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Condition: Ischemic Stroke
Procedure: Carotid Endarterectomy

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Total 922 results found since Jan 2013.

Prediction of recanalization in acute stroke patients receiving intravenous and endovascular revascularization therapy
ConclusionThe overall likelihood of recanalization was the highest in the endovascular group, and higher for intravenous thrombolysis compared with no revascularization therapy. However, our statistical models of recanalization for each individual patient indicate significant variability between treatment options, suggesting the need to include this prediction in the personalized treatment selection.
Source: International Journal of Stroke - June 30, 2014 Category: Neurology Authors: Guangming Zhu, Patrik Michel, Tudor Jovin, James T. Patrie, Wenjun Xin, Ashraf Eskandari, Weiwei Zhang, Max Wintermark Tags: Research Source Type: research

Registry Report on Kinetics of Rescue Antiplatelet Treatment to Abolish Cerebral Microemboli After Carotid Endarterectomy Brief Reports
Conclusions— These findings suggest that transcranial Doppler-directed tirofiban therapy is more effective than dextran-40 in suppression of cerebral microemboli after carotid endarterectomy.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Saedon, M., Singer, D. R. J., Pang, R., Tiivas, C., Hutchinson, C. E., Imray, C. H. E. Tags: Platelet function inhibitors, Acute Stroke Syndromes, Carotid Stenosis, Doppler ultrasound, Transcranial Doppler etc., Antiplatelets, Carotid endarterectomy, Transient Ischemic Attacks Brief Reports Source Type: research

Sex Differences in Revascularization Interventions after Acute Ischemic Stroke
Conclusions: Over the last decade, women hospitalized for AIS in the United States were less likely than men to receive cerebrovascular and cardiac reperfusion therapies. However, the IV tPA treatment sex disparity may have been eliminated.
Source: Journal of Stroke and Cerebrovascular Diseases - May 8, 2013 Category: Neurology Authors: Amytis Towfighi, Daniela Markovic, Bruce Ovbiagele Tags: Original Articles Source Type: research

Sex Differences in the Presentation, Care, and Outcomes of Transient Ischemic Attack: Results From the Ontario Stroke Registry Brief Reports
Conclusions— We found only minor sex differences in the presentation and management of transient ischemic attack, suggesting that current public awareness campaigns focusing on classic warning signs are appropriate for both women and men. Future work should focus on evaluating whether lower rates of carotid imaging, endarterectomy, and lipid-lowering therapy in women reflect undertreatment of women or are appropriate based on patient eligibility.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Li, O. L., Silver, F. L., Lichtman, J., Fang, J., Stamplecoski, M., Wengle, R. S., Kapral, M. K. Tags: Epidemiology, Secondary Prevention, Compliance/Adherence, Quality and Outcomes Brief Reports Source Type: research

18F-Fluoride and 18F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case-Control Study Molecular Imaging
Conclusions— 18F-Fluoride PET/CT highlights culprit and phenotypically high-risk carotid plaque. This has the potential to improve risk stratification and selection of patients who may benefit from intervention.
Source: Circulation: Cardiovascular Imaging - March 14, 2017 Category: Radiology Authors: Vesey, A. T., Jenkins, W. S. A., Irkle,, A., Moss, A., Sng,, G., Forsythe, R. O., Clark, T., Roberts, G., Fletcher, A., Lucatelli, C., Rudd, J. H. F., Davenport,, A. P., Mills, N. L., Al-Shahi Salman, R., Dennis, M., Whiteley, W. N., van Beek, E. J. R., D Tags: Translational Studies, Imaging, Nuclear Cardiology and PET, Cerebrovascular Disease/Stroke, Atherosclerosis Molecular Imaging Source Type: research

Vascular Anatomy Predicts the Risk of Cerebral Ischemia in Patients Randomized to Carotid Stenting Versus Endarterectomy Clinical Sciences
Background and Purpose—Complex vascular anatomy might increase the risk of procedural stroke during carotid artery stenting (CAS). Randomized controlled trial evidence that vascular anatomy should inform the choice between CAS and carotid endarterectomy (CEA) has been lacking.Methods—One-hundred eighty-four patients with symptomatic internal carotid artery stenosis who were randomly assigned to CAS or CEA in the ICSS (International Carotid Stenting Study) underwent magnetic resonance (n=126) or computed tomographic angiography (n=58) at baseline and brain magnetic resonance imaging before and after treatment. We invest...
Source: Stroke - April 24, 2017 Category: Neurology Authors: Mandy D. Muller, Frank J. Ahlhelm, Alexander von Hessling, David Doig, Paul J. Nederkoorn, Sumaira Macdonald, Philippe A. Lyrer, Aad van der Lugt, Jeroen Hendrikse, Christoph Stippich, H. Bart van der Worp, Toby Richards, Martin M. Brown, Stefan T. Engelt Tags: Magnetic Resonance Imaging (MRI), Revascularization, Stent, Cerebrovascular Disease/Stroke, Stenosis Original Contributions Source Type: research

