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Procedure: Transplants

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Total 3361 results found since Jan 2013.

Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice
CONCLUSIONS: BMSCs increased collateral circulation and improved poststroke outcomes, through the upregulation of Rabep2. These effects were enhanced by hypoxic preconditioning.PMID:37226732 | DOI:10.1161/ATVBAHA.122.318559
Source: Arteriosclerosis, Thrombosis and Vascular Biology - May 25, 2023 Category: Cardiology Authors: Hao Tian Xinxuan Yang Jiahui Zhao Xiran Liu Xin Liu Yuan Cai Alexandra Wehbe Yuchuan Ding Shanping Yu Ling Wei Liping Liu Source Type: research

A brazilian nationwide multicenter study on deficiency of deaminase-2 (DADA2)
CONCLUSION: The low number of patients diagnosed with DADA2 in Brazil reinforces the need for disease awareness for this condition. Moreover, the absence of guidelines for diagnosis and management is also necessary (t).PMID:37217999 | DOI:10.1186/s42358-023-00303-5
Source: Adv Data - May 22, 2023 Category: Epidemiology Authors: Adriana Melo Luciana Martins de Carvalho Virginia Paes Leme Ferriani Andr é Cavalcanti Simone Appenzeller Val éria Rossato Oliveira Herberto Chong Neto Nelson Augusto Ros ário Fabiano de Oliveira Poswar Matheus Xavier Guimaraes Cristina Maria Kokron Ra Source Type: research

Role of cardiovascular magnetic resonance imaging and cardiopulmonary exercise test in predicting composite clinical outcomes in patients with hypertrophic cardiomyopathy
by Ji-won Hwang, Sang-Chol Lee, Darae Kim, Jihoon Kim, Eun Kyoung Kim, Sung-A. Chang, Sung-Ji Park, Sung Mok Kim, Yeon Hyeon Choe, Seung Woo Park We aimed to evaluate the additive value of cardiovascular magnetic resonance imaging (CMR) and cardiopulmonary exercise test (CPET) to predict clinical outcomes in patients with HCM. We enrolled 373 patients with HCM and normal left ventricular systolic function who underwent CPET and CMR. The pri mary outcome was a clinical composite of all-cause death, cardiac transplantation, stroke, heart failure requiring hospitalization and defibrillator implantation. During a follow-up of...
Source: PLoS One - May 16, 2023 Category: Biomedical Science Authors: Ji-won Hwang Source Type: research

When does life end? New organ donation strategy fuels debate
On a chilly holiday Monday in January 2020, a medical milestone passed largely unnoticed. In a New York City operating room, surgeons gently removed the heart from a 43-year-old man who had died and shuttled it steps away to a patient in desperate need of a new one. More than 3500 people in the United States receive a new heart each year. But this case was different—the first of its kind in the country. “It took us 6 months to prepare,” says Nader Moazami, surgical head of heart transplantation at New York University (NYU) Langone Health, where the operation took place. The run-up included oversight from an ethi...
Source: ScienceNOW - May 11, 2023 Category: Science Source Type: news

Correction: Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke
Stem Cell Res Ther. 2023 May 8;14(1):123. doi: 10.1186/s13287-023-03362-z.NO ABSTRACTPMID:37158966 | DOI:10.1186/s13287-023-03362-z
Source: Cell Research - May 9, 2023 Category: Cytology Authors: Satoru Yabuno Takao Yasuhara Takayuki Nagase Satoshi Kawauchi Chiaki Sugahara Yosuke Okazaki Kakeru Hosomoto Susumu Sasada Tatsuya Sasaki Naoki Tajiri Cesar V Borlongan Isao Date Source Type: research

Mitochondrial transplantation and immune response of human bone marrow mesenchymal stem cells for the Therapeutic of ischemic stroke
Curr Stem Cell Res Ther. 2023 May 5. doi: 10.2174/1574888X18666230505103407. Online ahead of print.ABSTRACTIschemic stroke is the leading cause of death and disability worldwide, with increasing incidence and mortality, imposing a significant social and economic burden on patients and their families. However, cerebral vascular occlusion leads to acute loss of neurons and destruction of synaptic structures. The limited treatment options cannot adequately address intra-neuronal mitochondrial dysfunction due to stroke. Therefore, stem cell-derived mitochondria transplantation plays an important role in neuronal protection and...
Source: Current Stem Cell Research and Therapy - May 8, 2023 Category: Stem Cells Authors: Yidong Liao Jiang Ming Wenxue Song Guangtang Chen Junshuan Cui Longcai He Zili Wang Xudong Wang Mingsong Xiong Hua Yang Kaya Xu Source Type: research

Cytomegalovirus and cardiovascular disease: a hypothetical role for viral G protein-coupled receptors in hypertension
Am J Hypertens. 2023 May 6:hpad045. doi: 10.1093/ajh/hpad045. Online ahead of print.ABSTRACTCytomegalovirus (CMV) is a member of the β- herpesviruses and is ubiquitous, infecting 50-99% of the human population depending on ethnic and socioeconomic conditions. CMV establishes lifelong, latent infections in their host. Spontaneous reactivation of CMV is usually asymptomatic, but reactivation events in immunocompromised or immunosuppressed individuals can lead to severe morbidity and mortality. Moreover, herpesvirus infections have been associated with several cardiovascular and post-transplant diseases (stroke, atherosclero...
Source: American Journal of Hypertension - May 6, 2023 Category: Cardiology Authors: Gisele F Bomfim Fernanda Priviero Emma Poole Rita C Tostes John H Sinclair Dimitrios Stamou Mark J Uline Mark R Wills R Clinton Webb Source Type: research