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Condition: Ischemic Stroke
Procedure: Carotid Endarterectomy

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Total 922 results found since Jan 2013.

Timing of Carotid Revascularization Procedures After Ischemic Stroke Brief Report
Background and Purpose—In 2006, the American Heart Association recommended that carotid revascularization generally occurs within 2 weeks of stroke based on data from 2 trials of carotid endarterectomy (CEA). We aimed to determine whether the time between stroke and CEA or carotid artery stenting (CAS) has decreased and whether the proportion of procedures occurring within 14 days has increased.Methods—Using validated International Classification of Diseases, Ninth Revision, Clinical Modification codes and administrative claims data from nonfederal hospitals in CA, FL, and NY, we identified patients with ischemic strok...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Michael Reznik, Hooman Kamel, Gino Gialdini, Ankur Pandya, Babak B. Navi, Ajay Gupta Tags: Secondary Prevention, Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Symptomatic Carotid Atherosclerotic Disease: Correlations Between Plaque Composition and Ipsilateral Stroke Risk Clinical Sciences
Conclusions— Features of the vulnerable carotid plaque, including plaque thrombus, low fibrous content, macrophage infiltration, and microvessel density, correlate with predicted stroke risk. This study provides a basis for plaque imaging studies focused on stroke risk stratification.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Howard, D. P. J., van Lammeren, G. W., Rothwell, P. M., Redgrave, J. N., Moll, F. L., de Vries, J.-P. P. M., de Kleijn, D. P. V., den Ruijter, H. M., de Borst, G. J., Pasterkamp, G. Tags: Pathophysiology, Carotid Stenosis, Primary and Secondary Stroke Prevention, Carotid endarterectomy Clinical Sciences Source Type: research

Residual High-Grade Stenosis After Recanalization of Extracranial Carotid Occlusion in Acute Ischemic Stroke Clinical Sciences
Conclusions— A residual high-grade stenosis of the extracranial ICA occurs in 1 of 6 patients with a symptomatic occlusion in the acute stage of cerebral ischemia. Because this may have implications for secondary prevention, we recommend follow-up imaging in these patients within a week after the event. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00880113.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Luitse, M. J. A., Velthuis, B. K., Dauwan, M., Dankbaar, J. W., Biessels, G. J., Kappelle, L. J., on behalf of the Dutch Acute Stroke Study Group, Majoie, Roos, Duijm, Keizer, van der Lugt, Dippel, Droogh-de Greve, Bienfait, van Walderveen, Wermer, Lyckla Tags: CT and MRI, Acute Cerebral Infarction, Carotid Stenosis Clinical Sciences Source Type: research

Plaque Inflammation and Unstable Morphology Are Associated With Early Stroke Recurrence in Symptomatic Carotid Stenosis Clinical Sciences
Conclusions— Plaque inflammation and other vulnerability features were associated with highest risk of stroke recurrence and may represent therapeutic targets for future stroke prevention trials.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Marnane, M., Prendeville, S., McDonnell, C., Noone, I., Barry, M., Crowe, M., Mulligan, N., Kelly, P. J. Tags: Pathophysiology Clinical Sciences Source Type: research

Early Carotid Revascularization Reduces Readmission for Recurrent Ischemic Stroke in Acute Ischemic Stroke Patients: Analysis of United States Nationwide Readmissions Database (P4.294)
Conclusions:Patients with ischemic stroke undergoing carotid revascularization during the initial hospitalization have significantly lower risk of readmission related to another ischemic strokeDisclosure: Dr. Chaudhry has nothing to disclose. Dr. Gheith has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. Riaz has nothing to disclose. Dr. Sachdeva has nothing to disclose. Dr. Sattar has nothing to disclose. Dr. Razak has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chaudhry, S., Gheith, T., Gu, S., Afzal, M.-R., Rahman, H., Riaz, A., Sachdeva, G., Sattar, A., Razak, A., Qureshi, A. Tags: In-Hospital Stroke Care Source Type: research

Long-Term Outcome After Carotid Artery Stenting: A Population-Based Matched Cohort Study Clinical Sciences
Conclusions— In this nationwide cohort study, CAS was associated with an increased long-term risk of ipsilateral stroke and death during after the perioperative phase when compared with CEA.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Jonsson, M., Lindstrom, D., Gillgren, P., Wanhainen, A., Malmstedt, J. Tags: Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke, Stenosis, Vascular Disease Clinical Sciences Source Type: research

CYP2C19 Loss-of-Function Associated with First-Time Ischemic Stroke in Non-surgical Asymptomatic Carotid Artery Stenosis During Clopidogrel Therapy
This study measures effect ofCYP2C19 genotype on ischemic stroke risk during clopidogrel therapy for asymptomatic, extracranial carotid stenosis patients. Using deidentified electronic health records, patients were selected for retrospective cohort using administrative code for carotid stenosis, availability ofCYP2C19 genotype result, clopidogrel exposure, and established patient care. Patients with intracranial atherosclerosis, aneurysm, arteriovenous malformation, prior ischemic stroke, or observation time<1 month were excluded. Dual antiplatelet therapy patients were included. Patients with carotid endarterectomy or ...
Source: Translational Stroke Research - February 21, 2021 Category: Neurology Source Type: research

