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Total 4990 results found since Jan 2013.

Prevalence of atrial septal defects and patent foramen ovale in a cohort of sudden cardiac death patients undergoing autopsy
CONCLUSIONS: The combined rate of PFO and ASD in a cohort of 517 patients undergoing autopsy was 7.9 %. None of these patients had experienced a cerebrovascular accident. This rate of PFOs appears lower than earlier reports and raises the possibility that the relative risk of an associated stroke could be higher than previously estimated.PMID:37734655 | DOI:10.1016/j.jjcc.2023.09.006
Source: Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Louise Fahy Stephanie Rowe Ziad Nehme Dion Stub Dominica Zentner Paul James Andreas Pflaumer Vanessa Connell Christopher Semsarian Jodie Ingles Andre La Gerche Elizabeth D Paratz Source Type: research

Global trends and hotspots in research on acupuncture for stroke: a bibliometric and visualization analysis
This study aimed to characterize the global publications and analyze the trends of acupuncture for stroke in the past 40  years. We identified 1157 publications from the Web of Science Core Collection. The number of publications grew slowly in the first three decades from 1980 until it started to grow after 2010, with significant growth in 2011–2012 and 2019–2020. China, the USA, and South Korea are the top three countries in this field, and China has formed good internal cooperative relations. Early studies focused on the clinical efficacy of acupuncture for stroke. In the last five years, more emphasis has been plac...
Source: European Journal of Medical Research - September 21, 2023 Category: Research Source Type: research

The extracellular matrix as modifier of neuroinflammation and recovery in ischemic stroke and intracerebral hemorrhage
Neurobiol Dis. 2023 Sep 6:106282. doi: 10.1016/j.nbd.2023.106282. Online ahead of print.ABSTRACTStroke is the second leading cause of death worldwide and has two major subtypes: ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of ischemic stroke and intracerebral hemorrhage (ICH), contributing to the extent of brain injury but also in its repair. Neuroinflammation is intricately linked to the extracellular matrix (ECM), which is profoundly altered after brain injury and in aging. In the early stages after ischemic stroke and ICH, immune cells are involved in the deposition and remodeling...
Source: Neurobiology of Disease - September 8, 2023 Category: Neurology Authors: Hongmin Li Samira Ghorbani Chang-Chun Ling V Wee Yong Mengzhou Xue Source Type: research

Academy of Plant-based Physical Therapy: overdue to address a nutrition crisis with a transformative population approach
J Phys Ther Sci. 2023 Sep;35(9):645-658. doi: 10.1589/jpts.35.645. Epub 2023 Sep 2.ABSTRACTThis timely evidence synthesis supports the need for an Academy of Plant-based Physical Therapy. Given epidemiological and empirical evidence and the profession's values and practice scope, the time has come for a specialty of plant-based physical therapy based on population health principles. This review connects these factors. Non-communicable diseases (NCDs) are largely nutrition-related resulting from unnatural elements of our diet (i.e., heart disease, several cancers, hypertension, stroke, diabetes, obesity, gastrointestinal di...
Source: Physical Therapy - September 6, 2023 Category: Physiotherapy Authors: Elizabeth Dean Source Type: research

Endovascular repair combined with in situ fenestration for new ‐onset or residual arch dissection in patients underwent aortic replacement
ConclusionOur preliminary experience suggests that endovascular total arch repair combined with ISF technique is a viable, effective and safe option for treatment. Our mid-term results have been promising, but we acknowledge the need for further evaluation to assess long-term outcomes and durability.
Source: Journal of Medical Imaging and Radiation Oncology - September 1, 2023 Category: Radiology Authors: Zhexin Lu, Jin Huang, Yongliang Fan, Hongbing Gu, Xian Zhu, Min Yu, Yizhou Ye Tags: Interventional Radiology —Original Article Source Type: research

A new era of macrophage-based cell therapy
Experimental & Molecular Medicine, Published online: 01 September 2023; doi:10.1038/s12276-023-01068-zTreating disease with the white blood cells called macrophages, in some cases genetically modified, could become an effective clinical option for a range of diseases. Macrophages are cells of the innate (non-specific) immune system that can destroy diseased cells or damaging materials. They can also enhance tissue repair by releasing growth factors and anti-inflammatory molecules. Seung Hyeok Seok and colleagues at Seoul National University in South Korea review the laboratory research and clinical trials that are inve...
Source: Experimental and Molecular Medicine - September 1, 2023 Category: Molecular Biology Authors: Yi Rang Na Sang Wha Kim Seung Hyeok Seok Source Type: research

Parkinson ’ s Patients Get More Mobility And Better Balance With Whole Body Vibration Therapy
I’ve always believed that with a little coaxing, your body can self-heal – and the same is true for your brain. Conventional doctors will never tell you this. For them, being a physician means managing symptoms with Big Pharma meds. But for years, I’ve been helping patients recover using dietary changes, lasers, stem cells, and hyperbaric oxygen (HBOT). These therapies help your body heal itself. No Big Pharma drug can do this. But I recently began researching another natural therapy – called Whole Body Vibration, or WBV – that can help Parkinson’s patients regain their mobility and balance. WBV isn’t new. It...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Natural Cures Source Type: news

Outcomes of aortic valve-sparing root replacement with cusp repair in connective tissue disease
CONCLUSION: Remodelling and aortic valve repair showed excellent durability at 5 years, even in connective tissue disorders.PMID:37640626 | DOI:10.1016/j.acvd.2023.07.005
Source: Archives of Cardiovascular Diseases - August 28, 2023 Category: Cardiology Authors: Pichoy Danial Pierre Demondion Mathieu Debauchez Pascal Leprince Emmanuel Lansac Source Type: research

Exosomes from circRNA-Ptpn4 can modify ADSC treatment and repair nerve damage caused by cerebral infarction by shifting microglial M1/M2 polarization
This study showed that exosomes from hypoxia pretreatment of ADSCs had significant effects in promoting functional recovery following in vivo MCAO, through suppressed inflammatory factor expression, and shifting the microglial from M1 to M2 polarization activation. The results showed that circRNA-Ptpn4 was highly expressed during hypoxia pretreatment of ADSCs exosomes. Exosomes from circ-Ptpn4-modified ADSCs had a greater ability to promote functional recovery. The circ-Ptpn4 delivered from ADSC exosomes induced microglia/macrophage polarization from M1 to M2 by suppressing miR-153-3p and enhancing Nrf2 expressions. Taken ...
Source: Molecular and Cellular Biochemistry - August 26, 2023 Category: Biochemistry Authors: Fei Wang Mei Jiang Yongbin Chi Gang Huang Mingming Jin Source Type: research