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Condition: Ischemic Stroke
Procedure: Carotid Endarterectomy
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Total 922 results found since Jan 2013.
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis
AbstractEndoplasmic reticulum (ER) stress is an important process during the progression of atherosclerosis. The aim of this study was to elucidate the association of ER stress and clinical instability of carotid plaque. One hundred ninety-three patients with carotid stenosis undergoing carotid endarterectomies (CEAs) were enrolled. We classified the patients into 3 groups: the asymptomatic, symptomatic, and cTIA (crescendo transient ischemic attack)/SIE (stroke in evolution) groups. Immunohistological staining was performed to assess ER stress and apoptosis. The correlation between ER stress marker expression and clinical...
Source: Translational Stroke Research - November 16, 2021 Category: Neurology Source Type: research
Carotid Endarterectomy After Intracranial Endovascular Thrombectomy for Acute Ischaemic Stroke in Patients with Carotid Artery Stenosis
Recent randomised controlled trials demonstrated the benefit of intracranial endovascular thrombectomy (EVT) in acute ischaemic stroke. There is no consensus, however, on how to treat concomitant extracranial carotid artery stenosis after EVT. The aim of this study was to evaluate the outcome in patients treated with carotid endarterectomy (CEA) after EVT, comparing complication rates among patients undergoing CEA for stroke without previous EVT.
Source: European Journal of Vascular and Endovascular Surgery - December 6, 2021 Category: Surgery Authors: Magnus Jonsson, Ellinoora Aro, Katarina Bj örses, Staffan Holmin, Petra Ijäs, Nicolas Martinez-Majander, Pirkka Vikatmaa, Carl-Magnus Wahlgren, Maarit Venermo, Martin Björck Source Type: research
Effectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial
This study has been approved by the National Ethics Committee (IDRCB:2019-A01543-54/SI:19.06.21.40640). ClinicalTrials.gov NCT04053166.PMID:35164816 | DOI:10.1186/s13063-022-06061-x
Source: Atherosclerosis - February 15, 2022 Category: Cardiology Authors: Mathilde Mura Emeraude Rivoire Leila Dehina-Khenniche Mich èle Weiss-Gayet B énédicte Chazaud Camille Faes Philippe Connes Anne Long Chantal L Rytz Pauline Mury Lidia Delrieu Etienne Gouraud Marine Bordet Nellie Della Schiava Patrick Lermusiaux Matthie Source Type: research
National Institutes of Health stroke scale score at admission can predict functional outcomes in patients with ischemic stroke undergoing carotid endarterectomy
The aim of present study was to evaluate the prognostic effect of the National Institutes of Health stroke scale (NIHSS) score for patients who had undergone acute carotid endarterectomy (CEA) and assess the clinical and morphologic factors that could predict for worse outcomes.
Source: Journal of Vascular Surgery - December 23, 2021 Category: Surgery Authors: Davide Mastrorilli, Luca Mezzetto, Mario D'Oria, Roberta Fiorini, Sandro Lepidi, Lorenzo Scorsone, Edoardo Veraldi, Gian Franco Veraldi Source Type: research
Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
To the Editor In a recent study of the clinical outcomes of 3737 adults with asymptomatic severe carotid stenosis who did not undergo carotid revascularization, the 5-year ipsilateral stroke rate was 4.7%. The authors concluded that “these findings may inform decision-making regarding surgical and medical treatment for patients with asymptomatic severe carotid artery stenosis.” A multicenter randomized prospective trial from 2021 reported similar 5-year stroke rates for 3625 patients with asymptomatic severe carotid stenosi s who underwent carotid endarterectomy. Based on these studies, one could come to the conclusion...
Source: JAMA - September 27, 2022 Category: General Medicine Source Type: research
Cost-effectiveness of carotid artery stenting vs endarterectomy: A simulation
Clinical trials conducted before the introduction of modern medical management to prevent stroke demonstrated that carotid endarterectomy (CEA) and carotid artery stenting (CAS) prevent stroke following transient ischemic attack (TIA). We compared the cost-effectiveness of CEA, CAS, and modern medical management in two secular settings of medical management in individuals with incident TIA and type 2 diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2022 Category: Neurology Authors: Deanna J. Marriott, Shihchen Kuo, Wen Ye, Deborah A. Levine, William H. Herman Source Type: research
The Impact of Full Collapse on the Risk of Ischaemic Stroke in Patients with Carotid Near Occlusion
Carotid near occlusion (CNO) is a severe carotid stenosis associated with a reduction in the calibre of the extracranial internal carotid artery distal to the stenosis.1 The risk of ipsilateral stroke in patients with CNO is a controversial issue. While a post hoc analysis of the North American Symptomatic Carotid Endarterectomy Trial (NASCET) and the European Carotid Surgery Trial (ECST) reported a lower risk of ipsilateral stroke for medically treated patients with CNO compared with patients with severe (70 –99%) carotid stenosis2, more recent studies have shown that the CNO recurrence rate may be higher.
Source: European Journal of Vascular and Endovascular Surgery - April 20, 2023 Category: Surgery Authors: Andr és García-Pastor, Ana Iglesias-Mohedano, Antonio Gil-Núñez Tags: Editorial Source Type: research
Todd's paralysis due to hyperperfusion syndrome after carotid endarterectomy mimicking postoperative stroke
J Cardiovasc Surg (Torino). 2023 Jun 19. doi: 10.23736/S0021-9509.23.12720-0. Online ahead of print.ABSTRACTTodd's paralysis is a neurological deficit that is observed in <10% of patients following epileptic seizures. Cerebral hyperperfusion syndrome (CHS) is a rare complication following carotid endarterectomy (CEA), seen in 0-3% of the patients, characterized by focal neurological deficit, headache, disorientation, and sometimes seizures. In this case report, we present a case of CHS after CEA followed by seizures and Todd's paralysis that mimicked postoperative stroke. A 75-year-old female patient was admitted for CE...
Source: The Journal of Cardiovascular Surgery - June 19, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Slobodan Tanaskovic Nikola Cimbaljevic Jovan Petrovic Enes Ljatifi Mirjana Antonijevic Maja Neskovic Aleksandra Ostojic Nenad Ilijevski Source Type: research