Short Time Interval Between Neurologic Event and Carotid Surgery Is Not Associated With an Increased Procedural Risk Clinical Sciences
Conclusions—The time interval between the index event and carotid endarterectomy was not associated with the risk of any in-hospital stroke or death in patients with symptomatic carotid stenosis in Germany. In clinically stable patients, carotid endarterectomy might, therefore, be performed safely as soon as possible after the neurological index event.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Tsantilas, P., Kuehnl, A., Konig, T., Breitkreuz, T., Kallmayer, M., Knappich, C., Schmid, S., Storck, M., Zimmermann, A., Eckstein, H.–H. Tags: Complications, Quality and Outcomes, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Age and the fuzzy edges of embolic stroke of undetermined source: Implications for trials
After an acute ischemic stroke, clinicians pursue further diagnostic assessment to identify the most plausible causes and tailor secondary prevention strategies. Available treatments with a high level of evidence for reducing recurrence stroke risk might include long-term oral anticoagulation in patients with a major-risk cardioembolic source (atrial fibrillation, prosthetic valves, etc), carotid endarterectomy in minor ischemic stroke related to moderate to severe internal carotid artery atherosclerotic stenosis, and best-practice medical management in those with lacunar stroke due to cerebral small vessel disease.1 Howev...
Source: Neurology - August 7, 2017 Category: Neurology Authors: Charidimou, A. Tags: Stroke in young adults, All Clinical trials, All Cerebrovascular disease/Stroke, Embolism, Infarction EDITORIALS Source Type: research

Reducing Delay of Carotid Endarterectomy in Acute Ischemic Stroke Patients: A Nationwide Initiative Clinical Sciences
Conclusions— Establishing time limits of 4 days to ultrasound examination of the carotids and of 2 weeks to CEA from onset of stroke followed by a systematic multidisciplinary monitoring and auditing of processes was associated with a substantial increase in the proportion of acute ischemic stroke patients who undergo CEA within 2 weeks in Denmark.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Witt, A. H., Johnsen, S. P., Jensen, L. P., Hansen, A. K., Hundborg, H. H., Andersen, G. Tags: Carotid Stenosis, Carotid endarterectomy Clinical Sciences Source Type: research

Recurrent stroke in symptomatic carotid stenosis awaiting revascularization: A pooled analysis
Conclusions: We found high risk of recurrent ipsilateral ischemic events within the 14-day time period currently recommended for CEA. Randomized trials are needed to determine the benefits and safety of urgent vs subacute carotid revascularization within 14 days after symptom onset.
Source: Neurology - February 8, 2016 Category: Neurology Authors: Johansson, E., Cuadrado-Godia, E., Hayden, D., Bjellerup, J., Ois, A., Roquer, J., Wester, P., Kelly, P. J. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Outcomes After Acute Ischemic Stroke in the United States: Does Residential ZIP Code Matter? Stroke
Conclusions Patients from lower-income quartiles had decreased reperfusion on the first admission day, compared with patients from higher-income quartiles. The cost of hospitalization of patients from higher-income quartiles was significantly higher than that of patients from lowest-income quartiles, despite longer hospital stays in the latter group. This might be partially attributable to a lower use of key procedures among patients from lowest-income quartile.
Source: JAHA:Journal of the American Heart Association - March 15, 2015 Category: Cardiology Authors: Agarwal, S., Menon, V., Jaber, W. A. Tags: Stroke Source Type: research

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting Clinical Sciences
Background and Purpose—After carotid endarterectomy (CEA) or carotid artery stenting (CAS) in patients with transient ischemic attack or minor ischemic stroke, recurrent stroke risk falls to a low rate on modern medical treatment.Methods—We used data from 4583 patients with recent transient ischemic attack or minor stroke enrolled in the TIAregistry.org to perform a nested case–control analysis to evaluate pre- and post-CEA/CAS risk. Cases were defined as patients with a CEA/CAS during the 1-year follow-up period. For each case, 2 controls with a follow-up time greater than the time from qualifying event to CEA/CAS w...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Cristina Hobeanu, Philippa C. Lavallee, Peter M. Rothwell, Leila Sissani, Gregory W. Albers, Natan M. Bornstein, Louis R. Caplan, Geoffrey A. Donnan, Jose M. Ferro, Michael G. Hennerici, Julien Labreuche, Carlos Molina, Philippe Gabriel Steg, Pierre&ndash Tags: Secondary Prevention, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Histological Features of Carotid Plaque in Patients With Ocular Ischemia Versus Cerebral Events Clinical Sciences
Conclusions— Carotid plaques from patients undergoing endarterectomy for previous ocular ischemic events have fewer vulnerable plaque features than those from patients with recent cerebral ischemic events, possibly explaining some of the differences in risk of stroke between these groups.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Howard, D. P. J., van Lammeren, G. W., Redgrave, J. N., Moll, F. L., de Vries, J.-P. P. M., de Kleijn, D. P. V., de Borst, G. J., Pasterkamp, G., Rothwell, P. M. Tags: Pathophysiology, Imaging, Carotid Stenosis, Pathology of Stroke, Carotid endarterectomy, Other Vascular biology Clinical Sciences Source Type: research

Aggressive Medical Therapy Alone Is Not Adequate in Certain Patients With Severe Symptomatic Carotid Stenosis Controversies in Stroke
Source: Stroke - September 23, 2013 Category: Neurology Authors: Brown, M. M. Tags: Secondary prevention, Carotid Stenosis, Other Stroke Treatment - Medical, Carotid endarterectomy, Transient Ischemic Attacks Controversies in Stroke Source Type: research