause of death; therefore, the benefit of carotid endarterectomy (CEA) in both symptomatic and asymptomatic patients has been demonstrated by several randomized trials.1-3 Several studies highlighted that carotid atherosclerotic plaque remodelling can be partially mediated by matrix metalloproteinases (MMPs).4-7 Increased activity of MMPs can contribute to the degradation of collagen within the fibrous cap, making the cap thinner, more vulnerable and prone to rupture.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2022 Category: Neurology Authors: Davorin Sef, Miljenko Kovacevic, Bojan Jernej, Karlo Novacic, Marko Slavica, Jelka Petrak, Igor Medved, Milan Milosevic Source Type: research