Open Heart Surgery Does Not Increase the Incidence of Ipsilateral Ischemic Stroke in Patients with Asymptomatic Severe Carotid Stenosis
We evaluated the incidence of perioperative stroke following the institution's 2007 practice change of discontinuing combined carotid endarterectomy and open heart surgery (OHS) for patients with severe carotid stenosis.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2017 Category: Neurology Authors: John E. Castaldo, Hussam A. Yacoub, Yuebing Li, Hope Kincaid, Donna Jenny Source Type: research

Factors Associated With Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial Clinical Sciences
Conclusions—Overall, selection of sites with high enrollment rates will likely require customization to align the sites selected to the factor under study in the trial.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02089217.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Bart M. Demaerschalk, Robert D. Brown Jr, Gary S. Roubin, Virginia J. Howard, Eldina Cesko, Kevin M. Barrett, Mary E. Longbottom, Jenifer H. Voeks, Seemant Chaturvedi, Thomas G. Brott, Brajesh K. Lal, James F. Meschia, George Howard Tags: Stent, Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Factors associated with delay to carotid endarterectomy for acute ischaemic stroke in South Australia: A multicentre retrospective cohort study
The greatest benefits of carotid endarterectomy (CEA) accrue when performed within two weeks of acute ischaemic stroke (AIS) due to symptomatic carotid stenosis. Previous studies have identified multiple factors contributing to CEA delay.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2022 Category: Neurology Authors: Rudy Goh, Stephen Bacchi, Joshua G. Kovoor, Aashray K. Gupta, Minh-Son To, Christopher D. Ovenden, Joseph Dawson, Wilson Vallat, David Schultz, Jim Jannes, Timothy Kleinig Source Type: research

Remote pre-procedural ischemic stroke was the strongest risk for stroke and death associated with carotid stenting. A single center experience.
CONCLUSIONS: In our experience all patients with remote pre-procedural any territory ischemic stroke belong to risky subgroup for periprocedural stroke death after CAS. All asymptomatic patients with remote ischemic stroke should not be treated with CAS. Remote ischemic stroke increases all-cause mortality in long-term follow-up after carotid stenting. Patients ≥ 75 years also have increased risk of periprocedural stroke and death after CAS. These factors should help us to be more selective when planning carotid procedures. PMID: 27905692 [PubMed - as supplied by publisher]
Source: International Angiology - December 4, 2016 Category: Cardiology Tags: Int Angiol Source Type: research

Stroke prevention.
Abstract Patients who have had a stroke are at high risk for recurrent stroke, myocardial infarction, and vascular death. Prevention of these events should be initiated promptly after stroke, because many recurrent events occur early, and should be tailored to the precise cause of stroke, which may require specific treatment. Lifestyle advice including abstinence from smoking, regular exercise, Mediterranean-style diet, and reduction of salt intake and alcohol consumption are recommended for all patients with stroke. For most patients with ischemic stroke or TIA, control of risk factors, including lowering blood p...
Source: Presse Medicale - November 1, 2016 Category: Journals (General) Authors: Isabel C, Calvet D, Mas JL Tags: Presse Med Source Type: research

Reduction in Early Stroke Risk in Carotid Stenosis With Transient Ischemic Attack Associated With Statin Treatment
In patients with acute symptomatic carotid stenosis, statin pretreatment is associated with reduced stroke risk. Carotid endarterectomy (CEA) in patients with associated symptoms is highly effective for secondary stroke prevention. Maximum benefit appears to be in those who undergo surgery ≤2 weeks of symptom onset; however, the safety of very early CEA has been questioned. Data from the Swedish Vascular Registry indicated an 11.5% stroke and death rate in patients undergoing CEA ≤48 hours of symptom onset. This is a fourfold increase in the odds of a poor outcome compared with those undergoing CEA from 3 to 7 days (S...
Source: Journal of Vascular Surgery - January 24, 2014 Category: Surgery Authors: Á. Merwick, G.W. Albers, E.M. Arsava Tags: Abstracts Source Type: research

Technical improvements in carotid revascularization based on the mechanism of procedural stroke.
In conclusion, this review provides an overview of the pathophysiological mechanism of stroke following carotid revascularization (both CAS and CEA) and of the technical improvements that have contributed to reducing this stroke risk. PMID: 30827087 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - February 28, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Fassaert LM, de Borst GJ Tags: J Cardiovasc Surg (Torino) Source Type: research

Carotid endarterectomy during the acute period of ischemic stroke
Conclusions Urgent CEA is indicated in patients with unstable neurological symptoms as well as for those with unstable atherosclerotic plaques. Considering a high risk of stroke recurrence within the first 14 days urgent CEA is effective in the prevention of recurrent stroke. Only 2.2% patients developed postoperatively stroke.
Source: Cor et Vasa - June 10, 2017 Category: Cardiology Source Type: research

Carotid Artery Stent Placement and Carotid Endarterectomy: A Challenge for Urgent Treatment after Stroke —Early and 12-Month Outcomes in a Comprehensive Stroke Center
Conclusions CAS placement and CEA seem to offer early safe and feasible secondary stroke prevention treatments in experienced centers, even after major atherosclerotic stroke.
Source: Journal of Vascular and Interventional Radiology - June 21, 2018 Category: Radiology Source Type: research