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12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace. No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news

NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies. (GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

A Copernican Approach to Brain Advancement: The Paradigm of Allostatic Orchestration
The objective of this presentation is to explore historical, scientific, interventional, and other differences between the two paradigms, so that innovators, researchers, practitioners, policy-makers, patients, end-users, and others can gain clarity with respect to both the explicit and implicit assumptions associated with brain advancement agendas of any kind. Over the course of three decades, a series of brain-centric, evolution-inspired insights have been articulated with increasing refinement, as principles of allostasis (Sterling and Eyer, 1988; Sterling, 2004, 2012, 2014). Allostasis recognizes that the role of the ...
Source: Frontiers in Human Neuroscience - April 25, 2019 Category: Neuroscience Source Type: research

Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy
Conclusion This proof-of-principle study evaluated the influence of cathodal contralesional tDCS on corticospinal excitability in pediatric participants with UCP. A hypothesized decrease in contralesional excitability was noted in participants in the Active+CIMT group, however, the efficacy of tDCS to modulate corticospinal excitability was not statistically different than the Sham+CIMT group. A more detailed understanding of how tDCS impacts M1 neurophysiology will be essential to inform future clinical trials on the optimal dosing parameters, based on individual brain circuitry, to explore the potential functional benef...
Source: Frontiers in Human Neuroscience - April 23, 2019 Category: Neuroscience Source Type: research

Application of Muse Cell Therapy to Stroke.
Authors: Niizuma K, Borlongan CV, Tominaga T Abstract Stroke is defined as a sudden onset of neurologic deficits arising from cerebrovascular complications. It is the second common cause of death around the world and the major cause of disability. Because brain is an organ with complicated neural networks and neurons are highly differentiated, it has been traditionally considered to possess a limited potential for regeneration. The number of stroke patients is increasing, and stroke represents a serious problem from the viewpoint of the national medical economy. Even with the current sophisticated treatments, more ...
Source: Advances in Experimental Medicine and Biology - November 30, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

Meet the Chinese Lumberjack Who Slept With an Alien
"If you can't find me," Meng Zhaoguo said over a cell phone whose signal faded from its isolation, "Just head to the last house on the logging commune lane. Or ask anyone who's around." Everyone knows the first Chinese person to allegedly be abducted by aliens. With its surging economy, China is summiting once-unseen heights in world rankings: millions of English speakers, almost the most millionaires and actually the least frugal tourists. Yet despite being slightly larger in area than the United States with four times as many people, China trails far behind when it comes to visitors from outer space. To date, only one C...
Source: Science - The Huffington Post - April 7, 2015 Category: Science Source Type: news

Test-Retest Reliability of Portable Metabolic Monitoring After Disabling Stroke
Conclusions. Our results strongly support the reliability of the K4b2 for quantifying overground gait efficiency after stroke. Use of this device may enable researchers to study how varying poststroke rehabilitation interventions affect this central measure of health and function.
Source: Neurorehabilitation and Neural Repair - October 7, 2013 Category: Neurology Authors: Stookey, A. D., McCusker, M. G., Sorkin, J. D., Katzel, L. I., Shaughnessy, M., Macko, R. F., Ivey, F. M. Tags: Clinical Research Articles Source Type: research